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Intravenous immunoglobulin for repeated IVF failure and unexplained infertility.
Virro MR, Winger EE, Reed JL. Virro MR, et al. Am J Reprod Immunol. 2012 Sep;68(3):218-25. doi: 10.1111/j.1600-0897.2012.01169.x. Epub 2012 Jul 17. Am J Reprod Immunol. 2012. PMID: 22805355
Sperm chromatin structure assay (SCSA) parameters are related to fertilization, blastocyst development, and ongoing pregnancy in in vitro fertilization and intracytoplasmic sperm injection cycles.
Virro MR, Larson-Cook KL, Evenson DP. Virro MR, et al. Fertil Steril. 2004 May;81(5):1289-95. doi: 10.1016/j.fertnstert.2003.09.063. Fertil Steril. 2004. PMID: 15136092
Interference of gadolinium dechelated from MR contrast agents by calcium signaling in neuronal cells of GnRH.
Baykara M, Ozcan M, Bilgen M, Kelestimur H. Baykara M, et al. J Cell Physiol. 2020 Aug 1. doi: 10.1002/jcp.30000. Online ahead of print. J Cell Physiol. 2020. PMID: 32740939
The study used the mouse GT1-7 cell line as a model system, and Fura-2 based calcium imaging for detecting the interruption of intracellular calcium transport by the extracellular presence of Gd3+ as released from the CAs; gadodiamide and gadoterate meglumine, when the cells were …
The study used the mouse GT1-7 cell line as a model system, and Fura-2 based calcium imaging for detecting the interruption of intracellular …
Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model.
Yamamoto J, Miyake K, Han Q, Tan Y, Inubushi S, Sugisawa N, Higuchi T, Tashiro Y, Nishino H, Homma Y, Matsuyama R, Chawla SP, Bouvet M, Singh SR, Endo I, Hoffman RM. Yamamoto J, et al. Cancer Lett. 2020 Jul 30:S0304-3835(20)30390-6. doi: 10.1016/j.canlet.2020.07.034. Online ahead of print. Cancer Lett. 2020. PMID: 32739322
The effects of MR on TRAIL-R2 expression and sensitivity to tigatuzumab were evaluated in vitro. An orthotopic pancreatic cancer mouse model was established to evaluate the efficacy of MR using oral recombinant methioninase (o-rMETase), and the efficacy of ti …
The effects of MR on TRAIL-R2 expression and sensitivity to tigatuzumab were evaluated in vitro. An orthotopic pancreatic canc …
Beneficial Effects of Mineralocorticoid Receptor Antagonism on Myocardial Fibrosis in an Experimental Model of the Myxomatous Degeneration of the Mitral Valve.
Ibarrola J, Garaikoetxea M, Garcia-Peña A, Matilla L, Jover E, Bonnard B, Cuesta M, Fernández-Celis A, Jaisser F, López-Andrés N. Ibarrola J, et al. Int J Mol Sci. 2020 Jul 28;21(15):E5372. doi: 10.3390/ijms21155372. Int J Mol Sci. 2020. PMID: 32731636
The following effects are blocked by MRA: in vitro, in adult human cardiac fibroblasts, NDF-treatment-induced myofibroblast activation, collagen type I and proteoglycans secretion. Our findings demonstrate, for the first time, the contribution of the mineralocorticoid rece …
The following effects are blocked by MRA: in vitro, in adult human cardiac fibroblasts, NDF-treatment-induced myofibroblast activatio …
GNS561 acts as a potent anti-fibrotic and pro-fibrolytic agent in liver fibrosis through TGF-β1 inhibition.
Bestion E, Jilkova ZM, Mège JL, Novello M, Kurma K, Pour STA, Lalmanach G, Vanderlynden L, Fizanne L, Bassissi F, Rachid M, Tracz J, Boursier J, Courcambeck J, Serdjebi C, Ansaldi C, Decaens T, Halfon P, Brun S. Bestion E, et al. Ther Adv Chronic Dis. 2020 Jul 16;11:2040622320942042. doi: 10.1177/2040622320942042. eCollection 2020. Ther Adv Chronic Dis. 2020. PMID: 32728410 Free PMC article.
METHODS: The anti-fibrotic effect of GNS561 was determined in vitro using LX-2 hepatic stellate cells (HSCs) and primary human HSCs by studying cell viability, activity of caspases 3/7, autophagic flux, cathepsin maturation and activity, HSC activation and transforming gro …
METHODS: The anti-fibrotic effect of GNS561 was determined in vitro using LX-2 hepatic stellate cells (HSCs) and primary human HSCs b …
In vivo quantitative mapping of human mitochondrial cardiac membrane potential: a feasibility study.
Pelletier-Galarneau M, Petibon Y, Ma C, Han P, Kim SJW, Detmer FJ, Yokell D, Guehl N, Normandin M, El Fakhri G, Alpert NM. Pelletier-Galarneau M, et al. Eur J Nucl Med Mol Imaging. 2020 Jul 27. doi: 10.1007/s00259-020-04878-9. Online ahead of print. Eur J Nucl Med Mol Imaging. 2020. PMID: 32719915
The extracellular space fraction (f(ECS)) was simultaneously measured using MR T1-mapping images acquired at baseline and 15 min after gadolinium injection with correction for the subject's hematocrit level. ...RESULTS: In 13 healthy subjects, average tissue membrane poten …
The extracellular space fraction (f(ECS)) was simultaneously measured using MR T1-mapping images acquired at baseline and 15 min afte …
Gd(DOTA)-grafted submicronic polysaccharide-based particles functionalized with fucoidan as potential MR contrast agent able to target human activated platelets.
Forero Ramirez LM, Gobin E, Aid-Launais R, Journe C, Moraes FC, Picton L, Le Cerf D, Letourneur D, Chauvierre C, Chaubet F. Forero Ramirez LM, et al. Carbohydr Polym. 2020 Oct 1;245:116457. doi: 10.1016/j.carbpol.2020.116457. Epub 2020 May 25. Carbohydr Polym. 2020. PMID: 32718599
Their capacity to bind to human activated platelets was evidenced in vitro as well as their cytocompatibility with human endothelial cells. ...
Their capacity to bind to human activated platelets was evidenced in vitro as well as their cytocompatibility with human endothelial …
Multiple MitraClips: The balancing act between pressure gradient and regurgitation.
Gooden SC, Hatoum H, Zhang W, Boudoulas KD, Dasi LP. Gooden SC, et al. J Thorac Cardiovasc Surg. 2020 May 31:S0022-5223(20)31272-1. doi: 10.1016/j.jtcvs.2020.05.049. Online ahead of print. J Thorac Cardiovasc Surg. 2020. PMID: 32711989
The challenge is reducing MR while avoiding an elevated mitral valve gradient (MVG). This study assesses how multiple MitraClips used to treat MR can affect valve performance. METHODS: Six porcine mitral valves were assessed using an in vitro left heart simul …
The challenge is reducing MR while avoiding an elevated mitral valve gradient (MVG). This study assesses how multiple MitraClips used …
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