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Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.
Matre P, Velez J, Jacamo R, Qi Y, Su X, Cai T, Chan SM, Lodi A, Sweeney SR, Ma H, Davis RE, Baran N, Haferlach T, Su X, Flores ER, Gonzalez D, Konoplev S, Samudio I, DiNardo C, Majeti R, Schimmer AD, Li W, Wang T, Tiziani S, Konopleva M. Matre P, et al. Among authors: velez j. Oncotarget. 2016 Nov 29;7(48):79722-79735. doi: 10.18632/oncotarget.12944. Oncotarget. 2016. PMID: 27806325 Free PMC article.
Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models.
Benito J, Ramirez MS, Millward NZ, Velez J, Harutyunyan KG, Lu H, Shi YX, Matre P, Jacamo R, Ma H, Konoplev S, McQueen T, Volgin A, Protopopova M, Mu H, Lee J, Bhattacharya PK, Marszalek JR, Davis RE, Bankson JA, Cortes JE, Hart CP, Andreeff M, Konopleva M. Benito J, et al. Among authors: velez j. Clin Cancer Res. 2016 Apr 1;22(7):1687-98. doi: 10.1158/1078-0432.CCR-14-3378. Epub 2015 Nov 24. Clin Cancer Res. 2016. PMID: 26603259 Free PMC article.
Platelets promote mitochondrial uncoupling and resistance to apoptosis in leukemia cells: a novel paradigm for the bone marrow microenvironment.
Velez J, Enciso LJ, Suarez M, Fiegl M, Grismaldo A, López C, Barreto A, Cardozo C, Palacios P, Morales L, Duque JE, Carmona JU, Konopleva M, Andreeff M, Samudio I. Velez J, et al. Cancer Microenviron. 2014 Aug;7(1-2):79-90. doi: 10.1007/s12307-014-0149-3. Epub 2014 Aug 12. Cancer Microenviron. 2014. PMID: 25112275 Free PMC article.
Pathophysiology of Hepatorenal Syndrome.
Velez JCQ, Latt N, Rodby RA. Velez JCQ, et al. Adv Kidney Dis Health. 2024 Mar;31(2):87-99. doi: 10.1053/j.akdh.2024.01.002. Adv Kidney Dis Health. 2024. PMID: 38649221 Review.
Discovery of the First-in-Class G9a/GLP PROTAC Degrader.
Velez J, Han Y, Yim H, Yang P, Deng Z, Park KS, Kabir M, Kaniskan HÜ, Xiong Y, Jin J. Velez J, et al. J Med Chem. 2024 Apr 25;67(8):6397-6409. doi: 10.1021/acs.jmedchem.3c02394. Epub 2024 Apr 11. J Med Chem. 2024. PMID: 38602846
516 results