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Molecular mechanism of complement inhibition by the trypanosome receptor ISG65.
Cook AD, Carrington M, Higgins MK. Cook AD, et al. Elife. 2024 Apr 24;12:RP88960. doi: 10.7554/eLife.88960. Elife. 2024. PMID: 38655765
African trypanosomes replicate within infected mammals where they are exposed to the complement system. This system centres around complement C3, which is present in a soluble form in serum but becomes covalently deposited onto the surfaces of pathogens after proteolytic c …
African trypanosomes replicate within infected mammals where they are exposed to the complement system. This system centres around complemen …
Evaluation of power wheelchair driving performance in simulator compared to driving in real-life situations: the SIMADAPT (simulator ADAPT) project-a pilot study.
Fraudet B, Leblong E, Piette P, Nicolas B, Gouranton V, Babel M, Devigne L, Pasteau F, Gallien P. Fraudet B, et al. J Neuroeng Rehabil. 2024 Apr 23;21(1):60. doi: 10.1186/s12984-024-01354-5. J Neuroeng Rehabil. 2024. PMID: 38654367
METHODS: Three driving circuits of progressive difficulty levels (C1, C2, C3) that were elaborated to assess the driving performances with PWC in indoor situations, were used in this study. ...The driving performances between VR and R conditions were statistically differen …
METHODS: Three driving circuits of progressive difficulty levels (C1, C2, C3) that were elaborated to assess the driving performances …
Sinomenine Hydrochloride Protects IgA Nephropathy Through Regulating Cell Growth and Apoptosis of T and B Lymphocytes.
Li JJ, Li L, Li S, Tang XY, Sun HF, Liu JX. Li JJ, et al. Drug Des Devel Ther. 2024 Apr 17;18:1247-1262. doi: 10.2147/DDDT.S449119. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 38645988 Free PMC article.
After extracting T and B cells using immunomagnetic beads, we assessed their purity, cell cycle phase, and apoptosis stage through flow cytometry. ...Furthermore, SH arrested the cell cycle of lymphocytes T and B from the spleen of IgAN rats. Regarding the mechanism …
After extracting T and B cells using immunomagnetic beads, we assessed their purity, cell cycle phase, and apoptosis stage through fl …
Bioaccumulation of Perfluoroalkyl Sulfonamides (FASA).
Pickard HM, Haque F, Sunderland EM. Pickard HM, et al. Environ Sci Technol Lett. 2024 Apr 9;11(4):350-356. doi: 10.1021/acs.estlett.4c00143. Epub 2024 Mar 14. Environ Sci Technol Lett. 2024. PMID: 38645703 Free PMC article.
FASA are precursors to terminal per- and polyfluoroalkyl substances (PFAS) that are abundant in diverse consumer products and aqueous film-forming foams manufactured using electrochemical fluorination (ECF AFFF). In this study, FASA with C3-C8 carbon chain lengths were det …
FASA are precursors to terminal per- and polyfluoroalkyl substances (PFAS) that are abundant in diverse consumer products and aqueous film-f …
Oxidation of Molybdenum-Based Single-Metallic/bimetallic Carbide MXenes in Aqueous Suspensions: Mechanistic Insights.
Hussain N, Chae A, Iqbal A, Doo S, Naqvi SM, Hassan T, Lee AS, Oh T, Koo CM. Hussain N, et al. Langmuir. 2024 Apr 21. doi: 10.1021/acs.langmuir.4c00568. Online ahead of print. Langmuir. 2024. PMID: 38644569
Therefore, the oxidation mechanisms of Mo-based single-metallic/bimetallic carbide MXenes including Mo(2)CT(x), Mo(2)TiC(2)T(x), and Mo(2)Ti(2)C(3)T(x) in aqueous suspensions were investigated for the first time in this study. ...Notably, the Mo(2)CT(x) MXene deviat …
Therefore, the oxidation mechanisms of Mo-based single-metallic/bimetallic carbide MXenes including Mo(2)CT(x), Mo(2)TiC(2)T(x), and …
Zhen-Wu-Tang ameliorates lupus nephritis by diminishing renal tissue-resident memory CD8(+) T cells via suppressing IL-15/STAT3 pathway.
Liang CL, Wei YY, Chen Y, Luo Y, Qin F, Chen Y, Liu H, Qiu F, Wu J, Yang B, Liu Y, Dai Z. Liang CL, et al. Biomed Pharmacother. 2024 Apr 20;174:116597. doi: 10.1016/j.biopha.2024.116597. Online ahead of print. Biomed Pharmacother. 2024. PMID: 38643544
Here we aimed to define the immunological mechanisms underlying the effects of ZWT on LN and to determine whether it affects renal tissue-resident memory T (T(RM)) cells. Murine LN was induced by a single injection of pristane, while in vitro T(RM) cells diff …
Here we aimed to define the immunological mechanisms underlying the effects of ZWT on LN and to determine whether it affects renal tissue-re …
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Diseases and Injuries Collaborators. GBD 2021 Diseases and Injuries Collaborators. Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print. Lancet. 2024. PMID: 38642570
Comparative Anatomic Analysis of Neuronavigated Transmastoid-Infralabyrinthine Approaches for Jugular Fossa Pathologies: Short Anterior Rerouting Versus Nonrerouting and Tailored Nonrerouting Techniques.
Cinibulak Z, Martinez Santos JL, Poggenborg J, Schliwa S, Ostovar N, Keles A, Baskaya MK, Nakamura M. Cinibulak Z, et al. Oper Neurosurg (Hagerstown). 2024 Apr 18. doi: 10.1227/ons.0000000000001158. Online ahead of print. Oper Neurosurg (Hagerstown). 2024. PMID: 38634695
However, adding some tailored steps to the NR-T permitted comparable access to the JF. CONCLUSION: Neuronavigated TI-A with the short-rerouting technique permits wider access to the JF compared with the NR-T. However, the tailored NR-T provides comparable acc …
However, adding some tailored steps to the NR-T permitted comparable access to the JF. CONCLUSION: Neuronavigated TI-A with the short …
Boosting the immunogenicity of the CoronaVac SARS-CoV-2 inactivated vaccine with Huoxiang Suling Shuanghua Decoction: a randomized, double-blind, placebo-controlled study.
Tang R, Wang L, Zhang J, Fei W, Zhang R, Liu J, Lv M, Wang M, Lv R, Nan H, Tao R, Chen Y, Chen Y, Jiang Y, Zhang H. Tang R, et al. Front Immunol. 2024 Apr 3;15:1298471. doi: 10.3389/fimmu.2024.1298471. eCollection 2024. Front Immunol. 2024. PMID: 38633263 Free PMC article. Clinical Trial.
Safety aspects were assessed by recording local and systemic adverse events, and by blood and urine biochemistry and liver and kidney function tests. Main outcomes evaluated included serum anti-RBD IgG titer, T lymphocyte subsets, serum IgG and IgM levels, complement compo …
Safety aspects were assessed by recording local and systemic adverse events, and by blood and urine biochemistry and liver and kidney functi …
[Effectiveness analysis of revision surgery after total hip arthroplasty assisted by artificial intelligence preoperative planning system].
Zhu J, Sun J, Liu J, Ma B, Zhang C, Zhang C, Xia T, Shen J. Zhu J, et al. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2024 Apr 15;38(4):455-460. doi: 10.7507/1002-1892.202312099. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2024. PMID: 38632066 Free PMC article. Chinese.
The range of motion of hip joint was (111.0910.11) at 6 months after operation, which was significantly different from (79.1318.50) before operation ( t=-7.269, P<0.001). CONCLUSION: AIHIP system can improve the accuracy of revision surgery, reduce the difficulty of sur …
The range of motion of hip joint was (111.0910.11) at 6 months after operation, which was significantly different from (79.1318.50) before o …
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