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The role of AP-1 and epigenetics in ALCL.
Schiefer AI, Vesely P, Hassler MR, Egger G, Kenner L. Schiefer AI, et al. Among authors: vesely p. Front Biosci (Schol Ed). 2015 Jun 1;7:226-35. Front Biosci (Schol Ed). 2015. PMID: 25961698 Review.
The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling.
Staber PB, Vesely P, Haq N, Ott RG, Funato K, Bambach I, Fuchs C, Schauer S, Linkesch W, Hrzenjak A, Dirks WG, Sexl V, Bergler H, Kadin ME, Sternberg DW, Kenner L, Hoefler G. Staber PB, et al. Among authors: vesely p. Blood. 2007 Nov 1;110(9):3374-83. doi: 10.1182/blood-2007-02-071258. Epub 2007 Aug 9. Blood. 2007. PMID: 17690253
Translational regulation mechanisms of AP-1 proteins.
Vesely PW, Staber PB, Hoefler G, Kenner L. Vesely PW, et al. Mutat Res. 2009 Jul-Aug;682(1):7-12. doi: 10.1016/j.mrrev.2009.01.001. Epub 2009 Jan 9. Mutat Res. 2009. PMID: 19167516 Review.
PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Laimer D, Dolznig H, Kollmann K, Vesely PW, Schlederer M, Merkel O, Schiefer AI, Hassler MR, Heider S, Amenitsch L, Thallinger C, Staber PB, Simonitsch-Klupp I, Artaker M, Lagger S, Turner SD, Pileri S, Piccaluga PP, Valent P, Messana K, Landra I, Weichhart T, Knapp S, Shehata M, Todaro M, Sexl V, Höfler G, Piva R, Medico E, Ruggeri BA, Cheng M, Eferl R, Egger G, Penninger JM, Jaeger U, Moriggl R, Inghirami G, Kenner L. Laimer D, et al. Among authors: vesely pw. Nat Med. 2012 Nov;18(11):1699-704. doi: 10.1038/nm.2966. Epub 2012 Oct 14. Nat Med. 2012. PMID: 23064464
The PPARα agonist fenofibrate suppresses B-cell lymphoma in mice by modulating lipid metabolism.
Huang J, Das SK, Jha P, Al Zoughbi W, Schauer S, Claudel T, Sexl V, Vesely P, Birner-Gruenberger R, Kratky D, Trauner M, Hoefler G. Huang J, et al. Among authors: vesely p. Biochim Biophys Acta. 2013 Oct;1831(10):1555-65. doi: 10.1016/j.bbalip.2013.04.012. Epub 2013 Apr 26. Biochim Biophys Acta. 2013. PMID: 23628473 Free PMC article.
Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling.
Pflegerl P, Vesely P, Hantusch B, Schlederer M, Zenz R, Janig E, Steiner G, Meixner A, Petzelbauer P, Wolf P, Soleiman A, Egger G, Moriggl R, Kishimoto T, Wagner EF, Kenner L. Pflegerl P, et al. Among authors: vesely p. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20423-8. doi: 10.1073/pnas.0910371106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918056 Free PMC article.
Adipose triglyceride lipase contributes to cancer-associated cachexia.
Das SK, Eder S, Schauer S, Diwoky C, Temmel H, Guertl B, Gorkiewicz G, Tamilarasan KP, Kumari P, Trauner M, Zimmermann R, Vesely P, Haemmerle G, Zechner R, Hoefler G. Das SK, et al. Among authors: vesely p. Science. 2011 Jul 8;333(6039):233-8. doi: 10.1126/science.1198973. Epub 2011 Jun 16. Science. 2011. PMID: 21680814
miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms.
Senanayake U, Das S, Vesely P, Alzoughbi W, Fröhlich LF, Chowdhury P, Leuschner I, Hoefler G, Guertl B. Senanayake U, et al. Among authors: vesely p. Carcinogenesis. 2012 May;33(5):1014-21. doi: 10.1093/carcin/bgs126. Epub 2012 Mar 19. Carcinogenesis. 2012. PMID: 22431721
Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58.
Das SK, Stadelmeyer E, Schauer S, Schwarz A, Strohmaier H, Claudel T, Zechner R, Hoefler G, Vesely PW. Das SK, et al. Int J Mol Sci. 2015 Apr 16;16(4):8555-68. doi: 10.3390/ijms16048555. Int J Mol Sci. 2015. PMID: 25894224 Free PMC article.
Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Al-Zoughbi W, Pichler M, Gorkiewicz G, Guertl-Lackner B, Haybaeck J, Jahn SW, Lackner C, Liegl-Atzwanger B, Popper H, Schauer S, Nusshold E, Kindt AS, Trajanoski Z, Speicher MR, Haemmerle G, Zimmermann R, Zechner R, Vesely PW, Hoefler G. Al-Zoughbi W, et al. Oncotarget. 2016 Jun 7;7(23):33832-40. doi: 10.18632/oncotarget.9418. Oncotarget. 2016. PMID: 27213586 Free PMC article.
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