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Attenuated luteinizing hormone (LH) pulse amplitude but normal LH pulse frequency, and its relation to plasma androgens in hypogonadism of obese men.
Vermeulen A, Kaufman JM, Deslypere JP, Thomas G. Vermeulen A, et al. J Clin Endocrinol Metab. 1993 May;76(5):1140-6. doi: 10.1210/jcem.76.5.8496304. J Clin Endocrinol Metab. 1993. PMID: 8496304
To evaluate the effects of obesity on the hypothalamo-pituitary-testicular axis, we compared total and free (FT) testosterone (T), androstenedione, dehydroepiandrosterone and its sulfate, and 5 alpha-androstane-3 alpha, 17 beta-diol glucuronide, and estradiol levels in a g …
To evaluate the effects of obesity on the hypothalamo-pituitary-testicular axis, we compared total and free (FT) testosterone (T), androsten …
The decline of androgen levels in elderly men and its clinical and therapeutic implications.
Kaufman JM, Vermeulen A. Kaufman JM, et al. Among authors: vermeulen a. Endocr Rev. 2005 Oct;26(6):833-76. doi: 10.1210/er.2004-0013. Epub 2005 May 18. Endocr Rev. 2005. PMID: 15901667 Review.
Aging in men is accompanied by a progressive, but individually variable decline of serum testosterone production, more than 20% of healthy men over 60 yr of age presenting with serum levels below the range for young men. ...To date, only a few hundred elderly men ha …
Aging in men is accompanied by a progressive, but individually variable decline of serum testosterone production, more than 20% of he …
Androgen supplementation in elderly males: is dihydrotestosterone to be preferred?
Vermeulen A. Vermeulen A. Aging Male. 2004 Dec;7(4):325-7. doi: 10.1080/13685530400016672. Aging Male. 2004. PMID: 15799129 No abstract available.
[Senile hypogonadism in man and hormone replacement therapy].
Vermeulen A. Vermeulen A. Acta Med Austriaca. 2000;27(1):11-7. doi: 10.1046/j.1563-2571.2000.200103.x. Acta Med Austriaca. 2000. PMID: 10812457 Review. German.
Aging is accompanied by a progressive decline of testicular function. Whereas fertility persists until a very old age, endocrine function declines progressively and at age 70 yrs, more than 25% of men have hypogonadal testosterone levels. This decline in testosteron …
Aging is accompanied by a progressive decline of testicular function. Whereas fertility persists until a very old age, endocri …
Androgen replacement therapy in the aging male--a critical evaluation.
Vermeulen A. Vermeulen A. J Clin Endocrinol Metab. 2001 Jun;86(6):2380-90. doi: 10.1210/jcem.86.6.7630. J Clin Endocrinol Metab. 2001. PMID: 11397827 Review. No abstract available.
Reflections concerning biochemical parameters of androgenicity.
Vermeulen A. Vermeulen A. Aging Male. 2004 Dec;7(4):280-9. doi: 10.1080/13685530400016615. Aging Male. 2004. PMID: 15799123 Review.
Due to the highly variable concentration of sex hormone binding globulin (SHBG) and the many factors affecting it, the evaluation of the androgen status may require the measurement of a parameter of bioactive plasma testosterone. ...The limitations of the free testosterone …
Due to the highly variable concentration of sex hormone binding globulin (SHBG) and the many factors affecting it, the evaluation of the and …
[Metabolic effects of obesity in men].
Vermeulen A. Vermeulen A. Verh K Acad Geneeskd Belg. 1993;55(5):383-93; discussion 393-7. Verh K Acad Geneeskd Belg. 1993. PMID: 8128779 Dutch.
In men with a body mass index (BMI = W (kg)/L2 (m)) of more than 35, the glucose metabolism was disturbed in 70%, the lipid spectrum had a clearly atherogenic profile, the average (free) testosterone level was significantly diminished and there was also a cer …
In men with a body mass index (BMI = W (kg)/L2 (m)) of more than 35, the glucose metabolism was disturbed in 70%, the lipid spectrum …
Decreased androgen levels and obesity in men.
Vermeulen A. Vermeulen A. Ann Med. 1996 Feb;28(1):13-5. doi: 10.3109/07853899608999068. Ann Med. 1996. PMID: 8932500 Review.
Obesity in males is accompanied by a significant decrease in testosterone levels. This decrease is essentially a consequence of the decrease of the sex hormone binding hormone (SHBG) binding capacity, itself probably the consequence of the increased insulin levels. …
Obesity in males is accompanied by a significant decrease in testosterone levels. This decrease is essentially a consequence o …
Andropause.
Vermeulen A. Vermeulen A. Maturitas. 2000 Jan 15;34(1):5-15. doi: 10.1016/s0378-5122(99)00075-4. Maturitas. 2000. PMID: 10687877 Review.
Aging is accompanied by a series of signs and symptoms, many of which are rather similar to those observed in young hypogonadal males. ...So far, there are no indications that testosterone would stimulate the evolution of as subclinical prostatic carcinoma to a clin …
Aging is accompanied by a series of signs and symptoms, many of which are rather similar to those observed in young hypogonadal males …
Hormonal effects of an orally active 4-azasteroid inhibitor of 5 alpha-reductase in humans.
Vermeulen A, Giagulli VA, De Schepper P, Buntinx A, Stoner E. Vermeulen A, et al. Prostate. 1989;14(1):45-53. doi: 10.1002/pros.2990140106. Prostate. 1989. PMID: 2538808
Twenty-four hours after a single 5- to 40-mg dose (n = 24), plasma DHT levels decreased by a mean of +/- 65%, with slow recovery of DHT levels. ...A single dose of 0.2 mg appeared to be slightly active as a 5 alpha-reductase inhibitor, but no statistic …
Twenty-four hours after a single 5- to 40-mg dose (n = 24), plasma DHT levels decreased by a mean of +/- 65%, with slow recove …
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