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Ascorbate deficiency results in impaired neutrophil apoptosis and clearance and is associated with up-regulation of hypoxia-inducible factor 1α.
Vissers MCM, Wilkie RP. Vissers MCM, et al. J Leukoc Biol. 2007 May;81(5):1236-1244. doi: 10.1189/jlb.0806541. J Leukoc Biol. 2007. PMID: 29350811
The effect of intracellular ascorbate on the susceptibility of HL60 and Jurkat cells to chemotherapy agents.
Gokhalé P, Patel T, Morrison MJ, Vissers MC. Gokhalé P, et al. Apoptosis. 2006 Oct;11(10):1737-46. doi: 10.1007/s10495-006-9787-3. Apoptosis. 2006. PMID: 16951922
Ascorbate deficiency results in impaired neutrophil apoptosis and clearance and is associated with up-regulation of hypoxia-inducible factor 1alpha.
Vissers MC, Wilkie RP. Vissers MC, et al. J Leukoc Biol. 2007 May;81(5):1236-44. doi: 10.1189/jlb.0806541. Epub 2007 Jan 30. J Leukoc Biol. 2007. PMID: 17264304
A functional NADPH oxidase prevents caspase involvement in the clearance of phagocytic neutrophils.
Wilkie RP, Vissers MC, Dragunow M, Hampton MB. Wilkie RP, et al. Infect Immun. 2007 Jul;75(7):3256-63. doi: 10.1128/IAI.01984-06. Epub 2007 Apr 16. Infect Immun. 2007. PMID: 17438039 Free PMC article.
Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate.
Vissers MC, Gunningham SP, Morrison MJ, Dachs GU, Currie MJ. Vissers MC, et al. Free Radic Biol Med. 2007 Mar 15;42(6):765-72. doi: 10.1016/j.freeradbiomed.2006.11.023. Epub 2006 Nov 30. Free Radic Biol Med. 2007. PMID: 17320759
Nuclear factor kappaB activation in pulmonary leukocytes from infants with hyaline membrane disease: associations with chorioamnionitis and Ureaplasma urealyticum colonization.
Cheah FC, Winterbourn CC, Darlow BA, Mocatta TJ, Vissers MC. Cheah FC, et al. Pediatr Res. 2005 May;57(5 Pt 1):616-23. doi: 10.1203/01.PDR.0000156209.37627.82. Epub 2005 Mar 3. Pediatr Res. 2005. PMID: 15746262
Detection of apoptosis by caspase-3 activation in tracheal aspirate neutrophils from premature infants: relationship with NF-kappaB activation.
Cheah FC, Hampton MB, Darlow BA, Winterbourn CC, Vissers MC. Cheah FC, et al. J Leukoc Biol. 2005 Mar;77(3):432-7. doi: 10.1189/jlb.0904520. Epub 2004 Dec 16. J Leukoc Biol. 2005. PMID: 15604122
Extracellular oxidation by taurine chloramine activates ERK via the epidermal growth factor receptor.
Midwinter RG, Peskin AV, Vissers MC, Winterbourn CC. Midwinter RG, et al. J Biol Chem. 2004 Jul 30;279(31):32205-11. doi: 10.1074/jbc.M402070200. Epub 2004 May 27. J Biol Chem. 2004. PMID: 15166244
The effect of hypochlorous acid on the expression of adhesion molecules and activation of NF-kappaB in cultured human endothelial cells.
Pullar JM, Winterbourn CC, Vissers MC. Pullar JM, et al. Antioxid Redox Signal. 2002 Feb;4(1):5-15. doi: 10.1089/152308602753625807. Antioxid Redox Signal. 2002. PMID: 11970838
Oxidant-mediated phosphatidylserine exposure and macrophage uptake of activated neutrophils: possible impairment in chronic granulomatous disease.
Hampton MB, Vissers MC, Keenan JI, Winterbourn CC. Hampton MB, et al. J Leukoc Biol. 2002 May;71(5):775-81. J Leukoc Biol. 2002. PMID: 11994501
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