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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1980 35
1981 43
1982 41
1983 45
1984 64
1985 80
1986 91
1987 82
1988 74
1989 84
1990 103
1991 123
1992 120
1993 137
1994 180
1995 192
1996 240
1997 224
1998 262
1999 263
2000 280
2001 278
2002 287
2003 320
2004 353
2005 345
2006 411
2007 395
2008 401
2009 451
2010 514
2011 544
2012 626
2013 649
2014 636
2015 665
2016 610
2017 668
2018 663
2019 602
2020 582
2021 180
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11,644 results
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Page 1
Where is the vitamin D receptor?
Wang Y, Zhu J, DeLuca HF. Wang Y, et al. Arch Biochem Biophys. 2012 Jul 1;523(1):123-33. doi: 10.1016/j.abb.2012.04.001. Epub 2012 Apr 6. Arch Biochem Biophys. 2012. PMID: 22503810 Review.
The vitamin D receptor (VDR) is a member of the nuclear receptor superfamily and plays a central role in the biological actions of vitamin D. VDR regulates the expression of numerous genes involved in calcium/phosphate homeostasis, cellul …
The vitamin D receptor (VDR) is a member of the nuclear receptor superfamily and plays a central role in the bio …
Vitamin D and Vitamin D Receptor: New Insights in the Treatment of Hypertension.
Lin L, Zhang L, Li C, Gai Z, Li Y. Lin L, et al. Curr Protein Pept Sci. 2019;20(10):984-995. doi: 10.2174/1389203720666190807130504. Curr Protein Pept Sci. 2019. PMID: 31389312 Review.
Since the vitamin D receptor (VDR) is widely distributed in vascular endothelial cells, vascular smooth muscle cells and cardiomyocytes, the role of vitamin D and VDR in hypertension has received extensive attention. ...Due to the high correlati …
Since the vitamin D receptor (VDR) is widely distributed in vascular endothelial cells, vascular smooth muscle cells an …
Vitamin D Receptor: A Novel Therapeutic Target for Kidney Diseases.
Yang S, Li A, Wang J, Liu J, Han Y, Zhang W, Li YC, Zhang H. Yang S, et al. Curr Med Chem. 2018;25(27):3256-3271. doi: 10.2174/0929867325666180214122352. Curr Med Chem. 2018. PMID: 29446731 Free PMC article. Review.
Mounting evidence from animal and clinical studies has suggested that Vitamin D Receptor (VDR) activation has beneficial effects on various renal diseases. ...
Mounting evidence from animal and clinical studies has suggested that Vitamin D Receptor (VDR) activation has beneficia …
Vitamin D receptor polymorphisms and diseases.
Valdivielso JM, Fernandez E. Valdivielso JM, et al. Clin Chim Acta. 2006 Sep;371(1-2):1-12. doi: 10.1016/j.cca.2006.02.016. Epub 2006 Mar 6. Clin Chim Acta. 2006. PMID: 16563362 Review.
The vitamin D endocrine system is central to the control of bone and calcium homeostasis. ...Expression and nuclear activation of the vitamin D receptor (VDR) are necessary for the effects of vitamin D. ...
The vitamin D endocrine system is central to the control of bone and calcium homeostasis. ...Expression and nuclear activation …
Vitamin D and human health: lessons from vitamin D receptor null mice.
Bouillon R, Carmeliet G, Verlinden L, van Etten E, Verstuyf A, Luderer HF, Lieben L, Mathieu C, Demay M. Bouillon R, et al. Endocr Rev. 2008 Oct;29(6):726-76. doi: 10.1210/er.2008-0004. Epub 2008 Aug 11. Endocr Rev. 2008. PMID: 18694980 Free PMC article. Review.
The precise mode of action and the full spectrum of activities of the vitamin D hormone, 1,25-dihydroxyvitamin D [1,25-(OH)(2)D], can now be better evaluated by critical analysis of mice with engineered deletion of the vitamin D recept
The precise mode of action and the full spectrum of activities of the vitamin D hormone, 1,25-dihydroxyvitamin D [1,25- …
Vitamin D receptor (VDR)-mediated actions of 1alpha,25(OH)2vitamin D3: genomic and non-genomic mechanisms.
Haussler MR, Jurutka PW, Mizwicki M, Norman AW. Haussler MR, et al. Best Pract Res Clin Endocrinol Metab. 2011 Aug;25(4):543-59. doi: 10.1016/j.beem.2011.05.010. Best Pract Res Clin Endocrinol Metab. 2011. PMID: 21872797 Review.
The conformationally flexible secosteroid, 1alpha,25(OH)2vitamin D3 (1alpha,25(OH)2D3) initiates biological responses via binding to the vitamin D receptor (VDR). The VDR contains two overlapping ligand binding sites, a genomic pocket (VDR-GP) and an alternat …
The conformationally flexible secosteroid, 1alpha,25(OH)2vitamin D3 (1alpha,25(OH)2D3) initiates biological responses via binding to the …
The function of vitamin D receptor in vitamin D action.
Kato S. Kato S. J Biochem. 2000 May;127(5):717-22. doi: 10.1093/oxfordjournals.jbchem.a022662. J Biochem. 2000. PMID: 10788778 Free article. Review.
Vitamin D has roles in a variety of biological actions such as calcium homeostasis, cell proliferation and cell differentiation to many target tissues. Most of these biological actions of vitamin D are now considered to be exerted through the nuclear
Vitamin D has roles in a variety of biological actions such as calcium homeostasis, cell proliferation and cell differentiatio
Identification of a novel melatonin-binding nuclear receptor: Vitamin D receptor.
Fang N, Hu C, Sun W, Xu Y, Gu Y, Wu L, Peng Q, Reiter RJ, Liu L. Fang N, et al. J Pineal Res. 2020 Jan;68(1):e12618. doi: 10.1111/jpi.12618. Epub 2019 Nov 11. J Pineal Res. 2020. PMID: 31631405
Previous studies confirmed that melatonin regulates Runx2 expression but the mechanism is unclear. There is a direct interaction between Runx2 and the vitamin D receptor (VDR). Herein, we observed a direct interaction between melatonin and the VDR but not Run …
Previous studies confirmed that melatonin regulates Runx2 expression but the mechanism is unclear. There is a direct interaction between Run …
Alternative binding sites at the vitamin D receptor and their ligands.
Mutchie TR, Yu OB, Di Milo ES, Arnold LA. Mutchie TR, et al. Mol Cell Endocrinol. 2019 Apr 5;485:1-8. doi: 10.1016/j.mce.2019.01.011. Epub 2019 Jan 14. Mol Cell Endocrinol. 2019. PMID: 30654005 Free PMC article. Review.
In recent decades, the majority of ligands developed for the vitamin D receptor (VDR) bind at its deeply buried genomic ligand binding pocket. ...Additional proposed interactions with VDR are discussed herein that include the alternative VDR-ligand binding po …
In recent decades, the majority of ligands developed for the vitamin D receptor (VDR) bind at its deeply buried genomic …
Vitamin D Receptor Activation in Liver Macrophages Protects Against Hepatic Endoplasmic Reticulum Stress in Mice.
Zhou Y, Dong B, Kim KH, Choi S, Sun Z, Wu N, Wu Y, Scott J, Moore DD. Zhou Y, et al. Hepatology. 2020 Apr;71(4):1453-1466. doi: 10.1002/hep.30887. Epub 2020 Jan 2. Hepatology. 2020. PMID: 31381163
However, it is not well defined how the interplay between ER stress and inflammation is regulated during hepatic stress response. APPROACH AND RESULTS: Here we demonstrate that vitamin D receptor (VDR) activation mitigates hepatic ER stress response, whereas …
However, it is not well defined how the interplay between ER stress and inflammation is regulated during hepatic stress response. APPROACH A …
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