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Inhibitors of cyclic AMP phosphodiesterase. 3. Synthesis and biological evaluation of pyrido and imidazolyl analogues of 1,2,3,5-tetrahydro-2-oxoimidazo[2,1-b]quinazoline.
Venuti MC, Stephenson RA, Alvarez R, Bruno JJ, Strosberg AM. Venuti MC, et al. J Med Chem. 1988 Nov;31(11):2136-45. doi: 10.1021/jm00119a014. J Med Chem. 1988. PMID: 2846839
Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K.
Palmer JT, Bryant C, Wang DX, Davis DE, Setti EL, Rydzewski RM, Venkatraman S, Tian ZQ, Burrill LC, Mendonca RV, Springman E, McCarter J, Chung T, Cheung H, Janc JW, McGrath M, Somoza JR, Enriquez P, Yu ZW, Strickley RM, Liu L, Venuti MC, Percival MD, Falgueyret JP, Prasit P, Oballa R, Riendeau D, Young RN, Wesolowski G, Rodan SB, Johnson C, Kimmel DB, Rodan G. Palmer JT, et al. Among authors: venuti mc. J Med Chem. 2005 Dec 1;48(24):7520-34. doi: 10.1021/jm058198r. J Med Chem. 2005. PMID: 16302794
Inhibitors of cyclic AMP phosphodiesterase. 1. Analogues of cilostamide and anagrelide.
Jones GH, Venuti MC, Alvarez R, Bruno JJ, Berks AH, Prince A. Jones GH, et al. Among authors: venuti mc. J Med Chem. 1987 Feb;30(2):295-303. doi: 10.1021/jm00385a011. J Med Chem. 1987. PMID: 3027338
Inhibitors of cyclic AMP phosphodiesterase. 2. Structural variations of N-cyclohexyl-N-methyl-4-[(1,2,3,5-tetrahydro- 2-oxoimidazo[2,1-b]quinazolin-7-yl)-oxy]butyramide (RS-82856).
Venuti MC, Jones GH, Alvarez R, Bruno JJ. Venuti MC, et al. J Med Chem. 1987 Feb;30(2):303-18. doi: 10.1021/jm00385a012. J Med Chem. 1987. PMID: 3027339
Topical nonsteroidal antipsoriatic agents. 1. 1,2,3,4-Tetraoxygenated naphthalene derivatives.
Jones GH, Venuti MC, Young JM, Murthy DV, Loe BE, Simpson RA, Berks AH, Spires DA, Maloney PJ, Kruseman M, et al. Jones GH, et al. J Med Chem. 1986 Aug;29(8):1504-11. doi: 10.1021/jm00158a031. J Med Chem. 1986. PMID: 3016268
Inhibitors of cyclic AMP phosphodiesterase. 4. Synthesis and evaluation of potential prodrugs of lixazinone (N-cyclohexyl-N-methyl-4-[(1,2,3,5-tetrahydro-2- oxoimidazo[2,1-b]quinazolin-7-yl)-oxy]butyramide, RS-82856).
Venuti MC, Alvarez R, Bruno JJ, Strosberg AM, Gu L, Chiang HS, Massey IJ, Chu N, Fried JH. Venuti MC, et al. J Med Chem. 1988 Nov;31(11):2145-52. doi: 10.1021/jm00119a015. J Med Chem. 1988. PMID: 2846840
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