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A 'natural' mutation in Saccharomyces cerevisiae strains derived from S288c affects the complex regulatory gene HAP1 (CYP1).
Gaisne M, Bécam AM, Verdière J, Herbert CJ. Gaisne M, et al. Among authors: verdiere j. Curr Genet. 1999 Oct;36(4):195-200. doi: 10.1007/s002940050490. Curr Genet. 1999. PMID: 10541856
Regulation of the expression of iso 2-cytochrome c gene in S. cerevisiae: cloning of the positive regulatory gene CYP1 and identification of the region of its target sequence on the structural gene CYP3.
Verdière J, Creusot F, Guérineau M. Verdière J, et al. Mol Gen Genet. 1985;199(3):524-33. doi: 10.1007/BF00330769. Mol Gen Genet. 1985. PMID: 2993801
CYP3--15: an up-promoter mutation at the ISO-2 cytochrome c structural gene locus and its interaction with other independent regulatory mutations of cytochrome c synthesis in Saccharomyces cerevisiae.
Verdière J, Petrochilo E. Verdière J, et al. Mol Gen Genet. 1979 Sep;175(2):209-16. doi: 10.1007/BF00425538. Mol Gen Genet. 1979. PMID: 229386 No abstract available.
The transcription of NAM7/UPF1 is enhanced in the absence of Cyp1p/Hap1p concomitant with the appearance of an ISF1-NAM7 cotranscript in Saccharomyces cerevisiae.
Altamura N, de Pinto B, Castaldo R, Verdiére J. Altamura N, et al. Among authors: verdiere j. FEBS Lett. 1997 Jun 2;409(1):96-100. doi: 10.1016/s0014-5793(97)00497-3. FEBS Lett. 1997. PMID: 9199511 Free article.
The transcriptional regulator Hap1p (Cyp1p) is essential for anaerobic or heme-deficient growth of Saccharomyces cerevisiae: Genetic and molecular characterization of an extragenic suppressor that encodes a WD repeat protein.
Chantrel Y, Gaisne M, Lions C, Verdière J. Chantrel Y, et al. Among authors: verdiere j. Genetics. 1998 Feb;148(2):559-69. Genetics. 1998. PMID: 9504906 Free PMC article.
Characterization of a promoter mutation in the CYP3 gene of Saccharomyces cerevisiae which cancels regulation by Cyp1p (Hap1p) without affecting its binding site.
Lodi T, Petrochilo E, Gaisne M, Verdière J. Lodi T, et al. Among authors: verdiere j. Mol Gen Genet. 1996 Nov 27;253(1-2):103-10. doi: 10.1007/s004380050302. Mol Gen Genet. 1996. PMID: 9003293
Functional analysis of the zinc cluster domain of the CYP1 (HAP1) complex regulator in heme-sufficient and heme-deficient yeast cells.
Defranoux N, Gaisne M, Verdière J. Defranoux N, et al. Among authors: verdiere j. Mol Gen Genet. 1994 Mar;242(6):699-707. doi: 10.1007/BF00283425. Mol Gen Genet. 1994. PMID: 8152420
CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast. II. Missense mutation suggests alternative Zn fingers as discriminating agents of gene control.
Verdière J, Gaisne M, Guiard B, Defranoux N, Slonimski PP. Verdière J, et al. J Mol Biol. 1988 Nov 20;204(2):277-82. doi: 10.1016/0022-2836(88)90575-x. J Mol Biol. 1988. PMID: 2851659
CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast. I. Overall organization of the protein sequence displays several novel structural domains.
Creusot F, Verdière J, Gaisne M, Slonimski PP. Creusot F, et al. Among authors: verdiere j. J Mol Biol. 1988 Nov 20;204(2):263-76. doi: 10.1016/0022-2836(88)90574-8. J Mol Biol. 1988. PMID: 2851658
The overproducing CYP1 and the underproducing hap1 mutations are alleles of the same gene which regulates in trans the expression of the structural genes encoding iso-cytochromes c.
Verdière J, Creusot F, Guarente L, Slonimski PP. Verdière J, et al. Curr Genet. 1986;10(5):339-42. doi: 10.1007/BF00418404. Curr Genet. 1986. PMID: 2832070
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