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Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells.
Roesch A, Vultur A, Bogeski I, Wang H, Zimmermann KM, Speicher D, Körbel C, Laschke MW, Gimotty PA, Philipp SE, Krause E, Pätzold S, Villanueva J, Krepler C, Fukunaga-Kalabis M, Hoth M, Bastian BC, Vogt T, Herlyn M. Roesch A, et al. Among authors: villanueva j. Cancer Cell. 2013 Jun 10;23(6):811-25. doi: 10.1016/j.ccr.2013.05.003. Cancer Cell. 2013. PMID: 23764003 Free PMC article.
Melanoma and the tumor microenvironment.
Villanueva J, Herlyn M. Villanueva J, et al. Curr Oncol Rep. 2008 Sep;10(5):439-46. doi: 10.1007/s11912-008-0067-y. Curr Oncol Rep. 2008. PMID: 18706274 Free PMC article. Review.
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K.
Villanueva J, Vultur A, Lee JT, Somasundaram R, Fukunaga-Kalabis M, Cipolla AK, Wubbenhorst B, Xu X, Gimotty PA, Kee D, Santiago-Walker AE, Letrero R, D'Andrea K, Pushparajan A, Hayden JE, Brown KD, Laquerre S, McArthur GA, Sosman JA, Nathanson KL, Herlyn M. Villanueva J, et al. Cancer Cell. 2010 Dec 14;18(6):683-95. doi: 10.1016/j.ccr.2010.11.023. Cancer Cell. 2010. PMID: 21156289 Free PMC article.
Will engineered T cells expressing CD20 scFv eradicate Melanoma?
Somasundaram R, Villanueva J, Herlyn M. Somasundaram R, et al. Among authors: villanueva j. Mol Ther. 2011 Apr;19(4):638-40. doi: 10.1038/mt.2011.46. Mol Ther. 2011. PMID: 21455210 Free PMC article. No abstract available.
Sorting through the many opportunities for melanoma therapy.
Herlyn M, Villanueva J. Herlyn M, et al. Among authors: villanueva j. Pigment Cell Melanoma Res. 2011 Oct;24(5):975-7. doi: 10.1111/j.1755-148X.2011.00906.x. Pigment Cell Melanoma Res. 2011. PMID: 21899726 No abstract available.
Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s.
Chae YC, Caino MC, Lisanti S, Ghosh JC, Dohi T, Danial NN, Villanueva J, Ferrero S, Vaira V, Santambrogio L, Bosari S, Languino LR, Herlyn M, Altieri DC. Chae YC, et al. Among authors: villanueva j. Cancer Cell. 2012 Sep 11;22(3):331-44. doi: 10.1016/j.ccr.2012.07.015. Cancer Cell. 2012. PMID: 22975376 Free PMC article.
786 results