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Mutations in ribosomal protein L3 and 23S ribosomal RNA at the peptidyl transferase centre are associated with reduced susceptibility to tiamulin in Brachyspira spp. isolates.
Pringle M, Poehlsgaard J, Vester B, Long KS. Pringle M, et al. Among authors: vester b. Mol Microbiol. 2004 Dec;54(5):1295-306. doi: 10.1111/j.1365-2958.2004.04373.x. Mol Microbiol. 2004. PMID: 15554969
In a third group of clinical B. hyodysenteriae isolates, only a single mutation at amino acid 148 of ribosomal protein L3 was detected. ...
In a third group of clinical B. hyodysenteriae isolates, only a single mutation at amino acid 148 of ribosomal protein L3 was detecte …
Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain.
Hidalgo Á, Carvajal A, Vester B, Pringle M, Naharro G, Rubio P. Hidalgo Á, et al. Among authors: vester b. Antimicrob Agents Chemother. 2011 Jul;55(7):3330-7. doi: 10.1128/AAC.01749-10. Epub 2011 May 9. Antimicrob Agents Chemother. 2011. PMID: 21555771 Free PMC article.
MICs of tylosin, tiamulin, valnemulin, lincomycin, and tylvalosin were determined for 87 B. hyodysenteriae isolates recovered from 2008 to 2009 by broth dilution. ...An association between G2032A and high levels of tiamulin and lincomycin MICs was found, suggesting an incr …
MICs of tylosin, tiamulin, valnemulin, lincomycin, and tylvalosin were determined for 87 B. hyodysenteriae isolates recovered from 20 …
Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance.
Long KS, Munck C, Andersen TM, Schaub MA, Hobbie SN, Böttger EC, Vester B. Long KS, et al. Among authors: vester b. Antimicrob Agents Chemother. 2010 Nov;54(11):4705-13. doi: 10.1128/AAC.00644-10. Epub 2010 Aug 9. Antimicrob Agents Chemother. 2010. PMID: 20696869 Free PMC article.
Mutations in the bacterial ribosomal protein l3 and their association with antibiotic resistance.
Klitgaard RN, Ntokou E, Nørgaard K, Biltoft D, Hansen LH, Trædholm NM, Kongsted J, Vester B. Klitgaard RN, et al. Among authors: vester b. Antimicrob Agents Chemother. 2015;59(6):3518-28. doi: 10.1128/AAC.00179-15. Epub 2015 Apr 6. Antimicrob Agents Chemother. 2015. PMID: 25845869 Free PMC article.
Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket.
Long KS, Poehlsgaard J, Hansen LH, Hobbie SN, Böttger EC, Vester B. Long KS, et al. Among authors: vester b. Mol Microbiol. 2009 Mar;71(5):1218-27. doi: 10.1111/j.1365-2958.2009.06596.x. Epub 2009 Jan 16. Mol Microbiol. 2009. PMID: 19154331
Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center.
Long KS, Hansen LH, Jakobsen L, Vester B. Long KS, et al. Among authors: vester b. Antimicrob Agents Chemother. 2006 Apr;50(4):1458-62. doi: 10.1128/AAC.50.4.1458-1462.2006. Antimicrob Agents Chemother. 2006. PMID: 16569865 Free PMC article.
A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503.
Kehrenberg C, Schwarz S, Jacobsen L, Hansen LH, Vester B. Kehrenberg C, et al. Among authors: vester b. Mol Microbiol. 2005 Aug;57(4):1064-73. doi: 10.1111/j.1365-2958.2005.04754.x. Mol Microbiol. 2005. PMID: 16091044
The archaeon Haloarcula marismortui has few modifications in the central parts of its 23S ribosomal RNA.
Kirpekar F, Hansen LH, Rasmussen A, Poehlsgaard J, Vester B. Kirpekar F, et al. Among authors: vester b. J Mol Biol. 2005 May 6;348(3):563-73. doi: 10.1016/j.jmb.2005.03.009. J Mol Biol. 2005. PMID: 15826654
Resistance to the peptidyl transferase inhibitor tiamulin caused by mutation of ribosomal protein l3.
Bøsling J, Poulsen SM, Vester B, Long KS. Bøsling J, et al. Among authors: vester b. Antimicrob Agents Chemother. 2003 Sep;47(9):2892-6. doi: 10.1128/aac.47.9.2892-2896.2003. Antimicrob Agents Chemother. 2003. PMID: 12936991 Free PMC article.
The avilamycin resistance determinants AviRa and AviRb methylate 23S rRNA at the guanosine 2535 base and the uridine 2479 ribose.
Treede I, Jakobsen L, Kirpekar F, Vester B, Weitnauer G, Bechthold A, Douthwaite S. Treede I, et al. Among authors: vester b. Mol Microbiol. 2003 Jul;49(2):309-18. doi: 10.1046/j.1365-2958.2003.03558.x. Mol Microbiol. 2003. PMID: 12828631
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