Viazovkina E - Search Results

1

Oligonucleotides comprised of alternating 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides and D-2'-deoxyribonucleosides (2'F-ANA/DNA 'altimers') induce efficient RNA cleavage mediated by RNase H.

Min KL, Viazovkina E, Galarneau A, Parniak MA, Damha MJ. Min KL, et al. Among authors: viazovkina e. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2651-4. doi: 10.1016/s0960-894x(02)00439-0. Bioorg Med Chem Lett. 2002. PMID: 12182880

2

Synthesis of protected 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides.

Elzagheid MI, Viazovkina E, Damha MJ. Elzagheid MI, et al. Among authors: viazovkina e. Curr Protoc Nucleic Acid Chem. 2002 Nov;Chapter 1:Unit 1.7. doi: 10.1002/0471142700.nc0107s10. Curr Protoc Nucleic Acid Chem. 2002. PMID: 18428885

3

A new synthesis of 9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine (AraF-G).

Elzagheid MI, Viazovkina E, Damha MJ. Elzagheid MI, et al. Among authors: viazovkina e. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1339-42. doi: 10.1081/NCN-120022960. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565413

4

Synthesis and properties of oligonucleotide chimeras containing 5'-amino-2'-deoxy-2'-fluoroarabinonucleosides.

Viazovkina E, Min KL, Galarneau A, Damha MJ. Viazovkina E, et al. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1335-8. doi: 10.1081/ncn-120022959. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565412

5

Antisense inhibition of Flk-1 by oligonucleotides composed of 2'-deoxy-2'-fluoro-beta-D-arabino- and 2'-deoxy-nucleosides.

Lacombe J, Viazovkina E, Bernatchez PN, Galarneau A, Damha MJ, Sirois MG. Lacombe J, et al. Among authors: viazovkina e. Can J Physiol Pharmacol. 2002 Oct;80(10):951-61. doi: 10.1139/y02-123. Can J Physiol Pharmacol. 2002. PMID: 12450061

6

Potent gene-specific inhibitory properties of mixed-backbone antisense oligonucleotides comprised of 2'-deoxy-2'-fluoro-D-arabinose and 2'-deoxyribose nucleotides.

Lok CN, Viazovkina E, Min KL, Nagy E, Wilds CJ, Damha MJ, Parniak MA. Lok CN, et al. Among authors: viazovkina e. Biochemistry. 2002 Mar 12;41(10):3457-67. doi: 10.1021/bi0115075. Biochemistry. 2002. PMID: 11876654

7

Solid-phase synthesis of 2'-deoxy-2'-fluoro- beta-D-oligoarabinonucleotides (2'F-ANA) and their phosphorothioate derivatives.

Viazovkina E, Mangos MM, Elzagheid MI, Damha MJ. Viazovkina E, et al. Curr Protoc Nucleic Acid Chem. 2002 Nov;Chapter 4:Unit 4.15. doi: 10.1002/0471142700.nc0415s10. Curr Protoc Nucleic Acid Chem. 2002. PMID: 18428897

8

Efficient RNase H-directed cleavage of RNA promoted by antisense DNA or 2'F-ANA constructs containing acyclic nucleotide inserts.

Mangos MM, Min KL, Viazovkina E, Galarneau A, Elzagheid MI, Parniak MA, Damha MJ. Mangos MM, et al. Among authors: viazovkina e. J Am Chem Soc. 2003 Jan 22;125(3):654-61. doi: 10.1021/ja025557o. J Am Chem Soc. 2003. PMID: 12526664

9

Synthesis and physicochemical properties of 2'-deoxy-2',2''-difluoro-beta-D-ribofuranosyl and 2'-deoxy-2',2''-difluoro-alpha-D-ribofuranosyl oligonucleotides.

Viazovkina E, Mangos MM, Damha MJ. Viazovkina E, et al. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1251-4. doi: 10.1081/NCN-120022848. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565392

10

2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (2'F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencing.

Kalota A, Karabon L, Swider CR, Viazovkina E, Elzagheid M, Damha MJ, Gewirtz AM. Kalota A, et al. Among authors: viazovkina e. Nucleic Acids Res. 2006 Jan 18;34(2):451-61. doi: 10.1093/nar/gkj455. Print 2006. Nucleic Acids Res. 2006. PMID: 16421272 Free PMC article.

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