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Insights into the processing of MHC class I ligands gained from the study of human tumor epitopes.
Vigneron N, Van den Eynde BJ. Vigneron N, et al. Cell Mol Life Sci. 2011 May;68(9):1503-20. doi: 10.1007/s00018-011-0658-x. Epub 2011 Mar 9. Cell Mol Life Sci. 2011. PMID: 21387143 Review.
Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes.
Ebstein F, Textoris-Taube K, Keller C, Golnik R, Vigneron N, Van den Eynde BJ, Schuler-Thurner B, Schadendorf D, Lorenz FK, Uckert W, Urban S, Lehmann A, Albrecht-Koepke N, Janek K, Henklein P, Niewienda A, Kloetzel PM, Mishto M. Ebstein F, et al. Among authors: vigneron n. Sci Rep. 2016 Apr 6;6:24032. doi: 10.1038/srep24032. Sci Rep. 2016. PMID: 27049119 Free PMC article.
A peptide derived from melanocytic protein gp100 and presented by HLA-B35 is recognized by autologous cytolytic T lymphocytes on melanoma cells.
Vigneron N, Ooms A, Morel S, Ma W, Degiovanni G, Van den Eynde BJ. Vigneron N, et al. Tissue Antigens. 2005 Feb;65(2):156-62. doi: 10.1111/j.1399-0039.2005.00365.x. Tissue Antigens. 2005. PMID: 15713214
[Antigenic peptides for peptide splicing in the proteosome].
Vigneron N. Vigneron N. Bull Mem Acad R Med Belg. 2010;165(5-6):305-9. Bull Mem Acad R Med Belg. 2010. PMID: 21513118 French.
An antigen produced by splicing of noncontiguous peptides in the reverse order.
Warren EH, Vigneron NJ, Gavin MA, Coulie PG, Stroobant V, Dalet A, Tykodi SS, Xuereb SM, Mito JK, Riddell SR, Van den Eynde BJ. Warren EH, et al. Science. 2006 Sep 8;313(5792):1444-7. doi: 10.1126/science.1130660. Science. 2006. PMID: 16960008
Differences in the production of spliced antigenic peptides by the standard proteasome and the immunoproteasome.
Dalet A, Stroobant V, Vigneron N, Van den Eynde BJ. Dalet A, et al. Among authors: vigneron n. Eur J Immunol. 2011 Jan;41(1):39-46. doi: 10.1002/eji.201040750. Epub 2010 Dec 9. Eur J Immunol. 2011. PMID: 21182075
Cytosolic Processing Governs TAP-Independent Presentation of a Critical Melanoma Antigen.
Vigneron N, Ferrari V, Van den Eynde BJ, Cresswell P, Leonhardt RM. Vigneron N, et al. J Immunol. 2018 Oct 1;201(7):1875-1888. doi: 10.4049/jimmunol.1701479. Epub 2018 Aug 22. J Immunol. 2018. PMID: 30135181 Free PMC article.
C19orf48 encodes a minor histocompatibility antigen recognized by CD8+ cytotoxic T cells from renal cell carcinoma patients.
Tykodi SS, Fujii N, Vigneron N, Lu SM, Mito JK, Miranda MX, Chou J, Voong LN, Thompson JA, Sandmaier BM, Cresswell P, Van den Eynde B, Riddell SR, Warren EH. Tykodi SS, et al. Among authors: vigneron n. Clin Cancer Res. 2008 Aug 15;14(16):5260-9. doi: 10.1158/1078-0432.CCR-08-0028. Clin Cancer Res. 2008. PMID: 18698046 Free PMC article.
A MAGE-C2 antigenic peptide processed by the immunoproteasome is recognized by cytolytic T cells isolated from a melanoma patient after successful immunotherapy.
Ma W, Vigneron N, Chapiro J, Stroobant V, Germeau C, Boon T, Coulie PG, Van den Eynde BJ. Ma W, et al. Among authors: vigneron n. Int J Cancer. 2011 Nov 15;129(10):2427-34. doi: 10.1002/ijc.25911. Epub 2011 Apr 20. Int J Cancer. 2011. PMID: 21207413
Identifying Antigens Recognized by Cytolytic T Lymphocytes on Tumors.
Vigneron N, Stroobant V, Ma W, Michaux A, Van den Eynde BJ. Vigneron N, et al. Methods Mol Biol. 2019;1988:159-186. doi: 10.1007/978-1-4939-9450-2_13. Methods Mol Biol. 2019. PMID: 31147940
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