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The Pl(A2) polymorphism of integrin beta(3) enhances outside-in signaling and adhesive functions.
Vijayan KV, Goldschmidt-Clermont PJ, Roos C, Bray PF. Vijayan KV, et al. J Clin Invest. 2000 Mar;105(6):793-802. doi: 10.1172/JCI6982. J Clin Invest. 2000. PMID: 10727448 Free PMC article.
Distinct roles for the α , β and γ1 isoforms of protein phosphatase 1 in the outside-in αIIbβ3 integrin signalling-dependent functions.
Alrehani N, Pradhan S, Khatlani T, Kailasam L, Vijayan KV. Alrehani N, et al. Among authors: vijayan kv. Thromb Haemost. 2013 Jan;109(1):118-26. doi: 10.1160/TH12-04-0237. Epub 2012 Nov 29. Thromb Haemost. 2013. PMID: 23197154 Free PMC article.
A Novel Interaction of the Catalytic Subunit of Protein Phosphatase 2A with the Adaptor Protein CIN85 Suppresses Phosphatase Activity and Facilitates Platelet Outside-in αIIbβ3 Integrin Signaling.
Khatlani T, Pradhan S, Da Q, Shaw T, Buchman VL, Cruz MA, Vijayan KV. Khatlani T, et al. Among authors: vijayan kv. J Biol Chem. 2016 Aug 12;291(33):17360-8. doi: 10.1074/jbc.M115.704296. Epub 2016 Jun 22. J Biol Chem. 2016. PMID: 27334924 Free PMC article.
Glutathione regulates integrin alpha(IIb)beta(3)-mediated cell adhesion under flow conditions.
Ball C, Vijayan KV, Nguyen T, Anthony K, Bray PF, Essex DW, Dong JF. Ball C, et al. Among authors: vijayan kv. Thromb Haemost. 2008 Nov;100(5):857-63. Thromb Haemost. 2008. PMID: 18989530
Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling.
Gushiken FC, Patel V, Liu Y, Pradhan S, Bergeron AL, Peng Y, Vijayan KV. Gushiken FC, et al. Among authors: vijayan kv. J Biol Chem. 2008 May 9;283(19):12862-9. doi: 10.1074/jbc.M708804200. Epub 2008 Mar 11. J Biol Chem. 2008. PMID: 18334487 Free PMC article.
The Pro33 isoform of integrin beta3 enhances outside-in signaling in human platelets by regulating the activation of serine/threonine phosphatases.
Vijayan KV, Liu Y, Sun W, Ito M, Bray PF. Vijayan KV, et al. J Biol Chem. 2005 Jun 10;280(23):21756-62. doi: 10.1074/jbc.M500872200. Epub 2005 Apr 11. J Biol Chem. 2005. PMID: 15826939
Protein phosphatase 1 associates with the integrin alphaIIb subunit and regulates signaling.
Vijayan KV, Liu Y, Li TT, Bray PF. Vijayan KV, et al. J Biol Chem. 2004 Aug 6;279(32):33039-42. doi: 10.1074/jbc.C400239200. Epub 2004 Jun 17. J Biol Chem. 2004. PMID: 15205468
Enhanced activation of mitogen-activated protein kinase and myosin light chain kinase by the Pro33 polymorphism of integrin beta 3.
Vijayan KV, Liu Y, Dong JF, Bray PF. Vijayan KV, et al. J Biol Chem. 2003 Feb 7;278(6):3860-7. doi: 10.1074/jbc.M208680200. Epub 2002 Nov 29. J Biol Chem. 2003. PMID: 12460991
PlA polymorphism of integrin beta 3 differentially modulates cellular migration on extracellular matrix proteins.
Sajid M, Vijayan KV, Souza S, Bray PF. Sajid M, et al. Among authors: vijayan kv. Arterioscler Thromb Vasc Biol. 2002 Dec 1;22(12):1984-9. doi: 10.1161/01.atv.0000043664.48689.7f. Arterioscler Thromb Vasc Biol. 2002. PMID: 12482823
The β isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in αII b β3 integrin signaling.
Khatlani T, Pradhan S, Da Q, Gushiken FC, Bergeron AL, Langlois KW, Molkentin JD, Rumbaut RE, Vijayan KV. Khatlani T, et al. Among authors: vijayan kv. J Thromb Haemost. 2014 Dec;12(12):2089-101. doi: 10.1111/jth.12761. Epub 2014 Nov 15. J Thromb Haemost. 2014. PMID: 25330904 Free PMC article.
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