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Lin28: A microRNA regulator with a macro role.
Viswanathan SR, Daley GQ. Viswanathan SR, et al. Cell. 2010 Feb 19;140(4):445-9. doi: 10.1016/j.cell.2010.02.007. Cell. 2010. PMID: 20178735 Free article.
Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing.
Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, Zhang Z, Gydush GJ, Rotem D; PCF/SU2C International Prostate Cancer Dream Team, Love JC, Getz G, Gabriel S, Zhang CZ, Dehm SM, Nelson PS, Van Allen EM, Choudhury AD, Adalsteinsson VA, Beroukhim R, Taplin ME, Meyerson M. Viswanathan SR, et al. Cell. 2018 Jul 12;174(2):433-447.e19. doi: 10.1016/j.cell.2018.05.036. Epub 2018 Jun 18. Cell. 2018. PMID: 29909985 Free PMC article.
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies.
Zhu H, Shah S, Shyh-Chang N, Shinoda G, Einhorn WS, Viswanathan SR, Takeuchi A, Grasemann C, Rinn JL, Lopez MF, Hirschhorn JN, Palmert MR, Daley GQ. Zhu H, et al. Among authors: viswanathan sr. Nat Genet. 2010 Jul;42(7):626-30. doi: 10.1038/ng.593. Epub 2010 May 30. Nat Genet. 2010. PMID: 20512147 Free PMC article.
microRNA expression during trophectoderm specification.
Viswanathan SR, Mermel CH, Lu J, Lu CW, Golub TR, Daley GQ. Viswanathan SR, et al. PLoS One. 2009 Jul 3;4(7):e6143. doi: 10.1371/journal.pone.0006143. PLoS One. 2009. PMID: 19582159 Free PMC article.
A role for Lin28 in primordial germ-cell development and germ-cell malignancy.
West JA, Viswanathan SR, Yabuuchi A, Cunniff K, Takeuchi A, Park IH, Sero JE, Zhu H, Perez-Atayde A, Frazier AL, Surani MA, Daley GQ. West JA, et al. Among authors: viswanathan sr. Nature. 2009 Aug 13;460(7257):909-13. doi: 10.1038/nature08210. Epub 2009 Jul 5. Nature. 2009. PMID: 19578360 Free PMC article.
Lin28 promotes transformation and is associated with advanced human malignancies.
Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, Toffanin S, O'Sullivan M, Lu J, Phillips LA, Lockhart VL, Shah SP, Tanwar PS, Mermel CH, Beroukhim R, Azam M, Teixeira J, Meyerson M, Hughes TP, Llovet JM, Radich J, Mullighan CG, Golub TR, Sorensen PH, Daley GQ. Viswanathan SR, et al. Nat Genet. 2009 Jul;41(7):843-8. doi: 10.1038/ng.392. Epub 2009 May 31. Nat Genet. 2009. PMID: 19483683 Free PMC article.
Selective blockade of microRNA processing by Lin28.
Viswanathan SR, Daley GQ, Gregory RI. Viswanathan SR, et al. Science. 2008 Apr 4;320(5872):97-100. doi: 10.1126/science.1154040. Epub 2008 Feb 21. Science. 2008. PMID: 18292307 Free PMC article.
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.
Piskounova E, Viswanathan SR, Janas M, LaPierre RJ, Daley GQ, Sliz P, Gregory RI. Piskounova E, et al. Among authors: viswanathan sr. J Biol Chem. 2008 Aug 1;283(31):21310-4. doi: 10.1074/jbc.C800108200. Epub 2008 Jun 12. J Biol Chem. 2008. PMID: 18550544
LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans.
Tu HC, Schwitalla S, Qian Z, LaPier GS, Yermalovich A, Ku YC, Chen SC, Viswanathan SR, Zhu H, Nishihara R, Inamura K, Kim SA, Morikawa T, Mima K, Sukawa Y, Yang J, Meredith G, Fuchs CS, Ogino S, Daley GQ. Tu HC, et al. Among authors: viswanathan sr. Genes Dev. 2015 May 15;29(10):1074-86. doi: 10.1101/gad.256693.114. Epub 2015 May 8. Genes Dev. 2015. PMID: 25956904 Free PMC article.
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer.
Viswanathan SR, Nogueira MF, Buss CG, Krill-Burger JM, Wawer MJ, Malolepsza E, Berger AC, Choi PS, Shih J, Taylor AM, Tanenbaum B, Pedamallu CS, Cherniack AD, Tamayo P, Strathdee CA, Lage K, Carr SA, Schenone M, Bhatia SN, Vazquez F, Tsherniak A, Hahn WC, Meyerson M. Viswanathan SR, et al. Nat Genet. 2018 Jul;50(7):937-943. doi: 10.1038/s41588-018-0155-3. Epub 2018 Jun 28. Nat Genet. 2018. PMID: 29955178 Free PMC article.
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