Vermeulen NP - Search Results

1

The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae.

Huseinovic A, van Leeuwen JS, van Welsem T, Stulemeijer I, van Leeuwen F, Vermeulen NP, Kooter JM, Vos JC. Huseinovic A, et al. Among authors: vermeulen np. PLoS One. 2017 Mar 14;12(3):e0173573. doi: 10.1371/journal.pone.0173573. eCollection 2017. PLoS One. 2017. PMID: 28291796 Free PMC article.

2

Involvement of the pleiotropic drug resistance response, protein kinase C signaling, and altered zinc homeostasis in resistance of Saccharomyces cerevisiae to diclofenac.

van Leeuwen JS, Vermeulen NP, Vos JC. van Leeuwen JS, et al. Among authors: vermeulen np. Appl Environ Microbiol. 2011 Sep;77(17):5973-80. doi: 10.1128/AEM.00253-11. Epub 2011 Jul 1. Appl Environ Microbiol. 2011. PMID: 21724882 Free PMC article.

3

Drug toxicity profiling of a Saccharomyces cerevisiae deubiquitinase deletion panel shows that acetaminophen mimics tyrosine.

Huseinovic A, van Dijk M, Vermeulen NPE, van Leeuwen F, Kooter JM, Vos JC. Huseinovic A, et al. Toxicol In Vitro. 2018 Mar;47:259-268. doi: 10.1016/j.tiv.2017.12.007. Epub 2017 Dec 16. Toxicol In Vitro. 2018. PMID: 29258884 Free article.

4

Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion.

Huseinovic A, Dekker SJ, Boogaard B, Vermeulen NPE, Kooter JM, Vos JC. Huseinovic A, et al. Amino Acids. 2018 Oct;50(10):1377-1390. doi: 10.1007/s00726-018-2613-8. Epub 2018 Jul 5. Amino Acids. 2018. PMID: 29978260 Free PMC article.

5

Metabolism related toxicity of diclofenac in yeast as model system.

van Leeuwen JS, Vredenburg G, Dragovic S, Tjong TF, Vos JC, Vermeulen NP. van Leeuwen JS, et al. Among authors: vermeulen np. Toxicol Lett. 2011 Feb 5;200(3):162-8. doi: 10.1016/j.toxlet.2010.11.010. Epub 2010 Nov 24. Toxicol Lett. 2011. PMID: 21111035

6

Subunits Rip1p and Cox9p of the respiratory chain contribute to diclofenac-induced mitochondrial dysfunction.

van Leeuwen JS, Orij R, Luttik MAH, Smits GJ, Vermeulen NPE, Vos JC. van Leeuwen JS, et al. Microbiology (Reading). 2011 Mar;157(Pt 3):685-694. doi: 10.1099/mic.0.044578-0. Epub 2010 Dec 9. Microbiology (Reading). 2011. PMID: 21148204 Free article.

7

Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.

van Leeuwen JS, Unlü B, Vermeulen NP, Vos JC. van Leeuwen JS, et al. Among authors: vermeulen np. Toxicol In Vitro. 2012 Mar;26(2):197-205. doi: 10.1016/j.tiv.2011.11.013. Epub 2011 Nov 26. Toxicol In Vitro. 2012. PMID: 22138569

8

Yeast as a humanized model organism for biotransformation-related toxicity.

van Leeuwen JS, Vermeulen NP, Chris Vos J. van Leeuwen JS, et al. Among authors: vermeulen np. Curr Drug Metab. 2012 Dec;13(10):1464-75. doi: 10.2174/138920012803762783. Curr Drug Metab. 2012. PMID: 22935071 Review.

9

Reconstitution of the interplay between cytochrome P450 and human glutathione S-transferases in clozapine metabolism in yeast.

Vredenburg G, Vassell KP, Commandeur JN, Vermeulen NP, Vos JC. Vredenburg G, et al. Among authors: vermeulen np. Toxicol Lett. 2013 Oct 9;222(3):247-56. doi: 10.1016/j.toxlet.2013.07.023. Epub 2013 Aug 2. Toxicol Lett. 2013. PMID: 23916688

10

Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer.

den Braver-Sewradj SP, den Braver MW, Vermeulen NP, Commandeur JN, Richert L, Vos JC. den Braver-Sewradj SP, et al. Among authors: vermeulen np. Toxicol In Vitro. 2016 Jun;33:71-9. doi: 10.1016/j.tiv.2016.02.013. Epub 2016 Feb 26. Toxicol In Vitro. 2016. PMID: 26921663

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