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The ability of an attaching and effacing pathogen to trigger localized actin assembly contributes to virulence by promoting mucosal attachment.
Mallick EM, Garber JJ, Vanguri VK, Balasubramanian S, Blood T, Clark S, Vingadassalom D, Louissaint C, McCormick B, Snapper SB, Leong JM. Mallick EM, et al. Among authors: vingadassalom d. Cell Microbiol. 2014 Sep;16(9):1405-24. doi: 10.1111/cmi.12302. Epub 2014 Jun 2. Cell Microbiol. 2014. PMID: 24780054 Free PMC article.
Structural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli.
de Groot JC, Schlüter K, Carius Y, Quedenau C, Vingadassalom D, Faix J, Weiss SM, Reichelt J, Standfuss-Gabisch C, Lesser CF, Leong JM, Heinz DW, Büssow K, Stradal TE. de Groot JC, et al. Among authors: vingadassalom d. Structure. 2011 Sep 7;19(9):1294-306. doi: 10.1016/j.str.2011.06.015. Structure. 2011. PMID: 21893288 Free PMC article.
A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis.
O'Brien-Simpson NM, Holden JA, Lenzo JC, Tan Y, Brammar GC, Walsh KA, Singleton W, Orth RKH, Slakeski N, Cross KJ, Darby IB, Becher D, Rowe T, Morelli AB, Hammet A, Nash A, Brown A, Ma B, Vingadassalom D, McCluskey J, Kleanthous H, Reynolds EC. O'Brien-Simpson NM, et al. Among authors: vingadassalom d. NPJ Vaccines. 2016 Dec 1;1:16022. doi: 10.1038/npjvaccines.2016.22. eCollection 2016. NPJ Vaccines. 2016. PMID: 29263860 Free PMC article.
An unusual primary sigma factor in the Bacteroidetes phylum.
Vingadassalom D, Kolb A, Mayer C, Rybkine T, Collatz E, Podglajen I. Vingadassalom D, et al. Mol Microbiol. 2005 May;56(4):888-902. doi: 10.1111/j.1365-2958.2005.04590.x. Mol Microbiol. 2005. PMID: 15853878 Free article.