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Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization.
Singh NA, Otto JF, Dahle EJ, Pappas C, Leslie JD, Vilaythong A, Noebels JL, White HS, Wilcox KS, Leppert MF. Singh NA, et al. Among authors: vilaythong a. J Physiol. 2008 Jul 15;586(14):3405-23. doi: 10.1113/jphysiol.2008.154971. Epub 2008 May 15. J Physiol. 2008. PMID: 18483067 Free PMC article.
Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture.
Chen C, Westenbroek RE, Xu X, Edwards CA, Sorenson DR, Chen Y, McEwen DP, O'Malley HA, Bharucha V, Meadows LS, Knudsen GA, Vilaythong A, Noebels JL, Saunders TL, Scheuer T, Shrager P, Catterall WA, Isom LL. Chen C, et al. Among authors: vilaythong a. J Neurosci. 2004 Apr 21;24(16):4030-42. doi: 10.1523/JNEUROSCI.4139-03.2004. J Neurosci. 2004. PMID: 15102918 Free PMC article.