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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 3
1976 2
1977 4
1979 4
1980 1
1981 5
1982 3
1983 2
1984 8
1985 5
1986 2
1987 8
1988 4
1989 3
1990 3
1991 3
1992 8
1993 15
1994 17
1995 25
1996 14
1997 15
1998 23
1999 35
2000 28
2001 38
2002 53
2003 54
2004 49
2005 59
2006 53
2007 41
2008 55
2009 51
2010 63
2011 84
2012 80
2013 89
2014 95
2015 95
2016 104
2017 99
2018 130
2019 140
2020 173
2021 205
2022 220
2023 221
2024 214
2025 281
2026 136

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2,809 results

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Page 1
The Roles of Vitamin C in Skin Health.
Pullar JM, Carr AC, Vissers MCM. Pullar JM, et al. Nutrients. 2017 Aug 12;9(8):866. doi: 10.3390/nu9080866. Nutrients. 2017. PMID: 28805671 Free PMC article. Review.
This knowledge is often used as a rationale for the addition of vitamin C to topical applications, but the efficacy of such treatment, as opposed to optimising dietary vitamin C intake, is poorly understood. This review discusses the potential roles fo …
This knowledge is often used as a rationale for the addition of vitamin C to topical applications, but the efficacy of such tr …
Vitamin C reduces the severity of common colds: a meta-analysis.
Hemilä H, Chalker E. Hemilä H, et al. BMC Public Health. 2023 Dec 11;23(1):2468. doi: 10.1186/s12889-023-17229-8. BMC Public Health. 2023. PMID: 38082300 Free PMC article. Review.
The direct comparison of the effect of vitamin C on mild and severe symptoms was limited to five comparisons which found that vitamin C had a significant benefit on the duration of severe symptoms. In this subset, there was a significant differe …
The direct comparison of the effect of vitamin C on mild and severe symptoms was limited to five comparisons which found that …
Two Faces of Vitamin C-Antioxidative and Pro-Oxidative Agent.
Kaźmierczak-Barańska J, Boguszewska K, Adamus-Grabicka A, Karwowski BT. Kaźmierczak-Barańska J, et al. Nutrients. 2020 May 21;12(5):1501. doi: 10.3390/nu12051501. Nutrients. 2020. PMID: 32455696 Free PMC article. Review.
Vitamin C has been known for decades. It is common in everyday use as an element of the diet, supplementation, and a preservative. ...Finally, we discuss the effect of vitamin C supplementation on biomarkers of oxidative DNA damage and review the evide …
Vitamin C has been known for decades. It is common in everyday use as an element of the diet, supplementation, and a preservat …
The role of vitamin C on the skin.
Makhakhe L. Makhakhe L. S Afr Fam Pract (2004). 2025 Jul 14;67(1):e1-e7. doi: 10.4102/safp.v67i1.6098. S Afr Fam Pract (2004). 2025. PMID: 40776734 Free PMC article. Review.
Vitamin C (ascorbic acid or ascorbate) plays an important role in regulating the health of the skin, promoting the differentiation of epithelial skin cells (keratinocytes) while contributing a notable role in the reduction of melanin synthesis, leading …
Vitamin C (ascorbic acid or ascorbate) plays an important role in regulating the health of the skin, promoting t …
Vitamin C as an antioxidant: evaluation of its role in disease prevention.
Padayatty SJ, Katz A, Wang Y, Eck P, Kwon O, Lee JH, Chen S, Corpe C, Dutta A, Dutta SK, Levine M. Padayatty SJ, et al. J Am Coll Nutr. 2003 Feb;22(1):18-35. doi: 10.1080/07315724.2003.10719272. J Am Coll Nutr. 2003. PMID: 12569111 Review.
Vitamin C in humans must be ingested for survival. Vitamin C is an electron donor, and this property accounts for all its known functions. ...Whether these protective effects are directly attributable to vitamin C is not known. Interventi …
Vitamin C in humans must be ingested for survival. Vitamin C is an electron donor, and this property accounts fo …
Vitamin C for the common cold and pneumonia.
Hemilä H, Chalker E. Hemilä H, et al. Pol Arch Intern Med. 2025 Jan 30;135(1):16926. doi: 10.20452/pamw.16926. Epub 2025 Jan 13. Pol Arch Intern Med. 2025. PMID: 39803741 Free article. Review.
This paper provides an overview of the efficacy of vitamin C for preventing and treating respiratory infections. Studies in a wide variety of animals have shown vitamin C to be protective against infections. ...Vitamin C has been tested f …
This paper provides an overview of the efficacy of vitamin C for preventing and treating respiratory infections. Studies in a …
Vitamin C pharmacokinetics: implications for oral and intravenous use.
Padayatty SJ, Sun H, Wang Y, Riordan HD, Hewitt SM, Katz A, Wesley RA, Levine M. Padayatty SJ, et al. Ann Intern Med. 2004 Apr 6;140(7):533-7. doi: 10.7326/0003-4819-140-7-200404060-00010. Ann Intern Med. 2004. PMID: 15068981 Free article.
BACKGROUND: Vitamin C at high concentrations is toxic to cancer cells in vitro. Early clinical studies of vitamin C in patients with terminal cancer suggested clinical benefit, but 2 double-blind, placebo-controlled trials showed none. ...Becaus …
BACKGROUND: Vitamin C at high concentrations is toxic to cancer cells in vitro. Early clinical studies of vitamin C …
Clinical benefits and risks of high-dose intravenous vitamin C: a systematic review.
Alangari A, Arif J, Al Qureshah F, Alkhodairy F. Alangari A, et al. J Med Life. 2026 Jan;19(1):16-23. doi: 10.25122/jml-2025-0176. J Med Life. 2026. PMID: 41815850 Free PMC article. Review.
High-dose intravenous vitamin C (IVC) achieves plasma concentrations that are not attainable by oral administration and has been investigated as an adjunct in sepsis, oncology, and symptom management. ...Pharmacokinetic and mechanistic studies of IVC support plausib …
High-dose intravenous vitamin C (IVC) achieves plasma concentrations that are not attainable by oral administration and has be …
The Role of Vitamin C in Selected Autoimmune and Immune-Mediated Diseases: Exploring Potential Therapeutic Benefits.
Mochol M, Jablonowski L, Pawlik A, Rasławska-Socha J, Chamarczuk A, Lipski M, Mazurek-Mochol M. Mochol M, et al. Int J Mol Sci. 2025 Sep 25;26(19):9375. doi: 10.3390/ijms26199375. Int J Mol Sci. 2025. PMID: 41096642 Free PMC article. Review.
Autoimmune diseases are characterized by immune response dysregulation against self-components, leading to chronic inflammation and tissue damage. Vitamin C (VitC), a water-soluble vitamin with established functions in antioxidant defence and collagen synthesis, has …
Autoimmune diseases are characterized by immune response dysregulation against self-components, leading to chronic inflammation and tissue d …
Vitamin C and Infections.
Hemilä H. Hemilä H. Nutrients. 2017 Mar 29;9(4):339. doi: 10.3390/nu9040339. Nutrients. 2017. PMID: 28353648 Free PMC article. Review.
Three controlled trials found that vitamin C prevented pneumonia. Two controlled trials found a treatment benefit of vitamin C for pneumonia patients. One controlled trial reported treatment benefits for tetanus patients. The effects of …
Three controlled trials found that vitamin C prevented pneumonia. Two controlled trials found a treatment benefit of …
2,809 results