Viola KL - Search Results

1

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.

Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed R, Liosatos M, Morgan TE, Rozovsky I, Trommer B, Viola KL, Wals P, Zhang C, Finch CE, Krafft GA, Klein WL. Lambert MP, et al. Among authors: viola kl. Proc Natl Acad Sci U S A. 1998 May 26;95(11):6448-53. doi: 10.1073/pnas.95.11.6448. Proc Natl Acad Sci U S A. 1998. PMID: 9600986 Free PMC article.

2

Reversible inactivation of superoxide-sensitive aconitase in Abeta1-42-treated neuronal cell lines.

Longo VD, Viola KL, Klein WL, Finch CE. Longo VD, et al. Among authors: viola kl. J Neurochem. 2000 Nov;75(5):1977-85. doi: 10.1046/j.1471-4159.2000.0751977.x. J Neurochem. 2000. PMID: 11032887 Free article.

3

Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies.

Lambert MP, Viola KL, Chromy BA, Chang L, Morgan TE, Yu J, Venton DL, Krafft GA, Finch CE, Klein WL. Lambert MP, et al. Among authors: viola kl. J Neurochem. 2001 Nov;79(3):595-605. doi: 10.1046/j.1471-4159.2001.00592.x. J Neurochem. 2001. PMID: 11701763 Free article.

4

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

Wang HW, Pasternak JF, Kuo H, Ristic H, Lambert MP, Chromy B, Viola KL, Klein WL, Stine WB, Krafft GA, Trommer BL. Wang HW, et al. Among authors: viola kl. Brain Res. 2002 Jan 11;924(2):133-40. doi: 10.1016/s0006-8993(01)03058-x. Brain Res. 2002. PMID: 11750898

5

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss.

Gong Y, Chang L, Viola KL, Lacor PN, Lambert MP, Finch CE, Krafft GA, Klein WL. Gong Y, et al. Among authors: viola kl. Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10417-22. doi: 10.1073/pnas.1834302100. Epub 2003 Aug 18. Proc Natl Acad Sci U S A. 2003. PMID: 12925731 Free PMC article.

6

Self-assembly of Abeta(1-42) into globular neurotoxins.

Chromy BA, Nowak RJ, Lambert MP, Viola KL, Chang L, Velasco PT, Jones BW, Fernandez SJ, Lacor PN, Horowitz P, Finch CE, Krafft GA, Klein WL. Chromy BA, et al. Among authors: viola kl. Biochemistry. 2003 Nov 11;42(44):12749-60. doi: 10.1021/bi030029q. Biochemistry. 2003. PMID: 14596589

7

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL. Lacor PN, et al. Among authors: viola kl. J Neurosci. 2004 Nov 10;24(45):10191-200. doi: 10.1523/JNEUROSCI.3432-04.2004. J Neurosci. 2004. PMID: 15537891 Free PMC article.

8

Monoclonal antibodies that target pathological assemblies of Abeta.

Lambert MP, Velasco PT, Chang L, Viola KL, Fernandez S, Lacor PN, Khuon D, Gong Y, Bigio EH, Shaw P, De Felice FG, Krafft GA, Klein WL. Lambert MP, et al. Among authors: viola kl. J Neurochem. 2007 Jan;100(1):23-35. doi: 10.1111/j.1471-4159.2006.04157.x. Epub 2006 Nov 20. J Neurochem. 2007. PMID: 17116235 Free article.

9

Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease.

Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, Wood M, Viola KL, Klein WL. Lacor PN, et al. Among authors: viola kl. J Neurosci. 2007 Jan 24;27(4):796-807. doi: 10.1523/JNEUROSCI.3501-06.2007. J Neurosci. 2007. PMID: 17251419 Free PMC article.

10

Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine.

De Felice FG, Velasco PT, Lambert MP, Viola K, Fernandez SJ, Ferreira ST, Klein WL. De Felice FG, et al. J Biol Chem. 2007 Apr 13;282(15):11590-601. doi: 10.1074/jbc.M607483200. Epub 2007 Feb 16. J Biol Chem. 2007. PMID: 17308309 Free article.

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