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EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells.
Andersen P, Pedersen MW, Woetmann A, Villingshøj M, Stockhausen MT, Odum N, Poulsen HS. Andersen P, et al. Among authors: villingshoj m. Int J Cancer. 2008 Jan 15;122(2):342-9. doi: 10.1002/ijc.23109. Int J Cancer. 2008. PMID: 17918184 Free article.
Improved response by co-targeting EGFR/EGFRvIII and Src family kinases in human cancer cells.
Andersen P, Villingshøj M, Poulsen HS, Stockhausen MT. Andersen P, et al. Among authors: villingshoj m. Cancer Invest. 2009 Feb;27(2):178-83. doi: 10.1080/07357900802570759. Cancer Invest. 2009. PMID: 19235590
Lack of the type III epidermal growth factor receptor mutation in colorectal cancer.
Spindler KL, Olsen DA, Nielsen JN, Brandslund I, Poulsen HS, Villingshøj M, Jakobsen A. Spindler KL, et al. Among authors: villingshoj m. Anticancer Res. 2006 Nov-Dec;26(6C):4889-93. Anticancer Res. 2006. PMID: 17214357
Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures.
Kristoffersen K, Villingshøj M, Poulsen HS, Stockhausen MT. Kristoffersen K, et al. Among authors: villingshoj m. Cancer Biol Ther. 2013 Jul;14(7):625-37. doi: 10.4161/cbt.24595. Epub 2013 May 10. Cancer Biol Ther. 2013. PMID: 23792644 Free PMC article.
Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature.
Kristoffersen K, Nedergaard MK, Villingshøj M, Borup R, Broholm H, Kjær A, Poulsen HS, Stockhausen MT. Kristoffersen K, et al. Among authors: villingshoj m. Cancer Biol Ther. 2014 Jul;15(7):862-77. doi: 10.4161/cbt.28876. Epub 2014 Apr 22. Cancer Biol Ther. 2014. PMID: 24755988 Free PMC article.
Maintenance of EGFR and EGFRvIII expressions in an in vivo and in vitro model of human glioblastoma multiforme.
Stockhausen MT, Broholm H, Villingshøj M, Kirchhoff M, Gerdes T, Kristoffersen K, Kosteljanetz M, Spang-Thomsen M, Poulsen HS. Stockhausen MT, et al. Among authors: villingshoj m. Exp Cell Res. 2011 Jul 1;317(11):1513-26. doi: 10.1016/j.yexcr.2011.04.001. Epub 2011 Apr 15. Exp Cell Res. 2011. PMID: 21514294
Analysis of the epidermal growth factor receptor specific transcriptome: effect of receptor expression level and an activating mutation.
Pedersen MW, Pedersen N, Damstrup L, Villingshøj M, Sønder SU, Rieneck K, Bovin LF, Spang-Thomsen M, Poulsen HS. Pedersen MW, et al. Among authors: villingshoj m. J Cell Biochem. 2005 Oct 1;96(2):412-27. doi: 10.1002/jcb.20554. J Cell Biochem. 2005. PMID: 16075456
VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance.
Michaelsen SR, Staberg M, Pedersen H, Jensen KE, Majewski W, Broholm H, Nedergaard MK, Meulengracht C, Urup T, Villingshøj M, Lukacova S, Skjøth-Rasmussen J, Brennum J, Kjær A, Lassen U, Stockhausen MT, Poulsen HS, Hamerlik P. Michaelsen SR, et al. Among authors: villingshoj m. Neuro Oncol. 2018 Oct 9;20(11):1462-1474. doi: 10.1093/neuonc/noy103. Neuro Oncol. 2018. PMID: 29939339 Free PMC article.
Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro.
Staberg M, Michaelsen SR, Olsen LS, Nedergaard MK, Villingshøj M, Stockhausen MT, Hamerlik P, Poulsen HS. Staberg M, et al. Among authors: villingshoj m. Cancer Cell Int. 2016 Apr 26;16:34. doi: 10.1186/s12935-016-0309-2. eCollection 2016. Cancer Cell Int. 2016. PMID: 27118928 Free PMC article.
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