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Effects of a continuous remote care intervention including nutritional ketosis on kidney function and inflammation in adults with type 2 diabetes: a post-hoc latent class trajectory analysis.
Athinarayanan SJ, Roberts CGP, Phinney SD, Weimbs T, Friedman AN, Volek JS. Athinarayanan SJ, et al. Front Nutr. 2025 Jun 6;12:1609737. doi: 10.3389/fnut.2025.1609737. eCollection 2025. Front Nutr. 2025. PMID: 40547366 Free PMC article.
RESULTS: CCI participants experienced a significant eGFR slope increase of 0.91 mL/min/1.73m(2)/year, compared to a decline in UC (-0.68 mL/min/1.73m(2)/year). Greater mean BHB at 365 days (beta = 0.1, p = 0.002) was independently associated with greater eGFR improv …
RESULTS: CCI participants experienced a significant eGFR slope increase of 0.91 mL/min/1.73m(2)/year, compared to a decline in UC (-0 …
Post hoc analyses of surrogate markers of non-alcoholic fatty liver disease (NAFLD) and liver fibrosis in patients with type 2 diabetes in a digitally supported continuous care intervention: an open-label, non-randomised controlled study.
Vilar-Gomez E, Athinarayanan SJ, Adams RN, Hallberg SJ, Bhanpuri NH, McKenzie AL, Campbell WW, McCarter JP, Phinney SD, Volek JS, Chalasani N. Vilar-Gomez E, et al. BMJ Open. 2019 Feb 25;9(2):e023597. doi: 10.1136/bmjopen-2018-023597. BMJ Open. 2019. PMID: 30803948 Free PMC article.
At 1 year, weight loss of 5% was achieved in 79% of patients in the CCI versus 19% of patients in UC (p<0.001). ...NFS was reduced in the CCI group (-0.65 0.06, p<0.001) compared with UC (0.26 0.11, p=0.02) (p<0.001 between two groups). In the CCI group, t …
At 1 year, weight loss of 5% was achieved in 79% of patients in the CCI versus 19% of patients in UC (p<0.001). ...NFS was reduce …
Broad-Spectrum Effects of Carbohydrate Reduction on Inflammatory and Immune Mediators in Type 2 Diabetes.
Athinarayanan SJ, Phinney SD, Adams RN, Volek JS, Thurmond DC, McKenzie AL, Roberts CGP, Ratner RE, Krauss RM, Fonseca VA. Athinarayanan SJ, et al. Endocr Res. 2026 May;51(2):100-116. doi: 10.1080/07435800.2026.2659579. Epub 2026 Apr 17. Endocr Res. 2026. PMID: 41994946
METHODS: In this post-hoc analysis, adults with T2D (n = 195) or prediabetes (n = 89) in a two-year continuous care intervention (CCI) with individualized carbohydrate reduction emphasizing nutritional ketosis were compared with T2D participants receiving usual care …
METHODS: In this post-hoc analysis, adults with T2D (n = 195) or prediabetes (n = 89) in a two-year continuous care interventi …