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Visualization of AMPA receptors in living human brain with positron emission tomography.
Miyazaki T, Nakajima W, Hatano M, Shibata Y, Kuroki Y, Arisawa T, Serizawa A, Sano A, Kogami S, Yamanoue T, Kimura K, Hirata Y, Takada Y, Ishiwata Y, Sonoda M, Tokunaga M, Seki C, Nagai Y, Minamimoto T, Kawamura K, Zhang MR, Ikegaya N, Iwasaki M, Kunii N, Kimura Y, Yamashita F, Taguri M, Tani H, Nagai N, Koizumi T, Nakajima S, Mimura M, Yuzaki M, Kato H, Higuchi M, Uchida H, Takahashi T. Miyazaki T, et al. Nat Med. 2020 Feb;26(2):281-288. doi: 10.1038/s41591-019-0723-9. Epub 2020 Jan 20. Nat Med. 2020. PMID: 31959988
Although aberrations in the number and function of glutamate AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors are thought to underlie neuropsychiatric disorders, no methods are currently available for visualizing AMPA recep
Although aberrations in the number and function of glutamate AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) rece
[(11)C]K-2 image with positron emission tomography represents cell surface AMPA receptors.
Arisawa T, Miyazaki T, Ota W, Sano A, Suyama K, Takada Y, Takahashi T. Arisawa T, et al. Neurosci Res. 2021 May 24:S0168-0102(21)00108-5. doi: 10.1016/j.neures.2021.05.009. Online ahead of print. Neurosci Res. 2021. PMID: 34033829 Free article.
The glutamate alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) is an important molecule in neurotransmission. We have recently developed the first positron emission tomography (PET) tracer [(11)C]K-2 to visualize and …
The glutamate alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) is an important molecule in neurotransmiss …