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Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma.
Pandey GK, Landman N, Neikes HK, Hulsman D, Lieftink C, Beijersbergen R, Kolluri KK, Janes SM, Vermeulen M, Badhai J, van Lohuizen M. Pandey GK, et al. Among authors: vermeulen m. Cell Rep Med. 2023 Feb 21;4(2):100915. doi: 10.1016/j.xcrm.2022.100915. Epub 2023 Jan 18. Cell Rep Med. 2023. PMID: 36657447 Free PMC article.
Inhibition of CSF-1R and IL-6R prevents conversion of cDC2s into immune incompetent tumor-induced DC3s boosting DC-driven therapy potential.
Becker AMD, Decker AH, Flórez-Grau G, Bakdash G, Röring RJ, Stelloo S, Vermeulen M, Piet B, Aarntzen EHJG, Verdoes M, de Vries IJM. Becker AMD, et al. Among authors: vermeulen m. Cell Rep Med. 2024 Feb 20;5(2):101386. doi: 10.1016/j.xcrm.2023.101386. Epub 2024 Jan 18. Cell Rep Med. 2024. PMID: 38242119 Free PMC article.
Acid ceramidase regulates innate immune memory.
Rother N, Yanginlar C, Prévot G, Jonkman I, Jacobs M, van Leent MMT, van Heck J, Matzaraki V, Azzun A, Morla-Folch J, Ranzenigo A, Wang W, van der Meel R, Fayad ZA, Riksen NP, Hilbrands LB, Lindeboom RGH, Martens JHA, Vermeulen M, Joosten LAB, Netea MG, Mulder WJM, van der Vlag J, Teunissen AJP, Duivenvoorden R. Rother N, et al. Among authors: vermeulen m. Cell Rep. 2023 Dec 26;42(12):113458. doi: 10.1016/j.celrep.2023.113458. Epub 2023 Nov 22. Cell Rep. 2023. PMID: 37995184 Free article.
Profiling of plasma extracellular vesicles identifies proteins that strongly associate with patient's global assessment of disease activity in rheumatoid arthritis.
Arntz OJ, Thurlings RM, Blaney Davidson EN, Jansen PWTC, Vermeulen M, Koenders MI, van der Kraan PM, van de Loo FAJ. Arntz OJ, et al. Among authors: vermeulen m. Front Med (Lausanne). 2024 Jan 11;10:1247778. doi: 10.3389/fmed.2023.1247778. eCollection 2023. Front Med (Lausanne). 2024. PMID: 38274452 Free PMC article.
Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer.
Brouwer NP, Webbink L, Haddad TS, Rutgers N, van Vliet S, Wood CS, Jansen PW, Lafarge MW; imCMS Consortium; de Wilt JH, Hugen N, Simmer F, Jamieson NB, Tauriello DV, Kölzer VH, Vermeulen M, Nagtegaal ID. Brouwer NP, et al. Among authors: vermeulen m. J Pathol. 2023 Dec;261(4):401-412. doi: 10.1002/path.6196. Epub 2023 Oct 4. J Pathol. 2023. PMID: 37792663
A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance.
van der Krift F, Zijlmans DW, Shukla R, Javed A, Koukos PI, Schwarz LL, Timmermans-Sprang EP, Maas PE, Gahtory D, van den Nieuwboer M, Mol JA, Strous GJ, Bonvin AM, van der Stelt M, Veldhuizen EJ, Weingarth M, Vermeulen M, Klumperman J, Maurice MM. van der Krift F, et al. Among authors: vermeulen m. Life Sci Alliance. 2023 Aug 17;6(11):e202302058. doi: 10.26508/lsa.202302058. Print 2023 Nov. Life Sci Alliance. 2023. PMID: 37591722 Free PMC article.
Myeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways.
van Wigcheren GF, Cuenca-Escalona J, Stelloo S, Brake J, Peeters E, Horrevorts SK, Frölich S, Ramos-Tomillero I, Wesseling-Rozendaal Y, van Herpen CML, van de Stolpe A, Vermeulen M, de Vries IJM, Figdor CG, Flórez-Grau G. van Wigcheren GF, et al. Among authors: vermeulen m. J Biol Chem. 2023 Nov;299(11):105276. doi: 10.1016/j.jbc.2023.105276. Epub 2023 Sep 20. J Biol Chem. 2023. PMID: 37739035 Free PMC article.
1,030 results