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XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.
Lawlor KE, Feltham R, Yabal M, Conos SA, Chen KW, Ziehe S, Graß C, Zhan Y, Nguyen TA, Hall C, Vince AJ, Chatfield SM, D'Silva DB, Pang KC, Schroder K, Silke J, Vaux DL, Jost PJ, Vince JE. Lawlor KE, et al. Among authors: vince je, vince aj. Cell Rep. 2017 Jul 18;20(3):668-682. doi: 10.1016/j.celrep.2017.06.073. Cell Rep. 2017. PMID: 28723569 Free article.
TWEAK shall inherit the earth.
Vince JE, Silke J. Vince JE, et al. Cell Death Differ. 2006 Nov;13(11):1842-4. doi: 10.1038/sj.cdd.4402027. Epub 2006 Aug 25. Cell Death Differ. 2006. PMID: 16932755 No abstract available.
Cytoplasmic p53 is not required for PUMA-induced apoptosis.
Callus BA, Ekert PG, Heraud JE, Jabbour AM, Kotevski A, Vince JE, Silke J, Vaux DL. Callus BA, et al. Among authors: vince je. Cell Death Differ. 2008 Jan;15(1):213-5; author reply 215-6. doi: 10.1038/sj.cdd.4402245. Epub 2007 Nov 9. Cell Death Differ. 2008. PMID: 17992194 No abstract available.
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.
Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, Benetatos CA, Chunduru SK, Condon SM, McKinlay M, Brink R, Leverkus M, Tergaonkar V, Schneider P, Callus BA, Koentgen F, Vaux DL, Silke J. Vince JE, et al. Cell. 2007 Nov 16;131(4):682-93. doi: 10.1016/j.cell.2007.10.037. Cell. 2007. PMID: 18022363 Free article.
CARP2 deficiency does not alter induction of NF-kappaB by TNFalpha.
Ahmed AU, Moulin M, Coumailleau F, Wong WW, Miasari M, Carter H, Silke J, Cohen-Tannoudji M, Vince JE, Vaux DL. Ahmed AU, et al. Among authors: vince je. Curr Biol. 2009 Jan 13;19(1):R15-7; author reply R17-9. doi: 10.1016/j.cub.2008.11.040. Curr Biol. 2009. PMID: 19138581 Free article. No abstract available.
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.
Vince JE, Pantaki D, Feltham R, Mace PD, Cordier SM, Schmukle AC, Davidson AJ, Callus BA, Wong WW, Gentle IE, Carter H, Lee EF, Walczak H, Day CL, Vaux DL, Silke J. Vince JE, et al. J Biol Chem. 2009 Dec 18;284(51):35906-15. doi: 10.1074/jbc.M109.072256. J Biol Chem. 2009. PMID: 19815541 Free PMC article.
Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.
Feltham R, Moulin M, Vince JE, Mace PD, Wong WW, Anderton H, Day CL, Vaux DL, Silke J. Feltham R, et al. Among authors: vince je. J Biol Chem. 2010 Jun 4;285(23):17525-36. doi: 10.1074/jbc.M109.087635. Epub 2010 Mar 30. J Biol Chem. 2010. PMID: 20356846 Free PMC article.
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