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Xenoreceptors CAR and PXR activation and consequences on lipid metabolism, glucose homeostasis, and inflammatory response.
Moreau A, Vilarem MJ, Maurel P, Pascussi JM. Moreau A, et al. Among authors: vilarem mj. Mol Pharm. 2008 Jan-Feb;5(1):35-41. doi: 10.1021/mp700103m. Epub 2007 Dec 27. Mol Pharm. 2008. PMID: 18159929 Review.
Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3).
Breuker C, Moreau A, Lakhal L, Tamasi V, Parmentier Y, Meyer U, Maurel P, Lumbroso S, Vilarem MJ, Pascussi JM. Breuker C, et al. Among authors: vilarem mj. Endocrinology. 2010 Apr;151(4):1653-61. doi: 10.1210/en.2009-1435. Epub 2010 Feb 25. Endocrinology. 2010. PMID: 20185760
A novel pregnane X receptor and S14-mediated lipogenic pathway in human hepatocyte.
Moreau A, Téruel C, Beylot M, Albalea V, Tamasi V, Umbdenstock T, Parmentier Y, Sa-Cunha A, Suc B, Fabre JM, Navarro F, Ramos J, Meyer U, Maurel P, Vilarem MJ, Pascussi JM. Moreau A, et al. Among authors: vilarem mj. Hepatology. 2009 Jun;49(6):2068-79. doi: 10.1002/hep.22907. Hepatology. 2009. PMID: 19437491
[[Inflammation and drug metabolism: NF-kappB and the CAR and PXR xeno-receptors].
Pascussi JM, Vilarem MJ. Pascussi JM, et al. Among authors: vilarem mj. Med Sci (Paris). 2008 Mar;24(3):301-5. doi: 10.1051/medsci/2008243301. Med Sci (Paris). 2008. PMID: 18334180 Free article. Review. French.
Transcriptional analysis of the orphan nuclear receptor constitutive androstane receptor (NR1I3) gene promoter: identification of a distal glucocorticoid response element.
Pascussi JM, Busson-Le Coniat M, Maurel P, Vilarem MJ. Pascussi JM, et al. Mol Endocrinol. 2003 Jan;17(1):42-55. doi: 10.1210/me.2002-0244. Mol Endocrinol. 2003. PMID: 12511605
Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor.
Gerbal-Chaloin S, Daujat M, Pascussi JM, Pichard-Garcia L, Vilarem MJ, Maurel P. Gerbal-Chaloin S, et al. J Biol Chem. 2002 Jan 4;277(1):209-17. doi: 10.1074/jbc.M107228200. Epub 2001 Oct 25. J Biol Chem. 2002. PMID: 11679585
The tangle of nuclear receptors that controls xenobiotic metabolism and transport: crosstalk and consequences.
Pascussi JM, Gerbal-Chaloin S, Duret C, Daujat-Chavanieu M, Vilarem MJ, Maurel P. Pascussi JM, et al. Among authors: vilarem mj. Annu Rev Pharmacol Toxicol. 2008;48:1-32. doi: 10.1146/annurev.pharmtox.47.120505.105349. Annu Rev Pharmacol Toxicol. 2008. PMID: 17608617 Review.
Constitutive androstane receptor-vitamin D receptor crosstalk: consequence on CYP24 gene expression.
Moreau A, Maurel P, Vilarem MJ, Pascussi JM. Moreau A, et al. Among authors: vilarem mj. Biochem Biophys Res Commun. 2007 Aug 17;360(1):76-82. doi: 10.1016/j.bbrc.2007.06.003. Epub 2007 Jun 13. Biochem Biophys Res Commun. 2007. PMID: 17585873
Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.
Duret C, Daujat-Chavanieu M, Pascussi JM, Pichard-Garcia L, Balaguer P, Fabre JM, Vilarem MJ, Maurel P, Gerbal-Chaloin S. Duret C, et al. Mol Pharmacol. 2006 Jul;70(1):329-39. doi: 10.1124/mol.105.022046. Epub 2006 Apr 11. Mol Pharmacol. 2006. PMID: 16608920
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