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PGC-1β promotes enterocyte lifespan and tumorigenesis in the intestine.
Bellafante E, Morgano A, Salvatore L, Murzilli S, Di Tullio G, D'Orazio A, Latorre D, Villani G, Moschetta A. Bellafante E, et al. Among authors: villani g. Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4523-31. doi: 10.1073/pnas.1415279111. Epub 2014 Oct 6. Proc Natl Acad Sci U S A. 2014. PMID: 25288742 Free PMC article.
A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels.
Peserico A, Chiacchiera F, Grossi V, Matrone A, Latorre D, Simonatto M, Fusella A, Ryall JG, Finley LW, Haigis MC, Villani G, Puri PL, Sartorelli V, Simone C. Peserico A, et al. Among authors: villani g. Cell Mol Life Sci. 2013 Jun;70(11):2015-29. doi: 10.1007/s00018-012-1244-6. Epub 2013 Jan 3. Cell Mol Life Sci. 2013. PMID: 23283301
Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) is a metabolic regulator of intestinal epithelial cell fate.
D'Errico I, Salvatore L, Murzilli S, Lo Sasso G, Latorre D, Martelli N, Egorova AV, Polishuck R, Madeyski-Bengtson K, Lelliott C, Vidal-Puig AJ, Seibel P, Villani G, Moschetta A. D'Errico I, et al. Among authors: villani g. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6603-8. doi: 10.1073/pnas.1016354108. Epub 2011 Apr 5. Proc Natl Acad Sci U S A. 2011. PMID: 21467224 Free PMC article.
Bax is necessary for PGC1α pro-apoptotic effect in colorectal cancer cells.
D'Errico I, Lo Sasso G, Salvatore L, Murzilli S, Martelli N, Cristofaro M, Latorre D, Villani G, Moschetta A. D'Errico I, et al. Among authors: villani g. Cell Cycle. 2011 Sep 1;10(17):2937-45. doi: 10.4161/cc.10.17.16791. Epub 2011 Sep 1. Cell Cycle. 2011. PMID: 21862870
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