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Treatment of endometriosis-related pain: options and outcomes.
Somigliana E, Vigano P, Barbara G, Vercellini P. Somigliana E, et al. Front Biosci (Elite Ed). 2009 Jun 1;1:455-65. doi: 10.2741/e41. Front Biosci (Elite Ed). 2009. PMID: 19482659 Review.
Deficient antiendometrium lymphocyte-mediated cytotoxicity in patients with endometriosis.
Viganò P, Vercellini P, Di Blasio AM, Colombo A, Candiani GB, Vignali M. Viganò P, et al. Fertil Steril. 1991 Nov;56(5):894-9. doi: 10.1016/s0015-0282(16)54661-5. Fertil Steril. 1991. PMID: 1936324
RESULTS: The lymphocyte response in the presence of stromal cell antigens was significantly lower (P less than 0.02) in disease-affected women when compared with that obtained in controls (2.89 +/- 0.87 and 7.64 +/- 1.66, respectively). ...
RESULTS: The lymphocyte response in the presence of stromal cell antigens was significantly lower (P less than 0.02) in disease-affec …
Modulation of NK cell lytic function by endometrial secretory factors: potential role in endometriosis.
Somigliana E, Viganò P, Gaffuri B, Candiani M, Busacca M, Di Blasio AM, Vignali M. Somigliana E, et al. Am J Reprod Immunol. 1996 Nov;36(5):295-300. doi: 10.1111/j.1600-0897.1996.tb00179.x. Am J Reprod Immunol. 1996. PMID: 8955507

RESULTS: Media conditioned by the overall endometrial stromal cultures exerted a significant suppressive effect (P < 0.001) on NK cell function when compared to control NK fractions (mean percentage of cytotoxicity +/- SEM 17.46 +/- 2.8 and 29.41 +/- 1.49, respectively)

RESULTS: Media conditioned by the overall endometrial stromal cultures exerted a significant suppressive effect (P < 0.001) on NK

Expression of intercellular adhesion molecule (ICAM)-1 mRNA and protein is enhanced in endometriosis versus endometrial stromal cells in culture.
Viganò P, Gaffuri B, Somigliana E, Busacca M, Di Blasio AM, Vignali M. Viganò P, et al. Mol Hum Reprod. 1998 Dec;4(12):1150-6. doi: 10.1093/molehr/4.12.1150. Mol Hum Reprod. 1998. PMID: 9872366
Moreover, ectopic cells demonstrated a significant overexpression of ICAM-1 protein in both its cell-bound and soluble form (sICAM-1) (P < 0.05). ...
Moreover, ectopic cells demonstrated a significant overexpression of ICAM-1 protein in both its cell-bound and soluble form (sICAM-1) (P
Endometrial release of soluble intercellular adhesion molecule 1 and endometriosis: relationship to the extent of the disease.
Viganò P, Somigliana E, Gaffuri B, Santorsola R, Busacca M, Vignali M. Viganò P, et al. Obstet Gynecol. 2000 Jan;95(1):115-8. Obstet Gynecol. 2000. PMID: 10636513

RESULTS: Endometrial release of soluble intercellular adhesion molecule 1 directly correlated with number of implants (r = .64, P < .005) and score for implants (r = .61, P < .005). ...Soluble intercellular adhesion molecule 1 shed by endometrium did not corre

RESULTS: Endometrial release of soluble intercellular adhesion molecule 1 directly correlated with number of implants (r = .64, P &lt …
Expression of GnRH receptor gene in human ectopic endometrial cells and inhibition of their proliferation by leuprolide acetate.
Borroni R, Di Blasio AM, Gaffuri B, Santorsola R, Busacca M, Viganò P, Vignali M. Borroni R, et al. Mol Cell Endocrinol. 2000 Jan 25;159(1-2):37-43. doi: 10.1016/s0303-7207(99)00199-9. Mol Cell Endocrinol. 2000. PMID: 10687850
Use of knockout transgenic mice in the study of endometriosis: insights from mice lacking beta(2)-microglobulin and interleukin-12p40.
Somigliana E, Viganò P, Filardo P, Candiani M, Vignali M, Panina-Bordignon P. Somigliana E, et al. Fertil Steril. 2001 Jan;75(1):203-6. doi: 10.1016/s0015-0282(00)01659-9. Fertil Steril. 2001. PMID: 11163839
Induction of endometriosis in the mouse inhibits spleen leukocyte function.
Somigliana E, Viganò P, Zingrillo B, Ranieri S, Filardo P, Candiani M, Vignali M. Somigliana E, et al. Acta Obstet Gynecol Scand. 2001 Mar;80(3):200-5. doi: 10.1034/j.1600-0412.2001.080003200.x. Acta Obstet Gynecol Scand. 2001. PMID: 11207484
RESULTS: A significant inhibition of spleenocyte growth was demonstrated in mice in which endometriosis was induced (36156+/-3061 cpm) compared to control animals (47172+/-3210 cpm; p<0.05). Moreover, a significant inverse correlation was found between spleenocyte proli …
RESULTS: A significant inhibition of spleenocyte growth was demonstrated in mice in which endometriosis was induced (36156+/-3061 cpm) compa …
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