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The role of vitamin K in soft-tissue calcification.
Theuwissen E, Smit E, Vermeer C. Theuwissen E, et al. Among authors: vermeer c. Adv Nutr. 2012 Mar 1;3(2):166-73. doi: 10.3945/an.111.001628. Adv Nutr. 2012. PMID: 22516724 Free PMC article. Review.
Inactive Matrix Gla Protein, Arterial Stiffness, and Endothelial Function in African American Hemodialysis Patients.
Fain ME, Kapuku GK, Paulson WD, Williams CF, Raed A, Dong Y, Knapen MHJ, Vermeer C, Pollock NK. Fain ME, et al. Among authors: vermeer c. Am J Hypertens. 2018 May 7;31(6):735-741. doi: 10.1093/ajh/hpy049. Am J Hypertens. 2018. PMID: 29635270
Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
Knapen MH, Braam LA, Drummen NE, Bekers O, Hoeks AP, Vermeer C. Knapen MH, et al. Among authors: vermeer c. Thromb Haemost. 2015 May;113(5):1135-44. doi: 10.1160/TH14-08-0675. Epub 2015 Feb 19. Thromb Haemost. 2015. PMID: 25694037 Clinical Trial.
Circulating desphospho-uncarboxylated matrix Gla-protein (dp-ucMGP) as well as acute phase markers Interleukin-6 (IL-6), high-sensitive C-reactive protein (hsCRP), tumour necrosis factor-alpha(TNF-alpha) and markers for endothelial dysfunction Vascular Cell Adhesion Molecu …
Circulating desphospho-uncarboxylated matrix Gla-protein (dp-ucMGP) as well as acute phase markers Interleukin-6 (IL-6), high-sensitive C
The realm of vitamin K dependent proteins: shifting from coagulation toward calcification.
Willems BA, Vermeer C, Reutelingsperger CP, Schurgers LJ. Willems BA, et al. Among authors: vermeer c. Mol Nutr Food Res. 2014 Aug;58(8):1620-35. doi: 10.1002/mnfr.201300743. Epub 2014 Feb 17. Mol Nutr Food Res. 2014. PMID: 24668744 Review.
Impaired vitamin K recycling in uremia is rescued by vitamin K supplementation.
Kaesler N, Magdeleyns E, Herfs M, Schettgen T, Brandenburg V, Fliser D, Vermeer C, Floege J, Schlieper G, Krüger T. Kaesler N, et al. Among authors: vermeer c. Kidney Int. 2014 Aug;86(2):286-93. doi: 10.1038/ki.2013.530. Epub 2014 Jan 15. Kidney Int. 2014. PMID: 24429407
Vitamin K2 in different bovine muscles and breeds.
Rødbotten R, Gundersen T, Vermeer C, Kirkhus B. Rødbotten R, et al. Among authors: vermeer c. Meat Sci. 2014 May;97(1):49-53. doi: 10.1016/j.meatsci.2014.01.005. Epub 2014 Jan 22. Meat Sci. 2014. PMID: 24508562
Synthesis of 2-methyl-1,4-naphthoquinones with higher gamma-glutamyl carboxylase activity than MK-4 both in vitro and in vivo.
Vermeer C, van 't Hoofd C, Knapen MHJ, Xanthoulea S. Vermeer C, et al. Bioorg Med Chem Lett. 2017 Jan 15;27(2):208-211. doi: 10.1016/j.bmcl.2016.11.073. Epub 2016 Nov 25. Bioorg Med Chem Lett. 2017. PMID: 27955810
Derivatives with C-14 and C-16 tails showed the highest in vitro bioactivity resulting in 2.5 and 2-fold higher carboxylated osteocalcin synthesis in MG63 cells than menaquinone-4 (MK-4, form of vitamin K2). ...The C-14 tail derivative was able to counteract …
Derivatives with C-14 and C-16 tails showed the highest in vitro bioactivity resulting in 2.5 and 2-fold higher carboxylated o …
Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling.
Willems BA, Furmanik M, Caron MMJ, Chatrou MLL, Kusters DHM, Welting TJM, Stock M, Rafael MS, Viegas CSB, Simes DC, Vermeer C, Reutelingsperger CPM, Schurgers LJ. Willems BA, et al. Among authors: vermeer c. Sci Rep. 2018 Mar 21;8(1):4961. doi: 10.1038/s41598-018-23353-y. Sci Rep. 2018. PMID: 29563538 Free PMC article.
Gla-rich protein is involved in the cross-talk between calcification and inflammation in osteoarthritis.
Cavaco S, Viegas CS, Rafael MS, Ramos A, Magalhães J, Blanco FJ, Vermeer C, Simes DC. Cavaco S, et al. Among authors: vermeer c. Cell Mol Life Sci. 2016 Mar;73(5):1051-65. doi: 10.1007/s00018-015-2033-9. Epub 2015 Sep 4. Cell Mol Life Sci. 2016. PMID: 26337479
Gla-rich protein is a potential new vitamin K target in cancer: evidences for a direct GRP-mineral interaction.
Viegas CS, Herfs M, Rafael MS, Enriquez JL, Teixeira A, Luís IM, van 't Hoofd CM, João A, Maria VL, Cavaco S, Ferreira A, Serra M, Theuwissen E, Vermeer C, Simes DC. Viegas CS, et al. Among authors: vermeer c. Biomed Res Int. 2014;2014:340216. doi: 10.1155/2014/340216. Epub 2014 May 18. Biomed Res Int. 2014. PMID: 24949434 Free PMC article.
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