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Acute Treatment with the M-Channel (Kv7, KCNQ) Opener Retigabine Reduces the Long-Term Effects of Repetitive Blast Traumatic Brain Injuries.
Vigil FA, Belchior H, Bugay V, Bazaldua II, Stoja A, Dantas DC, Chun SH, Farmer A, Bozdemir E, Holstein DM, Cavazos JE, Lechleiter JD, Brenner R, Shapiro MS. Vigil FA, et al. Neurotherapeutics. 2023 Apr;20(3):853-869. doi: 10.1007/s13311-023-01361-9. Epub 2023 Mar 28. Neurotherapeutics. 2023. PMID: 36976493 Free PMC article.
Neuroprotective Roles of the Adenosine A3 Receptor Agonist AST-004 in Mouse Model of Traumatic Brain Injury.
Bozdemir E, Vigil FA, Chun SH, Espinoza L, Bugay V, Khoury SM, Holstein DM, Stoja A, Lozano D, Tunca C, Sprague SM, Cavazos JE, Brenner R, Liston TE, Shapiro MS, Lechleiter JD. Bozdemir E, et al. Among authors: vigil fa. Neurotherapeutics. 2021 Oct;18(4):2707-2721. doi: 10.1007/s13311-021-01113-7. Epub 2021 Oct 4. Neurotherapeutics. 2021. PMID: 34608616 Free PMC article.
Prevention of brain damage after traumatic brain injury by pharmacological enhancement of KCNQ (Kv7, "M-type") K+ currents in neurons.
Vigil FA, Bozdemir E, Bugay V, Chun SH, Hobbs M, Sanchez I, Hastings SD, Veraza RJ, Holstein DM, Sprague SM, M Carver C, Cavazos JE, Brenner R, Lechleiter JD, Shapiro MS. Vigil FA, et al. J Cereb Blood Flow Metab. 2020 Jun;40(6):1256-1273. doi: 10.1177/0271678X19857818. Epub 2019 Jul 4. J Cereb Blood Flow Metab. 2020. PMID: 31272312 Free PMC article.
Spatial cognitive deficits in an animal model of Wernicke-Korsakoff syndrome are related to changes in thalamic VDAC protein concentrations.
Bueno KO, de Souza Resende L, Ribeiro AF, Dos Santos DM, Gonçalves EC, Vigil FA, de Oliveira Silva IF, Ferreira LF, de Castro Pimenta AM, Ribeiro AM. Bueno KO, et al. Among authors: vigil fa. Neuroscience. 2015 May 21;294:29-37. doi: 10.1016/j.neuroscience.2015.03.001. Epub 2015 Mar 9. Neuroscience. 2015. PMID: 25766938