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13 results
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Level of Notch activation determines the effect on growth and stem cell-like features in glioblastoma multiforme neurosphere cultures.
Kristoffersen K, Villingshøj M, Poulsen HS, Stockhausen MT. Kristoffersen K, et al. Among authors: villingshoj m. Cancer Biol Ther. 2013 Jul;14(7):625-37. doi: 10.4161/cbt.24595. Epub 2013 May 10. Cancer Biol Ther. 2013. PMID: 23792644 Free PMC article.
EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells.
Andersen P, Pedersen MW, Woetmann A, Villingshøj M, Stockhausen MT, Odum N, Poulsen HS. Andersen P, et al. Among authors: villingshoj m. Int J Cancer. 2008 Jan 15;122(2):342-9. doi: 10.1002/ijc.23109. Int J Cancer. 2008. PMID: 17918184 Free article.
VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance.
Michaelsen SR, Staberg M, Pedersen H, Jensen KE, Majewski W, Broholm H, Nedergaard MK, Meulengracht C, Urup T, Villingshøj M, Lukacova S, Skjøth-Rasmussen J, Brennum J, Kjær A, Lassen U, Stockhausen MT, Poulsen HS, Hamerlik P. Michaelsen SR, et al. Among authors: villingshoj m. Neuro Oncol. 2018 Oct 9;20(11):1462-1474. doi: 10.1093/neuonc/noy103. Neuro Oncol. 2018. PMID: 29939339 Free PMC article.
Targeting glioma stem-like cell survival and chemoresistance through inhibition of lysine-specific histone demethylase KDM2B.
Staberg M, Rasmussen RD, Michaelsen SR, Pedersen H, Jensen KE, Villingshøj M, Skjoth-Rasmussen J, Brennum J, Vitting-Seerup K, Poulsen HS, Hamerlik P. Staberg M, et al. Among authors: villingshoj m. Mol Oncol. 2018 Mar;12(3):406-420. doi: 10.1002/1878-0261.12174. Epub 2018 Feb 12. Mol Oncol. 2018. PMID: 29360266 Free PMC article.
Inhibition of histone deacetylases sensitizes glioblastoma cells to lomustine.
Staberg M, Michaelsen SR, Rasmussen RD, Villingshøj M, Poulsen HS, Hamerlik P. Staberg M, et al. Among authors: villingshoj m. Cell Oncol (Dordr). 2017 Feb;40(1):21-32. doi: 10.1007/s13402-016-0301-9. Epub 2016 Oct 20. Cell Oncol (Dordr). 2017. PMID: 27766591
Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro.
Staberg M, Michaelsen SR, Olsen LS, Nedergaard MK, Villingshøj M, Stockhausen MT, Hamerlik P, Poulsen HS. Staberg M, et al. Among authors: villingshoj m. Cancer Cell Int. 2016 Apr 26;16:34. doi: 10.1186/s12935-016-0309-2. eCollection 2016. Cancer Cell Int. 2016. PMID: 27118928 Free PMC article.
The impact of bevacizumab treatment on survival and quality of life in newly diagnosed glioblastoma patients.
Poulsen HS, Urup T, Michaelsen SR, Staberg M, Villingshøj M, Lassen U. Poulsen HS, et al. Among authors: villingshoj m. Cancer Manag Res. 2014 Sep 26;6:373-87. doi: 10.2147/CMAR.S39306. eCollection 2014. Cancer Manag Res. 2014. PMID: 25298738 Free PMC article. Review.
Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature.
Kristoffersen K, Nedergaard MK, Villingshøj M, Borup R, Broholm H, Kjær A, Poulsen HS, Stockhausen MT. Kristoffersen K, et al. Among authors: villingshoj m. Cancer Biol Ther. 2014 Jul;15(7):862-77. doi: 10.4161/cbt.28876. Epub 2014 Apr 22. Cancer Biol Ther. 2014. PMID: 24755988 Free PMC article.
Maintenance of EGFR and EGFRvIII expressions in an in vivo and in vitro model of human glioblastoma multiforme.
Stockhausen MT, Broholm H, Villingshøj M, Kirchhoff M, Gerdes T, Kristoffersen K, Kosteljanetz M, Spang-Thomsen M, Poulsen HS. Stockhausen MT, et al. Among authors: villingshoj m. Exp Cell Res. 2011 Jul 1;317(11):1513-26. doi: 10.1016/j.yexcr.2011.04.001. Epub 2011 Apr 15. Exp Cell Res. 2011. PMID: 21514294
Improved response by co-targeting EGFR/EGFRvIII and Src family kinases in human cancer cells.
Andersen P, Villingshøj M, Poulsen HS, Stockhausen MT. Andersen P, et al. Among authors: villingshoj m. Cancer Invest. 2009 Feb;27(2):178-83. doi: 10.1080/07357900802570759. Cancer Invest. 2009. PMID: 19235590
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