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Calcium signaling in neurodegeneration.
Marambaud P, Dreses-Werringloer U, Vingtdeux V. Marambaud P, et al. Mol Neurodegener. 2009 May 6;4:20. doi: 10.1186/1750-1326-4-20. Mol Neurodegener. 2009. PMID: 19419557 Free PMC article.
CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice.
Vingtdeux V, Chang EH, Frattini SA, Zhao H, Chandakkar P, Adrien L, Strohl JJ, Gibson EL, Ohmoto M, Matsumoto I, Huerta PT, Marambaud P. Vingtdeux V, et al. Sci Rep. 2016 Apr 12;6:24250. doi: 10.1038/srep24250. Sci Rep. 2016. PMID: 27066908 Free PMC article.
CALHM1 controls the Ca²⁺-dependent MEK, ERK, RSK and MSK signaling cascade in neurons.
Dreses-Werringloer U, Vingtdeux V, Zhao H, Chandakkar P, Davies P, Marambaud P. Dreses-Werringloer U, et al. J Cell Sci. 2013 Mar 1;126(Pt 5):1199-206. doi: 10.1242/jcs.117135. Epub 2013 Jan 23. J Cell Sci. 2013. PMID: 23345406 Free PMC article.
CALHM1 ion channel elicits amyloid-β clearance by insulin-degrading enzyme in cell lines and in vivo in the mouse brain.
Vingtdeux V, Chandakkar P, Zhao H, Blanc L, Ruiz S, Marambaud P. Vingtdeux V, et al. J Cell Sci. 2015 Jul 1;128(13):2330-8. doi: 10.1242/jcs.167270. Epub 2015 May 21. J Cell Sci. 2015. PMID: 25999473 Free PMC article.
Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β.
Ma T, Chen Y, Vingtdeux V, Zhao H, Viollet B, Marambaud P, Klann E. Ma T, et al. J Neurosci. 2014 Sep 3;34(36):12230-8. doi: 10.1523/JNEUROSCI.1694-14.2014. J Neurosci. 2014. PMID: 25186765 Free PMC article.
Identification and biology of α-secretase.
Vingtdeux V, Marambaud P. Vingtdeux V, et al. J Neurochem. 2012 Jan;120 Suppl 1:34-45. doi: 10.1111/j.1471-4159.2011.07477.x. Epub 2011 Nov 28. J Neurochem. 2012. PMID: 22121879 Review.
Resveratrol mitigates lipopolysaccharide- and Aβ-mediated microglial inflammation by inhibiting the TLR4/NF-κB/STAT signaling cascade.
Capiralla H, Vingtdeux V, Zhao H, Sankowski R, Al-Abed Y, Davies P, Marambaud P. Capiralla H, et al. J Neurochem. 2012 Feb;120(3):461-72. doi: 10.1111/j.1471-4159.2011.07594.x. Epub 2011 Dec 16. J Neurochem. 2012. PMID: 22118570 Free PMC article.
CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzheimer's disease.
Koppel J, Campagne F, Vingtdeux V, Dreses-Werringloer U, Ewers M, Rujescu D, Hampel H, Gordon ML, Christen E, Chapuis J, Greenwald BS, Davies P, Marambaud P. Koppel J, et al. Mol Med. 2011 Sep-Oct;17(9-10):974-9. doi: 10.2119/molmed.2011.00154. Epub 2011 May 24. Mol Med. 2011. PMID: 21629967 Free PMC article.
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor protein.
Chapuis J, Vingtdeux V, Campagne F, Davies P, Marambaud P. Chapuis J, et al. Hum Mol Genet. 2011 May 15;20(10):2026-36. doi: 10.1093/hmg/ddr085. Epub 2011 Feb 28. Hum Mol Genet. 2011. PMID: 21357679 Free PMC article.
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