Total synthesis and determination of the absolute configuration of rakicidin A.
Sang F, Li D, Sun X, Cao X, Wang L, Sun J, Sun B, Wu L, Yang G, Chu X, Wang J, Dong C, Geng Y, Jiang H, Long H, Chen S, Wang G, Zhang S, Zhang Q, Chen Y.
Sang F, et al.
J Am Chem Soc. 2014 Nov 5;136(44):15787-91. doi: 10.1021/ja509379j. Epub 2014 Oct 24.
J Am Chem Soc. 2014.
PMID: 25286338
This work suggests strategies for the determination of unknown chiral centers in other cyclic depsipeptides, such as rakicidin B, C, D, BE-43547, and vinylamycin, and facilitates the investigations of rakicidin A as an anticancer stem cell agent....
This work suggests strategies for the determination of unknown chiral centers in other cyclic depsipeptides, such as rakicidin B, C, D, BE-4 …