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Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling.
Ogihara T, Chuang JC, Vestermark GL, Garmey JC, Ketchum RJ, Huang X, Brayman KL, Thorner MO, Repa JJ, Mirmira RG, Evans-Molina C. Ogihara T, et al. Among authors: vestermark gl. J Biol Chem. 2010 Feb 19;285(8):5392-404. doi: 10.1074/jbc.M109.064659. Epub 2009 Dec 11. J Biol Chem. 2010. PMID: 20007976 Free PMC article.
Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure.
Evans-Molina C, Robbins RD, Kono T, Tersey SA, Vestermark GL, Nunemaker CS, Garmey JC, Deering TG, Keller SR, Maier B, Mirmira RG. Evans-Molina C, et al. Among authors: vestermark gl. Mol Cell Biol. 2009 Apr;29(8):2053-67. doi: 10.1128/MCB.01179-08. Epub 2009 Feb 23. Mol Cell Biol. 2009. PMID: 19237535 Free PMC article.