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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1978 2
1979 5
1980 9
1981 7
1982 12
1983 5
1984 12
1985 17
1986 16
1987 21
1988 14
1989 22
1990 28
1991 19
1992 19
1993 11
1994 11
1995 11
1996 13
1997 11
1998 22
1999 16
2000 20
2001 19
2002 23
2003 24
2004 20
2005 16
2006 27
2007 31
2008 23
2009 27
2010 26
2011 28
2012 21
2013 16
2014 25
2015 24
2016 25
2017 32
2018 32
2019 30
2020 35
2021 22
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787 results
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Page 1
An update on vinpocetine: New discoveries and clinical implications.
Zhang YS, Li JD, Yan C. Zhang YS, et al. Eur J Pharmacol. 2018 Jan 15;819:30-34. doi: 10.1016/j.ejphar.2017.11.041. Epub 2017 Nov 26. Eur J Pharmacol. 2018. PMID: 29183836 Free PMC article. Review.
Currently, vinpocetine is also available in the market as a dietary supplement to enhance cognition and memory. ...These novel findings may facilitate the repositioning of vinpocetine for preventing or treating relevant disorders in humans....
Currently, vinpocetine is also available in the market as a dietary supplement to enhance cognition and memory. ...These novel findin …
Vinpocetine protects against the development of experimental abdominal aortic aneurysms.
Zhang C, Hsu CG, Mohan A, Shi H, Li D, Yan C. Zhang C, et al. Clin Sci (Lond). 2020 Nov 27;134(22):2959-2976. doi: 10.1042/CS20201057. Clin Sci (Lond). 2020. PMID: 33111936
We showed that vinpocetine pre-treatment remarkably attenuated aneurysmal dilation assessed by diameter and volume. ...Taken together, our findings reveal a novel role of vinpocetine in AAA formation, development and progression. Given the excellent safety profile o …
We showed that vinpocetine pre-treatment remarkably attenuated aneurysmal dilation assessed by diameter and volume. ...Taken together …
Vinpocetine in the treatment of poststroke cognitive dysfunction: A protocol for systematic review and meta-analysis.
Liu Y, Yin Y, Lu QL, Dan Y, Xu MS, Song G, Li C. Liu Y, et al. Medicine (Baltimore). 2019 Feb;98(6):e13685. doi: 10.1097/MD.0000000000013685. Medicine (Baltimore). 2019. PMID: 30732122 Free PMC article. Review.
BACKGROUND: Previous clinical trials have reported that vinpocetine can be used for the treatment of cognitive dysfunction. ...All randomized controlled trials (RCTs) of vinpocetine for PSCD will be considered for inclusion without the language restrictions. ...
BACKGROUND: Previous clinical trials have reported that vinpocetine can be used for the treatment of cognitive dysfunction. ...All ra …
Vinpocetine. Monograph.
[No authors listed] [No authors listed] Altern Med Rev. 2002 Jun;7(3):240-3. Altern Med Rev. 2002. PMID: 12126465 Free article. Review. No abstract available.
Vinpocetine mitigates aluminum-induced cognitive impairment in socially isolated rats.
Ali AA, Ahmed HI, Khaleel SA, Abu-Elfotuh K. Ali AA, et al. Physiol Behav. 2019 Sep 1;208:112571. doi: 10.1016/j.physbeh.2019.112571. Epub 2019 Jun 6. Physiol Behav. 2019. PMID: 31175888
Several reports have highlighted the role of vinpocetine in Alzheimer's disease (AD). However, the role of vinpocetine in AD under social isolation conditions has not yet been elucidated. ...Hence, this study provides profound insights into the role of vin …
Several reports have highlighted the role of vinpocetine in Alzheimer's disease (AD). However, the role of vinpocetine …
Anti-inflammatory effects of vinpocetine in LPS-stimulated microglia via activation of AMPK.
Zhou Q, Guo D, Li X, Wang Y, Ye X, Xue S, Wang X. Zhou Q, et al. An Acad Bras Cienc. 2020 Nov 20;92(4):e20200241. doi: 10.1590/0001-3765202020200241. eCollection 2020. An Acad Bras Cienc. 2020. PMID: 33237143 Free article.
The present study investigated the anti-neuroinflammatory effects of vinpocetine induced by lipopolysaccharide (LPS) in BV2 microglia. BV2 microglia were pretreated with vinpocetine, and then stimulated with LPS (100 ng/mL). ...AMPK inhibition by siRNA blocked the a …
The present study investigated the anti-neuroinflammatory effects of vinpocetine induced by lipopolysaccharide (LPS) in BV2 microglia …
Vinpocetine for acute ischaemic stroke.
Bereczki D, Fekete I. Bereczki D, et al. Cochrane Database Syst Rev. 2008 Jan 23;2008(1):CD000480. doi: 10.1002/14651858.CD000480.pub2. Cochrane Database Syst Rev. 2008. PMID: 18253980 Free PMC article. Review.
BACKGROUND: Vasoactive and neuroprotective drugs such as vinpocetine are used to treat stroke in some countries. OBJECTIVES: To assess the effect of vinpocetine in acute ischaemic stroke. ...We contacted researchers in the field and four pharmaceutical companies tha …
BACKGROUND: Vasoactive and neuroprotective drugs such as vinpocetine are used to treat stroke in some countries. OBJECTIVES: To asses …
Vinpocetine Suppresses Streptococcus pneumoniae-Induced Inflammation via Inhibition of ERK1 by CYLD.
Komatsu K, Nam DH, Lee JY, Yoneda G, Yan C, Li JD. Komatsu K, et al. J Immunol. 2020 Feb 15;204(4):933-942. doi: 10.4049/jimmunol.1901299. Epub 2020 Jan 3. J Immunol. 2020. PMID: 31900337 Free article.
Interestingly, vinpocetine inhibited S. pneumoniae-induced inflammation via upregulating a key negative regulator cylindromatosis (CYLD). ...Importantly, the postinfection administration of vinpocetine markedly inhibited middle ear inflammation induced by …
Interestingly, vinpocetine inhibited S. pneumoniae-induced inflammation via upregulating a key negative regulator cylindromato …
Vinpocetine reduces cisplatin-induced acute kidney injury through inhibition of NF-kappaB pathway and activation of Nrf2/ARE pathway in rats.
Song W, Yin W, Ding L, Gao Y, Xu J, Yang Y, He X, Gong P, Wei L, Chen W, Zhang J. Song W, et al. Int Urol Nephrol. 2020 Jul;52(7):1389-1401. doi: 10.1007/s11255-020-02485-z. Epub 2020 May 16. Int Urol Nephrol. 2020. PMID: 32418008
In this study, we investigated the effects and mechanisms of vinpocetine in an animal model of cisplatin-induced acute renal injury. ...Therefore, vinpocetine is a promising therapeutic drug for the treatment of cisplatin-induced acute kidney injury....
In this study, we investigated the effects and mechanisms of vinpocetine in an animal model of cisplatin-induced acute renal injury. …
Synthesis and biological evaluation of Vinpocetine derivatives.
Pan BW, Shi Y, Li WC, Wang Q, Pan M, Wu Q, Fu HZ. Pan BW, et al. Bioorg Med Chem Lett. 2020 Jan 15;30(2):126472. doi: 10.1016/j.bmcl.2019.05.052. Epub 2019 May 28. Bioorg Med Chem Lett. 2020. PMID: 31859156
A new series of Vinpocetine derivatives were synthesized and evaluated for their inhibitory activity on PDE1A in vitro. ...After further screening, compounds 5, 7, 21, 34 and Vinpocetine were selected to examine the vasorelaxant effects on endothelium-intact rat tho …
A new series of Vinpocetine derivatives were synthesized and evaluated for their inhibitory activity on PDE1A in vitro. ...After furt …
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