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Intergenerational Influence of Paternal Obesity on Metabolic and Reproductive Health Parameters of the Offspring: Male-Preferential Impact and Involvement of Kiss1-Mediated Pathways.
Sanchez-Garrido MA, Ruiz-Pino F, Velasco I, Barroso A, Fernandois D, Heras V, Manfredi-Lozano M, Vazquez MJ, Castellano JM, Roa J, Pinilla L, Tena-Sempere M. Sanchez-Garrido MA, et al. Among authors: velasco i. Endocrinology. 2018 Feb 1;159(2):1005-1018. doi: 10.1210/en.2017-00705. Endocrinology. 2018. PMID: 29309558 Free article.
Sex-Biased Physiological Roles of NPFF1R, the Canonical Receptor of RFRP-3, in Food Intake and Metabolic Homeostasis Revealed by its Congenital Ablation in mice.
Leon S, Velasco I, Vázquez MJ, Barroso A, Beiroa D, Heras V, Ruiz-Pino F, Manfredi-Lozano M, Romero-Ruiz A, Sanchez-Garrido MA, Dieguez C, Pinilla L, Roa J, Nogueiras R, Tena-Sempere M. Leon S, et al. Among authors: velasco i. Metabolism. 2018 Oct;87:87-97. doi: 10.1016/j.metabol.2018.07.003. Epub 2018 Jul 31. Metabolism. 2018. PMID: 30075164
Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis.
Velasco I, León S, Barroso A, Ruiz-Pino F, Heras V, Torres E, León M, Ruohonen ST, García-Galiano D, Romero-Ruiz A, Sánchez-Garrido MA, Ohlsson C, Castellano JM, Roa J, Poutanen M, Pinilla L, Vázquez MJ, Tena-Sempere M. Velasco I, et al. Metabolism. 2019 Sep;98:84-94. doi: 10.1016/j.metabol.2019.06.007. Epub 2019 Jun 19. Metabolism. 2019. PMID: 31226351
Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity.
Palomares B, Ruiz-Pino F, Garrido-Rodriguez M, Eugenia Prados M, Sánchez-Garrido MA, Velasco I, Vazquez MJ, Nadal X, Ferreiro-Vera C, Morrugares R, Appendino G, Calzado MA, Tena-Sempere M, Muñoz E. Palomares B, et al. Among authors: velasco i. Biochem Pharmacol. 2020 Jan;171:113693. doi: 10.1016/j.bcp.2019.113693. Epub 2019 Nov 9. Biochem Pharmacol. 2020. PMID: 31706843 Free article.
Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty.
Heras V, Castellano JM, Fernandois D, Velasco I, Rodríguez-Vazquez E, Roa J, Vazquez MJ, Ruiz-Pino F, Rubio M, Pineda R, Torres E, Avendaño MS, Paredes A, Pinilla L, Belsham D, Diéguez C, Gaytán F, Casals N, López M, Tena-Sempere M. Heras V, et al. Among authors: velasco i. Cell Metab. 2020 Dec 1;32(6):951-966.e8. doi: 10.1016/j.cmet.2020.10.001. Epub 2020 Oct 19. Cell Metab. 2020. PMID: 33080217 Free article.
Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice.
Roa J, Ruiz-Cruz M, Ruiz-Pino F, Onieva R, Vazquez MJ, Sanchez-Tapia MJ, Ruiz-Rodriguez JM, Sobrino V, Barroso A, Heras V, Velasco I, Perdices-Lopez C, Ohlsson C, Avendaño MS, Prevot V, Poutanen M, Pinilla L, Gaytan F, Tena-Sempere M. Roa J, et al. Among authors: velasco i. Nat Commun. 2022 Aug 9;13(1):4663. doi: 10.1038/s41467-022-32347-4. Nat Commun. 2022. PMID: 35945211 Free PMC article.
Dissecting the KNDy hypothesis: KNDy neuron-derived kisspeptins are dispensable for puberty but essential for preserved female fertility and gonadotropin pulsatility.
Velasco I, Franssen D, Daza-Dueñas S, Skrapits K, Takács S, Torres E, Rodríguez-Vazquez E, Ruiz-Cruz M, León S, Kukoricza K, Zhang FP, Ruohonen S, Luque-Cordoba D, Priego-Capote F, Gaytan F, Ruiz-Pino F, Hrabovszky E, Poutanen M, Vázquez MJ, Tena-Sempere M. Velasco I, et al. Metabolism. 2023 Jul;144:155556. doi: 10.1016/j.metabol.2023.155556. Epub 2023 Apr 29. Metabolism. 2023. PMID: 37121307 Free article.
Congenital ablation of Tacr2 reveals overlapping and redundant roles of NK2R signaling in the control of reproductive axis.
Torres E, Velasco I, Franssen D, Heras V, Gaytan F, Leon S, Navarro VM, Pineda R, Candenas ML, Romero-Ruiz A, Tena-Sempere M. Torres E, et al. Among authors: velasco i. Am J Physiol Endocrinol Metab. 2021 Mar 1;320(3):E496-E511. doi: 10.1152/ajpendo.00346.2020. Epub 2021 Jan 11. Am J Physiol Endocrinol Metab. 2021. PMID: 33427049 Free PMC article.
286 results