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Targeting the Fas/FasL signaling pathway in cancer therapy.

Villa-Morales M, Fernández-Piqueras J. Villa-Morales M, et al. Expert Opin Ther Targets. 2012 Jan;16(1):85-101. doi: 10.1517/14728222.2011.628937. Epub 2012 Jan 12. Expert Opin Ther Targets. 2012. PMID: 22239437 Review.

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Functional Fas (Cd95/Apo-1) promoter polymorphisms in inbred mouse strains exhibiting different susceptibility to gamma-radiation-induced thymic lymphoma.

Villa-Morales M, Santos J, Fernández-Piqueras J. Villa-Morales M, et al. Oncogene. 2006 Mar 30;25(14):2022-9. doi: 10.1038/sj.onc.1209234. Oncogene. 2006. PMID: 16301997

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A role for the Fas/FasL system in modulating genetic susceptibility to T-cell lymphoblastic lymphomas.

Villa-Morales M, Santos J, Pérez-Gómez E, Quintanilla M, Fernández-Piqueras J. Villa-Morales M, et al. Cancer Res. 2007 Jun 1;67(11):5107-16. doi: 10.1158/0008-5472.CAN-06-4006. Cancer Res. 2007. PMID: 17545588

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A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis.

Pérez-Gómez E, Villa-Morales M, Santos J, Fernández-Piqueras J, Gamallo C, Dotor J, Bernabéu C, Quintanilla M. Pérez-Gómez E, et al. Cancer Res. 2007 Nov 1;67(21):10268-77. doi: 10.1158/0008-5472.CAN-07-1348. Cancer Res. 2007. PMID: 17974968

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A role for stroma-derived annexin A1 as mediator in the control of genetic susceptibility to T-cell lymphoblastic malignancies through prostaglandin E2 secretion.

Santos J, González-Sánchez L, Matabuena-Deyzaguirre M, Villa-Morales M, Cozar P, López-Nieva P, Fernández-Navarro P, Fresno M, Díaz-Muñoz MD, Guenet JL, Montagutelli X, Fernández-Piqueras J. Santos J, et al. Cancer Res. 2009 Mar 15;69(6):2577-87. doi: 10.1158/0008-5472.CAN-08-1821. Epub 2009 Feb 24. Cancer Res. 2009. PMID: 19244132

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Modulation of the Fas-apoptosis-signalling pathway by functional polymorphisms at Fas, FasL and Fadd and their implication in T-cell lymphoblastic lymphoma susceptibility.

Villa-Morales M, González-Gugel E, Shahbazi MN, Santos J, Fernández-Piqueras J. Villa-Morales M, et al. Carcinogenesis. 2010 Dec;31(12):2165-71. doi: 10.1093/carcin/bgq201. Epub 2010 Oct 1. Carcinogenesis. 2010. PMID: 20889682

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Down-regulation of specific miRNAs enhances the expression of the gene Smoothened and contributes to T-cell lymphoblastic lymphoma development.

González-Gugel E, Villa-Morales M, Santos J, Bueno MJ, Malumbres M, Rodríguez-Pinilla SM, Piris MÁ, Fernández-Piqueras J. González-Gugel E, et al. Carcinogenesis. 2013 Apr;34(4):902-8. doi: 10.1093/carcin/bgs404. Epub 2013 Jan 3. Carcinogenesis. 2013. PMID: 23288923

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FAS system deregulation in T-cell lymphoblastic lymphoma.

Villa-Morales M, Cobos MA, González-Gugel E, Álvarez-Iglesias V, Martínez B, Piris MA, Carracedo A, Benítez J, Fernández-Piqueras J. Villa-Morales M, et al. Cell Death Dis. 2014 Mar 6;5(3):e1110. doi: 10.1038/cddis.2014.83. Cell Death Dis. 2014. PMID: 24603338 Free PMC article.

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Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer.

Pérez-Gómez E, Andradas C, Blasco-Benito S, Caffarel MM, García-Taboada E, Villa-Morales M, Moreno E, Hamann S, Martín-Villar E, Flores JM, Wenners A, Alkatout I, Klapper W, Röcken C, Bronsert P, Stickeler E, Staebler A, Bauer M, Arnold N, Soriano J, Pérez-Martínez M, Megías D, Moreno-Bueno G, Ortega-Gutiérrez S, Artola M, Vázquez-Villa H, Quintanilla M, Fernández-Piqueras J, Canela EI, McCormick PJ, Guzmán M, Sánchez C. Pérez-Gómez E, et al. Among authors: villa morales m. J Natl Cancer Inst. 2015 Apr 8;107(6):djv077. doi: 10.1093/jnci/djv077. Print 2015 Jun. J Natl Cancer Inst. 2015. PMID: 25855725 Free article.

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Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma.

Marín-Rubio JL, de Arriba MC, Cobos-Fernández MA, González-Sánchez L, Ors I, Sastre I, Fernández-Piqueras J, Villa-Morales M. Marín-Rubio JL, et al. Among authors: villa morales m. Oncotarget. 2016 Sep 20;7(38):61485-61499. doi: 10.18632/oncotarget.11370. Oncotarget. 2016. PMID: 27556297 Free PMC article.

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