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Neutralization-sensitive R5-tropic simian-human immunodeficiency virus SHIV-2873Nip, which carries env isolated from an infant with a recent HIV clade C infection.
Siddappa NB, Song R, Kramer VG, Chenine AL, Velu V, Ong H, Rasmussen RA, Grisson RD, Wood C, Zhang H, Kankasa C, Amara RR, Else JG, Novembre FJ, Montefiori DC, Ruprecht RM. Siddappa NB, et al. Among authors: velu v. J Virol. 2009 Feb;83(3):1422-32. doi: 10.1128/JVI.02066-08. Epub 2008 Nov 19. J Virol. 2009. PMID: 19019970 Free PMC article.
Enhancing SIV-specific immunity in vivo by PD-1 blockade.
Velu V, Titanji K, Zhu B, Husain S, Pladevega A, Lai L, Vanderford TH, Chennareddi L, Silvestri G, Freeman GJ, Ahmed R, Amara RR. Velu V, et al. Nature. 2009 Mar 12;458(7235):206-10. doi: 10.1038/nature07662. Epub 2008 Dec 10. Nature. 2009. PMID: 19078956 Free PMC article.
Relative transmissibility of an R5 clade C simian-human immunodeficiency virus across different mucosae in macaques parallels the relative risks of sexual HIV-1 transmission in humans via different routes.
Chenine AL, Siddappa NB, Kramer VG, Sciaranghella G, Rasmussen RA, Lee SJ, Santosuosso M, Poznansky MC, Velu V, Amara RR, Souder C, Anderson DC, Villinger F, Else JG, Novembre FJ, Strobert E, O'Neil SP, Secor WE, Ruprecht RM. Chenine AL, et al. Among authors: velu v. J Infect Dis. 2010 Apr 15;201(8):1155-63. doi: 10.1086/651274. J Infect Dis. 2010. PMID: 20214475 Free PMC article.
A live attenuated Listeria monocytogenes vaccine vector expressing SIV Gag is safe and immunogenic in macaques and can be administered repeatedly.
Sciaranghella G, Lakhashe SK, Ayash-Rashkovsky M, Mirshahidi S, Siddappa NB, Novembre FJ, Velu V, Amara RR, Zhou C, Li S, Li Z, Frankel FR, Ruprecht RM. Sciaranghella G, et al. Among authors: velu v. Vaccine. 2011 Jan 10;29(3):476-86. doi: 10.1016/j.vaccine.2010.10.072. Epub 2010 Nov 9. Vaccine. 2011. PMID: 21070847 Free PMC article.
Preexisting vaccinia virus immunity decreases SIV-specific cellular immunity but does not diminish humoral immunity and efficacy of a DNA/MVA vaccine.
Kannanganat S, Nigam P, Velu V, Earl PL, Lai L, Chennareddi L, Lawson B, Wilson RL, Montefiori DC, Kozlowski PA, Moss B, Robinson HL, Amara RR. Kannanganat S, et al. Among authors: velu v. J Immunol. 2010 Dec 15;185(12):7262-73. doi: 10.4049/jimmunol.1000751. Epub 2010 Nov 12. J Immunol. 2010. PMID: 21076059 Free PMC article.
107 results