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1972 3
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1974 3
1975 10
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1995 96
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2002 114
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4,161 results

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Page 1
Did you mean desiccant exposure (1,560 results)?
Vesicants.
McManus J, Huebner K. McManus J, et al. Crit Care Clin. 2005 Oct;21(4):707-18, vi. doi: 10.1016/j.ccc.2005.06.005. Crit Care Clin. 2005. PMID: 16168310 Review.
Vesicants (or blister agents) are cytotoxic alkylating compounds, which are chemical agents sometimes collectively known as mustard gas or simply as mustard. Other blister agents are nitrogen mustard; sulfur mustard; lewisite, a vesicant that contains …
Vesicants (or blister agents) are cytotoxic alkylating compounds, which are chemical agents sometimes collectively known as mu …
Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure.
Shakarjian MP, Heck DE, Gray JP, Sinko PJ, Gordon MK, Casillas RP, Heindel ND, Gerecke DR, Laskin DL, Laskin JD. Shakarjian MP, et al. Toxicol Sci. 2010 Mar;114(1):5-19. doi: 10.1093/toxsci/kfp253. Epub 2009 Oct 15. Toxicol Sci. 2010. PMID: 19833738 Free PMC article. Review.
Several in vivo and in vitro models have been established to understand the pathology and investigate the mechanism of action of this vesicating agent in the skin. SM is a bifunctional alkylating agent which reacts with many targets including lipids, proteins, and DNA, for …
Several in vivo and in vitro models have been established to understand the pathology and investigate the mechanism of action of this ves …
Occupational asthma.
Tarlo SM, Lemiere C. Tarlo SM, et al. N Engl J Med. 2014 Feb 13;370(7):640-9. doi: 10.1056/NEJMra1301758. N Engl J Med. 2014. PMID: 24521110 Review.
Occupational asthma has been defined as asthma due to conditions attributable to work exposures, not to causes outside the workplace. This review focuses on current data on pathogenesis, evaluation, and management....
Occupational asthma has been defined as asthma due to conditions attributable to work exposures, not to causes outside the workplace. …
Occupational asthma.
Cormier M, Lemière C. Cormier M, et al. Int J Tuberc Lung Dis. 2020 Jan 1;24(1):8-21. doi: 10.5588/ijtld.19.0301. Int J Tuberc Lung Dis. 2020. PMID: 32005302
Early and accurate diagnosis of OA through comprehensive testing is primordial to avoid unwarranted removal from exposure and to allow early management of confirmed cases. Despite optimal management, up to 70% of patients with OA will have persistent asthma several years a …
Early and accurate diagnosis of OA through comprehensive testing is primordial to avoid unwarranted removal from exposure and to allo …
Irritant-induced asthma.
Labrecque M. Labrecque M. Curr Opin Allergy Clin Immunol. 2012 Apr;12(2):140-4. doi: 10.1097/ACI.0b013e32835143b8. Curr Opin Allergy Clin Immunol. 2012. PMID: 22327170 Review.
RECENT FINDINGS: IIA is a subtype of occupational asthma without immunologic sensitization and includes the typical reactive airway dysfunction syndrome (RADS) and a more gradual form called not-so-sudden IIA, when onset of asthma follows repeated low-dose exposure to i …
RECENT FINDINGS: IIA is a subtype of occupational asthma without immunologic sensitization and includes the typical reactive airway dysfunct …
Cutaneous exposure to vesicant phosgene oxime: Acute effects on the skin and systemic toxicity.
Tewari-Singh N, Goswami DG, Kant R, Croutch CR, Casillas RP, Orlicky DJ, Agarwal R. Tewari-Singh N, et al. Toxicol Appl Pharmacol. 2017 Feb 15;317:25-32. doi: 10.1016/j.taap.2017.01.003. Epub 2017 Jan 11. Toxicol Appl Pharmacol. 2017. PMID: 28087322
Phosgene Oxime (CX), an urticant or nettle agent categorized as a vesicant, is a potential chemical warfare and terrorist weapon. Its exposure can result in widespread and devastating effects including high mortality due to its fast penetration and ability to cause …
Phosgene Oxime (CX), an urticant or nettle agent categorized as a vesicant, is a potential chemical warfare and terrorist weapon. Its …
Toxin-induced respiratory distress.
McKay CA Jr. McKay CA Jr. Emerg Med Clin North Am. 2014 Feb;32(1):127-47. doi: 10.1016/j.emc.2013.09.003. Emerg Med Clin North Am. 2014. PMID: 24275172 Review.
Simple asphyxiants displace oxygen from the inspired air. Respiratory irritants include water-soluble and water-insoluble compounds. Several inhaled agents produce direct airway injury, which may be mediated by caustic, thermal, and hydrocarbon exposures. ...The pul …
Simple asphyxiants displace oxygen from the inspired air. Respiratory irritants include water-soluble and water-insoluble compounds. …
Countermeasures against Pulmonary Threat Agents.
Marzec J, Nadadur S. Marzec J, et al. J Pharmacol Exp Ther. 2024 Jan 17;388(2):560-567. doi: 10.1124/jpet.123.001822. J Pharmacol Exp Ther. 2024. PMID: 37863486 Free PMC article. Review.
Despite laws and regulatory agencies that regulate use, storage, transport, emissions, and disposal, inhalational exposures continue to cause lasting lung injury. Industrial irritants (e.g., ammonia) aggravate the upper respiratory tract, causing pneumonitis, bronch …
Despite laws and regulatory agencies that regulate use, storage, transport, emissions, and disposal, inhalational exposures continue …
Update on irritant-induced occupational asthma.
Ronsmans S, Le Moual N, Dumas O. Ronsmans S, et al. Curr Opin Allergy Clin Immunol. 2023 Apr 1;23(2):63-69. doi: 10.1097/ACI.0000000000000884. Epub 2022 Dec 2. Curr Opin Allergy Clin Immunol. 2023. PMID: 36729951 Review.
Novel large epidemiological studies reported associations between chronic occupational exposure to irritants and current adult-onset asthma and poor asthma control, and with a specific asthma endotype characterized by neutrophilic inflammation and oxidative stress. …
Novel large epidemiological studies reported associations between chronic occupational exposure to irritants and current adult …
Irritants and asthma.
Casas L, Nemery B. Casas L, et al. Eur Respir J. 2014 Sep;44(3):562-4. doi: 10.1183/09031936.00090014. Eur Respir J. 2014. PMID: 25176947 Free article. No abstract available.
4,161 results