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A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment.
Cauwels A, Van Lint S, Garcin G, Bultinck J, Paul F, Gerlo S, Van der Heyden J, Bordat Y, Catteeuw D, De Cauwer L, Rogge E, Verhee A, Uzé G, Tavernier J. Cauwels A, et al. Among authors: Verhee A. Oncoimmunology. 2017 Nov 27;7(3):e1398876. doi: 10.1080/2162402X.2017.1398876. eCollection 2018. Oncoimmunology. 2017. PMID: 29399401 Free PMC article.
Delivering Type I Interferon to Dendritic Cells Empowers Tumor Eradication and Immune Combination Treatments.
Cauwels A, Van Lint S, Paul F, Garcin G, De Koker S, Van Parys A, Wueest T, Gerlo S, Van der Heyden J, Bordat Y, Catteeuw D, Rogge E, Verhee A, Vandekerckhove B, Kley N, Uzé G, Tavernier J. Cauwels A, et al. Among authors: Verhee A. Cancer Res. 2018 Jan 15;78(2):463-474. doi: 10.1158/0008-5472.CAN-17-1980. Epub 2017 Nov 29. Cancer Res. 2018. PMID: 29187401 Free article.
Safe eradication of large established tumors using neovasculature-targeted tumor necrosis factor-based therapies.
Huyghe L, Van Parys A, Cauwels A, Van Lint S, De Munter S, Bultinck J, Zabeau L, Hostens J, Goethals A, Vanderroost N, Verhee A, Uzé G, Kley N, Peelman F, Vandekerckhove B, Brouckaert P, Tavernier J. Huyghe L, et al. Among authors: Verhee A. EMBO Mol Med. 2020 Feb 7;12(2):e11223. doi: 10.15252/emmm.201911223. Epub 2020 Jan 8. EMBO Mol Med. 2020. PMID: 31912630 Free article.
Effect of mutations of N- and C-terminal charged residues on the activity of LCAT.
Peelman F, Vanloo B, Verschelde JL, Labeur C, Caster H, Taveirne J, Verhee A, Duverger N, Vandekerckhove J, Tavernier J, Rosseneu M. Peelman F, et al. Among authors: Verhee A. J Lipid Res. 2001 Apr;42(4):471-9. J Lipid Res. 2001. PMID: 11290818
Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level.
Zabeau L, Jensen CJ, Seeuws S, Venken K, Verhee A, Catteeuw D, van Loo G, Chen H, Walder K, Hollis J, Foote S, Morris MJ, Van der Heyden J, Peelman F, Oldfield BJ, Rubio JP, Elewaut D, Tavernier J. Zabeau L, et al. Among authors: Verhee A. Cell Mol Life Sci. 2015 Feb;72(3):629-644. doi: 10.1007/s00018-014-1697-x. Epub 2014 Aug 7. Cell Mol Life Sci. 2015. PMID: 25098352 Free PMC article.
HyperISGylation of Old World monkey ISG15 in human cells.
Pattyn E, Verhee A, Uyttendaele I, Piessevaux J, Timmerman E, Gevaert K, Vandekerckhove J, Peelman F, Tavernier J. Pattyn E, et al. Among authors: Verhee A. PLoS One. 2008 Jun 18;3(6):e2427. doi: 10.1371/journal.pone.0002427. PLoS One. 2008. PMID: 18560560 Free PMC article.
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