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486 results
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Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity.
Hoet RM, Cohen EH, Kent RB, Rookey K, Schoonbroodt S, Hogan S, Rem L, Frans N, Daukandt M, Pieters H, van Hegelsom R, Neer NC, Nastri HG, Rondon IJ, Leeds JA, Hufton SE, Huang L, Kashin I, Devlin M, Kuang G, Steukers M, Viswanathan M, Nixon AE, Sexton DJ, Hoogenboom HR, Ladner RC. Hoet RM, et al. Among authors: viswanathan m. Nat Biotechnol. 2005 Mar;23(3):344-8. doi: 10.1038/nbt1067. Epub 2005 Feb 20. Nat Biotechnol. 2005. PMID: 15723048
Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
Kenniston JA, Faucette RR, Martik D, Comeau SR, Lindberg AP, Kopacz KJ, Conley GP, Chen J, Viswanathan M, Kastrapeli N, Cosic J, Mason S, DiLeo M, Abendroth J, Kuzmic P, Ladner RC, Edwards TE, TenHoor C, Adelman BA, Nixon AE, Sexton DJ. Kenniston JA, et al. Among authors: viswanathan m. J Biol Chem. 2014 Aug 22;289(34):23596-608. doi: 10.1074/jbc.M114.569061. Epub 2014 Jun 26. J Biol Chem. 2014. PMID: 24970892 Free PMC article.
Screening isolates from antibody phage-display libraries.
Buckler DR, Park A, Viswanathan M, Hoet RM, Ladner RC. Buckler DR, et al. Among authors: viswanathan m. Drug Discov Today. 2008 Apr;13(7-8):318-24. doi: 10.1016/j.drudis.2007.10.012. Epub 2007 Nov 26. Drug Discov Today. 2008. PMID: 18405844 Review.
Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate.
Hills R, Mazzarella R, Fok K, Liu M, Nemirovskiy O, Leone J, Zack MD, Arner EC, Viswanathan M, Abujoub A, Muruganandam A, Sexton DJ, Bassill GJ, Sato AK, Malfait AM, Tortorella MD. Hills R, et al. Among authors: viswanathan m. J Biol Chem. 2007 Apr 13;282(15):11101-9. doi: 10.1074/jbc.M611588200. Epub 2007 Feb 20. J Biol Chem. 2007. PMID: 17311924
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