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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1921 1
1924 1
1940 2
1942 1
1946 1
1947 1
1959 2
1960 1
1962 1
1963 1
1970 1
1972 1
1980 1
1982 1
1983 1
1984 1
1985 1
1986 1
1987 1
1989 2
1990 1
1991 3
1992 3
1993 2
1994 4
1995 2
1996 7
1997 9
1998 10
1999 9
2000 15
2001 16
2002 10
2003 17
2004 12
2005 26
2006 23
2007 28
2008 35
2009 45
2010 41
2011 41
2012 47
2013 65
2014 53
2015 41
2016 50
2017 55
2018 54
2019 61
2020 48
2021 8
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778 results
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Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review.
Cerqueira RO, Frey BN, Leclerc E, Brietzke E. Cerqueira RO, et al. Arch Womens Ment Health. 2017 Dec;20(6):713-719. doi: 10.1007/s00737-017-0791-0. Epub 2017 Oct 23. Arch Womens Ment Health. 2017. PMID: 29063202 Review.
The objective of this study was to evaluate whether Vitex agnus castus is a safe and effective treatment for PMS and premenstrual dysphoric disorder (PMDD) and to discuss the implications of these findings for clinical practice. ...The inclusion criteria were …
The objective of this study was to evaluate whether Vitex agnus castus is a safe and effective treatment for PMS and pr …
Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials.
van Die MD, Burger HG, Teede HJ, Bone KM. van Die MD, et al. Planta Med. 2013 May;79(7):562-75. doi: 10.1055/s-0032-1327831. Epub 2012 Nov 7. Planta Med. 2013. PMID: 23136064 Free article. Review.
Vitex agnus-castus L. (chaste tree; chasteberry) is a popular herbal treatment, predominantly used for a range of female reproductive conditions in Anglo-American and European practice. ...In premenstrual dysphoric disorder, one study reported Vitex to
Vitex agnus-castus L. (chaste tree; chasteberry) is a popular herbal treatment, predominantly used for a range of femal
Systematic Review of Premenstrual, Postmenstrual and Infertility Disorders of Vitex Agnus Castus.
Rafieian-Kopaei M, Movahedi M. Rafieian-Kopaei M, et al. Electron Physician. 2017 Jan 25;9(1):3685-3689. doi: 10.19082/3685. eCollection 2017 Jan. Electron Physician. 2017. PMID: 28243425 Free PMC article. Review.
INTRODUCTION: Vitex agnus-castus, also called vitex is aboriginal to the Mediterranean region, with long leaves, tender stem, flowers and ripening seeds. ...RESULT: Vitex agnus-castus was shown to contribute to the treatment of pre …
INTRODUCTION: Vitex agnus-castus, also called vitex is aboriginal to the Mediterranean region, with long leaves, …
Vitex agnus castus: a systematic review of adverse events.
Daniele C, Thompson Coon J, Pittler MH, Ernst E. Daniele C, et al. Drug Saf. 2005;28(4):319-32. doi: 10.2165/00002018-200528040-00004. Drug Saf. 2005. PMID: 15783241 Review.
Vitex agnus castus L. (VAC) [Verbenaceae] is a deciduous shrub that is native to Mediterranean Europe and Central Asia. ...
Vitex agnus castus L. (VAC) [Verbenaceae] is a deciduous shrub that is native to Mediterranean Europe and Central Asia.
Vitex agnus-castus in premenstrual syndrome: A meta-analysis of double-blind randomised controlled trials.
Csupor D, Lantos T, Hegyi P, Benkő R, Viola R, Gyöngyi Z, Csécsei P, Tóth B, Vasas A, Márta K, Rostás I, Szentesi A, Matuz M. Csupor D, et al. Complement Ther Med. 2019 Dec;47:102190. doi: 10.1016/j.ctim.2019.08.024. Epub 2019 Aug 30. Complement Ther Med. 2019. PMID: 31780016 Review.
Although chasteberry (Vitex agnus-castus, VAC) has been studied in several clinical trials and available as medicine for the alleviation of premenstrual syndrome (PMS) symptoms, the efficacy of properly characterised preparations has not been assessed in meta …
Although chasteberry (Vitex agnus-castus, VAC) has been studied in several clinical trials and available as medicine fo …
Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications.
Wuttke W, Jarry H, Christoffel V, Spengler B, Seidlová-Wuttke D. Wuttke W, et al. Phytomedicine. 2003 May;10(4):348-57. doi: 10.1078/094471103322004866. Phytomedicine. 2003. PMID: 12809367 Review.
Extracts of the fruits of chaste tree (Vitex agnus castus = AC) are widely used to treat premenstrual symptoms. ...Hence, it is concluded that dopaminergic compounds present in Vitex agnus castus are clinically the important compounds whi …
Extracts of the fruits of chaste tree (Vitex agnus castus = AC) are widely used to treat premenstrual symptoms. ...Henc …
The treatment of premenstrual syndrome with preparations of Vitex agnus castus: a systematic review and meta-analysis.
Verkaik S, Kamperman AM, van Westrhenen R, Schulte PFJ. Verkaik S, et al. Am J Obstet Gynecol. 2017 Aug;217(2):150-166. doi: 10.1016/j.ajog.2017.02.028. Epub 2017 Feb 22. Am J Obstet Gynecol. 2017. PMID: 28237870 Review.
Apart from conventional drugs, like serotonin reuptake inhibitors and oral contraceptives, complementary and alternative medicines such as Vitex agnus castus are used by many women experiencing PMS. OBJECTIVE: Our objective was to determine the efficacy, tole …
Apart from conventional drugs, like serotonin reuptake inhibitors and oral contraceptives, complementary and alternative medicines such as …
The effects of Vitex agnus-castus on menstrual bleeding: A systematic review and meta-analysis.
Mollazadeh S, Mirghafourvand M, Abdollahi NG. Mollazadeh S, et al. J Complement Integr Med. 2019 Jul 31;17(1):/j/jcim.2019.17.issue-1/jcim-2018-0053/jcim-2018-0053.xml. doi: 10.1515/jcim-2018-0053. J Complement Integr Med. 2019. PMID: 31369395
Introduction Vitex agnus-castus, also called Vitex, is a plant with many medicinal properties. ...Only nausea and abdominal pain were reported as side effects of Vitex in the included studies. Conclusions The results of this study showed that th …
Introduction Vitex agnus-castus, also called Vitex, is a plant with many medicinal properties. ...Only nausea an …
Vitex Agnus-Castus for the Treatment of Cyclic Mastalgia: A Systematic Review and Meta-Analysis.
Ooi SL, Watts S, McClean R, Pak SC. Ooi SL, et al. J Womens Health (Larchmt). 2020 Feb;29(2):262-278. doi: 10.1089/jwh.2019.7770. Epub 2019 Aug 29. J Womens Health (Larchmt). 2020. PMID: 31464546
It may associate with latent hyperprolactinemia due to the insufficient inhibitory effect of dopamine on the pituitary gland. Vitex agnus-castus (VAC) is known for its dopaminergic activity and its possible actions on CM and latent hyperprolactinemia. ...
It may associate with latent hyperprolactinemia due to the insufficient inhibitory effect of dopamine on the pituitary gland. Vitex
Therapeutic effect of Vitex agnus castus in patients with premenstrual syndrome.
Zamani M, Neghab N, Torabian S. Zamani M, et al. Acta Med Iran. 2012;50(2):101-6. Acta Med Iran. 2012. PMID: 22359078 Free article. Clinical Trial.
Herbal remedies rarely have side effects and people have more tendencies toward them than chemical therapies. In this study the therapeutic effect of Vitex agnus castus on women who had the PMS, in comparison with placebo, were investigated. ...The mean age w …
Herbal remedies rarely have side effects and people have more tendencies toward them than chemical therapies. In this study the therapeutic …
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