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Stochastic variation in the concentration of a repressor activates GAL genetic switch: implications in evolution of regulatory network.
Bhat PJ, Venkatesh KV. Bhat PJ, et al. Among authors: venkatesh kv. FEBS Lett. 2005 Jan 31;579(3):597-603. doi: 10.1016/j.febslet.2004.12.038. FEBS Lett. 2005. PMID: 15670814
Quantitative model for Gal4p-mediated expression of the galactose/melibiose regulon in Saccharomyces cerevisiae.
Venkatesh KV, Bhat PJ, Kumar RA, Doshi P. Venkatesh KV, et al. Biotechnol Prog. 1999 Jan-Feb;15(1):51-7. doi: 10.1021/bp9801042. Biotechnol Prog. 1999. PMID: 9933513
Allosteric interactions and bifunctionality make the response of glutamine synthetase cascade system of Escherichia coli robust and ultrasensitive.
Mutalik VK, Shah P, Venkatesh KV. Mutalik VK, et al. Among authors: venkatesh kv. J Biol Chem. 2003 Jul 18;278(29):26327-32. doi: 10.1074/jbc.M300129200. Epub 2003 Apr 3. J Biol Chem. 2003. PMID: 12676964
Dynamic model of Escherichia coli tryptophan operon shows an optimal structural design.
Bhartiya S, Rawool S, Venkatesh KV. Bhartiya S, et al. Among authors: venkatesh kv. Eur J Biochem. 2003 Jun;270(12):2644-51. doi: 10.1046/j.1432-1033.2003.03641.x. Eur J Biochem. 2003. PMID: 12787031
Expression of GAL genes in a mutant strain of Saccharomyces cerevisiae lacking GAL80: quantitative model and experimental verification.
Verma M, Bhat PJ, Venkatesh KV. Verma M, et al. Among authors: venkatesh kv. Biotechnol Appl Biochem. 2004 Feb;39(Pt 1):89-97. doi: 10.1042/BA20030119. Biotechnol Appl Biochem. 2004. PMID: 12927024
Quantitative analysis of GAL genetic switch of Saccharomyces cerevisiae reveals that nucleocytoplasmic shuttling of Gal80p results in a highly sensitive response to galactose.
Verma M, Bhat PJ, Venkatesh KV. Verma M, et al. Among authors: venkatesh kv. J Biol Chem. 2003 Dec 5;278(49):48764-9. doi: 10.1074/jbc.M303526200. Epub 2003 Sep 25. J Biol Chem. 2003. PMID: 14512430
Robust global sensitivity in multiple enzyme cascade system explains how the downstream cascade structure may remain unaffected by cross-talk.
Mutalik VK, Singh AP, Edwards JS, Venkatesh KV. Mutalik VK, et al. Among authors: venkatesh kv. FEBS Lett. 2004 Jan 30;558(1-3):79-84. doi: 10.1016/S0014-5793(04)00021-3. FEBS Lett. 2004. PMID: 14759520
Multiple feedback loops are key to a robust dynamic performance of tryptophan regulation in Escherichia coli.
Venkatesh KV, Bhartiya S, Ruhela A. Venkatesh KV, et al. FEBS Lett. 2004 Apr 9;563(1-3):234-40. doi: 10.1016/S0014-5793(04)00310-2. FEBS Lett. 2004. PMID: 15063755
Autoregulation of regulatory proteins is key for dynamic operation of GAL switch in Saccharomyces cerevisiae.
Ruhela A, Verma M, Edwards JS, Bhat PJ, Bhartiya S, Venkatesh KV. Ruhela A, et al. Among authors: venkatesh kv. FEBS Lett. 2004 Oct 8;576(1-2):119-26. doi: 10.1016/j.febslet.2004.09.001. FEBS Lett. 2004. PMID: 15474022
Equilibrium analysis of allosteric interactions shows zero-order effects.
Mutalik VK, Singh AP, Edwards JS, Venkatesh KV. Mutalik VK, et al. Among authors: venkatesh kv. Cell Biochem Biophys. 2004;41(2):179-92. doi: 10.1385/CBB:41:2:179. Cell Biochem Biophys. 2004. PMID: 15475608
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