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13,432 results

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Page 1
Vitamin D and Its Receptor from a Structural Perspective.
Rochel N. Rochel N. Nutrients. 2022 Jul 12;14(14):2847. doi: 10.3390/nu14142847. Nutrients. 2022. PMID: 35889804 Free PMC article. Review.
The activities of 1alpha,25-dihydroxyvitamin D3, 1,25D(3), are mediated via its binding to the vitamin D receptor (VDR), a ligand-dependent transcription factor that belongs to the nuclear receptor superfamily. ...
The activities of 1alpha,25-dihydroxyvitamin D3, 1,25D(3), are mediated via its binding to the vitamin D receptor (VDR) …
Methylation of the Vitamin D Receptor Gene in Human Disorders.
Gasperini B, Falvino A, Piccirilli E, Tarantino U, Botta A, Visconti VV. Gasperini B, et al. Int J Mol Sci. 2023 Dec 20;25(1):107. doi: 10.3390/ijms25010107. Int J Mol Sci. 2023. PMID: 38203278 Free PMC article. Review.
The Vitamin D Receptor (VDR) mediates the actions of 1,25-Dihydroxvitamin D3 (1,25(OH)(2)D(3)), which has important roles in bone homeostasis, growth/differentiation of cells, immune functions, and reduction of inflammation. ...
The Vitamin D Receptor (VDR) mediates the actions of 1,25-Dihydroxvitamin D3 (1,25(OH)(2)D(3)), which has important rol …
Vitamin D receptor gene polymorphisms and osteoarthritis: a meta-analysis.
Li HM, Liu Y, Zhang RJ, Ding JY, Shen CL. Li HM, et al. Rheumatology (Oxford). 2021 Feb 1;60(2):538-548. doi: 10.1093/rheumatology/keaa644. Rheumatology (Oxford). 2021. PMID: 33147632 Review.
OBJECTIVE: To investigate the association of vitamin D receptor (VDR) gene polymorphisms with OA susceptibility. METHODS: Meta-analyses were performed using allelic contrast, contrast of homozygotes, and recessive and dominant models to clarify the associatio …
OBJECTIVE: To investigate the association of vitamin D receptor (VDR) gene polymorphisms with OA susceptibility. METHOD …
Vitamin D and Its Target Genes.
Carlberg C. Carlberg C. Nutrients. 2022 Mar 24;14(7):1354. doi: 10.3390/nu14071354. Nutrients. 2022. PMID: 35405966 Free PMC article. Review.
The vitamin D metabolite 1alpha,25-dihydroxyvitamin D(3) is the natural, high-affinity ligand of the transcription factor vitamin D receptor (VDR). In many tissues and cell types, VDR binds in a ligand-dependent fashion to thousands of genomic loci and modula …
The vitamin D metabolite 1alpha,25-dihydroxyvitamin D(3) is the natural, high-affinity ligand of the transcription factor vitamin
Vitamin D-Mediated Regulation of Intestinal Calcium Absorption.
Fleet JC. Fleet JC. Nutrients. 2022 Aug 16;14(16):3351. doi: 10.3390/nu14163351. Nutrients. 2022. PMID: 36014856 Free PMC article. Review.
Intestinal Ca absorption is regulated by 1,25 dihydroxyvitamin D (1,25(OH)(2) D), a hormone that activates gene transcription following binding to the intestinal vitamin D receptor (VDR). When dietary Ca intake is low, Ca absorption follows a vitamin-D-regula …
Intestinal Ca absorption is regulated by 1,25 dihydroxyvitamin D (1,25(OH)(2) D), a hormone that activates gene transcription following bind …
Vitamin D Receptor: A Novel Therapeutic Target for Kidney Diseases.
Yang S, Li A, Wang J, Liu J, Han Y, Zhang W, Li YC, Zhang H. Yang S, et al. Curr Med Chem. 2018;25(27):3256-3271. doi: 10.2174/0929867325666180214122352. Curr Med Chem. 2018. PMID: 29446731 Free PMC article. Review.
Mounting evidence from animal and clinical studies has suggested that Vitamin D Receptor (VDR) activation has beneficial effects on various renal diseases. METHODS: A structured search of published research literature regarding VDR structure and function, VDR …
Mounting evidence from animal and clinical studies has suggested that Vitamin D Receptor (VDR) activation has beneficia …
Vitamin D and Vitamin D Receptor: New Insights in the Treatment of Hypertension.
Lin L, Zhang L, Li C, Gai Z, Li Y. Lin L, et al. Curr Protein Pept Sci. 2019;20(10):984-995. doi: 10.2174/1389203720666190807130504. Curr Protein Pept Sci. 2019. PMID: 31389312 Review.
But abundant research has shown that vitamin D also plays a regulatory role in autoimmunity, inflammation, angiogenesis and vascular cell activity. Since the vitamin D receptor (VDR) is widely distributed in vascular endothelial cells, vascular smooth muscle …
But abundant research has shown that vitamin D also plays a regulatory role in autoimmunity, inflammation, angiogenesis and vascular cell ac …
Modulation of the vitamin D/vitamin D receptor system in osteoporosis pathogenesis: insights and therapeutic approaches.
Li Y, Zhao P, Jiang B, Liu K, Zhang L, Wang H, Tian Y, Li K, Liu G. Li Y, et al. J Orthop Surg Res. 2023 Nov 13;18(1):860. doi: 10.1186/s13018-023-04320-4. J Orthop Surg Res. 2023. PMID: 37957749 Free PMC article. Review.
The biological effects of VD are primarily mediated through the vitamin D receptor (VDR), a nuclear receptor that regulates the transcription of target genes involved in calcium and phosphate metabolism, bone mineralization, and bone remodeling. In this revie …
The biological effects of VD are primarily mediated through the vitamin D receptor (VDR), a nuclear receptor that regul …
Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view.
Carlberg C, Molnár F. Carlberg C, et al. Can J Physiol Pharmacol. 2015 May;93(5):311-8. doi: 10.1139/cjpp-2014-0383. Epub 2015 Jan 21. Can J Physiol Pharmacol. 2015. PMID: 25741777 Review.
Vitamin D3 is one of the few natural compounds that has, via its metabolite 1alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3) and the transcription factor vitamin D receptor (VDR), a direct effect on gene regulation. For efficiently applying the therapeutic and dis …
Vitamin D3 is one of the few natural compounds that has, via its metabolite 1alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3) and the transcriptio …
Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate.
Oda Y, Wong CT, Oh DH, Meyer MB, Pike JW, Bikle DD. Oda Y, et al. J Steroid Biochem Mol Biol. 2023 Sep;232:106352. doi: 10.1016/j.jsbmb.2023.106352. Epub 2023 Jun 16. J Steroid Biochem Mol Biol. 2023. PMID: 37330071 Free PMC article.
The vitamin D receptor with its ligand 1,25 dihydroxy vitamin D(3) (1,25D(3)) regulates epidermal stem cell fate, such that VDR removal from Krt14 expressing keratinocytes delays re-epithelialization of epidermis after wound injury in mice. ...
The vitamin D receptor with its ligand 1,25 dihydroxy vitamin D(3) (1,25D(3)) regulates epidermal stem cell fate, such …
13,432 results
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