Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

719 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Pathogenesis of hepatocellular carcinoma and molecular therapies.
Mínguez B, Tovar V, Chiang D, Villanueva A, Llovet JM. Mínguez B, et al. Curr Opin Gastroenterol. 2009 May;25(3):186-94. doi: 10.1097/MOG.0b013e32832962a1. Curr Opin Gastroenterol. 2009. PMID: 19387255 Review.
RECENT FINDINGS: The discovery of sorafenib, a multikinase inhibitor, as a treatment with survival benefits in patients with advanced HCC, has become a major breakthrough in the clinical management of HCC. ...At last, a molecular classification of HCC …
RECENT FINDINGS: The discovery of sorafenib, a multikinase inhibitor, as a treatment with survival benefits in patients with a …
Safety of percutaneous ethanol injection as neoadjuvant therapy for hepatocellular carcinoma in waiting list liver transplant candidates.
Castroagudín JF, Delgado M, Villanueva A, Bustamante M, Martínez J, Otero E, Tomé S, Martínez SM, Segade FR, Conde R, Dominguez-Muñoz E, Varo E. Castroagudín JF, et al. Transplant Proc. 2005 Nov;37(9):3871-3. doi: 10.1016/j.transproceed.2005.09.168. Transplant Proc. 2005. PMID: 16386568
Orthotopic liver transplantation (OLT) as therapy of hepatocellular carcinoma (HCC) improves the survival of a selected group of patients. ...PATIENTS AND METHODS: During a 60-month period, 34 patients (27 men, overall mean age of 58.5 years, range 41-67) with HCC, …
Orthotopic liver transplantation (OLT) as therapy of hepatocellular carcinoma (HCC) improves the survival of a selected group of pati …
A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.
Llovet JM, Chen Y, Wurmbach E, Roayaie S, Fiel MI, Schwartz M, Thung SN, Khitrov G, Zhang W, Villanueva A, Battiston C, Mazzaferro V, Bruix J, Waxman S, Friedman SL. Llovet JM, et al. Gastroenterology. 2006 Dec;131(6):1758-67. doi: 10.1053/j.gastro.2006.09.014. Epub 2006 Sep 19. Gastroenterology. 2006. PMID: 17087938
Logistic regression analysis identified a 3-gene set including GPC3 (18-fold increase in HCC, P = .01), LYVE1 (12-fold decrease in HCC, P = .0001), and survivin (2.2-fold increase in HCC, P = .02), which had a discriminative accuracy of 94%. ...CONCLUSIONS: Molecula …
Logistic regression analysis identified a 3-gene set including GPC3 (18-fold increase in HCC, P = .01), LYVE1 (12-fold decrease in HC …
Genomics and signaling pathways in hepatocellular carcinoma.
Villanueva A, Newell P, Chiang DY, Friedman SL, Llovet JM. Villanueva A, et al. Semin Liver Dis. 2007 Feb;27(1):55-76. doi: 10.1055/s-2006-960171. Semin Liver Dis. 2007. PMID: 17295177 Review.
Hepatocellular carcinoma (HCC) is a leading cause of death among cirrhotic patients and has become a major health problem in developed countries. ...Nonetheless, a comprehensive genomic analysis of HCC samples using high-resolution platforms in precisely anno …
Hepatocellular carcinoma (HCC) is a leading cause of death among cirrhotic patients and has become a major health problem in d …
[Cell biology and genetics in liver cancer].
Tovar V, Villanueva A, Llovet JM. Tovar V, et al. Gastroenterol Hepatol. 2007 Jun-Jul;30(6):360-9. doi: 10.1157/13107573. Gastroenterol Hepatol. 2007. PMID: 17662221 Review. Spanish.
Hepatocellular carcinoma (HCC) is the main cause of death in cirrhotic patients and has become a major health problem in developed countries. ...The most widely accepted hypothesis suggests that numerous genomic alterations in the hepatocyte cells lead to a neoplast …
Hepatocellular carcinoma (HCC) is the main cause of death in cirrhotic patients and has become a major health problem in developed co …
Experimental models of hepatocellular carcinoma.
Newell P, Villanueva A, Friedman SL, Koike K, Llovet JM. Newell P, et al. J Hepatol. 2008 May;48(5):858-79. doi: 10.1016/j.jhep.2008.01.008. Epub 2008 Jan 30. J Hepatol. 2008. PMID: 18314222 Free PMC article. Review.
Hepatocellular carcinoma (HCC) is a common and deadly cancer whose pathogenesis is incompletely understood. Comparative genomic studies from human HCC samples have classified HCCs into different molecular subgroups; yet, the unifying feature of this tumor is its propensity …
Hepatocellular carcinoma (HCC) is a common and deadly cancer whose pathogenesis is incompletely understood. Comparative genomic studi …
Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma.
Yea S, Narla G, Zhao X, Garg R, Tal-Kremer S, Hod E, Villanueva A, Loke J, Tarocchi M, Akita K, Shirasawa S, Sasazuki T, Martignetti JA, Llovet JM, Friedman SL. Yea S, et al. Gastroenterology. 2008 May;134(5):1521-31. doi: 10.1053/j.gastro.2008.02.015. Epub 2008 Feb 13. Gastroenterology. 2008. PMID: 18471523 Free PMC article.
Dysregulation of alternative splicing underlies a number of human diseases, yet its contribution to liver cancer has not been explored fully. ...RESULTS: In 67 human HCCs, there is a significant correlation between activated Ras signaling and increased KLF6 alternat …
Dysregulation of alternative splicing underlies a number of human diseases, yet its contribution to liver cancer has not been explore …
Linking molecular classification of hepatocellular carcinoma and personalized medicine: preliminary steps.
Villanueva A, Toffanin S, Llovet JM. Villanueva A, et al. Curr Opin Oncol. 2008 Jul;20(4):444-53. doi: 10.1097/CCO.0b013e328302c9e9. Curr Opin Oncol. 2008. PMID: 18525342 Free PMC article. Review.
Obtaining a molecular classification of hepatocellular carcinoma, however, remains a striking challenge. This review summarizes the molecular classifications of hepatocellular carcinoma reported so far, analyzes the status of targeted therapies tested in clinical tr …
Obtaining a molecular classification of hepatocellular carcinoma, however, remains a striking challenge. This review summarize …
719 results
Jump to page
Feedback