Villar HO - Search Results

1

Molecular determinants of non-specific recognition of delta, mu, and kappa opioid receptors.

Filizola M, Villar HO, Loew GH. Filizola M, et al. Among authors: villar ho. Bioorg Med Chem. 2001 Jan;9(1):69-76. doi: 10.1016/s0968-0896(00)00223-6. Bioorg Med Chem. 2001. PMID: 11197347

2

Toward the design of chemical libraries for mass screening biased against mutagenic compounds.

Llorens O, Perez JJ, Villar HO. Llorens O, et al. Among authors: villar ho. J Med Chem. 2001 Aug 16;44(17):2793-804. doi: 10.1021/jm0004594. J Med Chem. 2001. PMID: 11495590

3

LASSOO: a generalized directed diversity approach to the design and enrichment of chemical libraries.

Koehler RT, Dixon SL, Villar HO. Koehler RT, et al. Among authors: villar ho. J Med Chem. 1999 Nov 4;42(22):4695-704. doi: 10.1021/jm990312g. J Med Chem. 1999. PMID: 10579831

4

Ring systems in mutagenicity databases.

Kho R, Hodges JA, Hansen MR, Villar HO. Kho R, et al. Among authors: villar ho. J Med Chem. 2005 Oct 20;48(21):6671-8. doi: 10.1021/jm050564j. J Med Chem. 2005. PMID: 16220983

5

Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.

Hsu N, Cai D, Damodaran K, Gomez RF, Keck JG, Laborde E, Lum RT, Macke TJ, Martin G, Schow SR, Simon RJ, Villar HO, Wick MM, Beroza P. Hsu N, et al. Among authors: villar ho. J Med Chem. 2004 Sep 23;47(20):4875-80. doi: 10.1021/jm049950b. J Med Chem. 2004. PMID: 15369391

6

Characterization of the bioactive form and molecular determinants of recognition of cyclic enkephalin peptides at the delta-opioid receptor.

Chew C, Villar HO, Loew GH. Chew C, et al. Among authors: villar ho. Biopolymers. 1993 Apr;33(4):647-57. doi: 10.1002/bip.360330414. Biopolymers. 1993. PMID: 8385507

7

Molecular mechanism of delta-selectivity of indole analogs of nonpeptide opioids.

Maguire PA, Perez JJ, Tsai NF, Rodriguez L, Beatty MF, Villar HO, Kamal JJ, Upton C, Casy AF, Loew GH. Maguire PA, et al. Among authors: villar ho. Mol Pharmacol. 1993 Dec;44(6):1246-51. Mol Pharmacol. 1993. PMID: 8264562

8

Molecular electrostatic potential of D1 and D2 dopamine agonists.

Alkorta I, Villar HO. Alkorta I, et al. Among authors: villar ho. J Med Chem. 1994 Jan 7;37(1):210-3. doi: 10.1021/jm00027a028. J Med Chem. 1994. PMID: 7904647

9

Differentiation of delta, mu, and kappa opioid receptor agonists based on pharmacophore development and computed physicochemical properties.

Filizola M, Villar HO, Loew GH. Filizola M, et al. Among authors: villar ho. J Comput Aided Mol Des. 2001 Apr;15(4):297-307. doi: 10.1023/a:1011187320095. J Comput Aided Mol Des. 2001. PMID: 11349813

10

Molecular models for recognition and activation at the benzodiazepine receptor: a review.

Villar HO, Davies MF, Loew GH, Maguire PA. Villar HO, et al. Life Sci. 1991;48(7):593-602. doi: 10.1016/0024-3205(91)90533-h. Life Sci. 1991. PMID: 1671294 Review.

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