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Centrosomes, chromosome instability (CIN) and aneuploidy.
Vitre BD, Cleveland DW. Vitre BD, et al. Curr Opin Cell Biol. 2012 Dec;24(6):809-15. doi: 10.1016/j.ceb.2012.10.006. Epub 2012 Nov 3. Curr Opin Cell Biol. 2012. PMID: 23127609 Free PMC article. Review.
Chronic centrosome amplification without tumorigenesis.
Vitre B, Holland AJ, Kulukian A, Shoshani O, Hirai M, Wang Y, Maldonado M, Cho T, Boubaker J, Swing DA, Tessarollo L, Evans SM, Fuchs E, Cleveland DW. Vitre B, et al. Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6321-30. doi: 10.1073/pnas.1519388112. Epub 2015 Nov 2. Proc Natl Acad Sci U S A. 2015. PMID: 26578792 Free PMC article.
Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals.
Levine MS, Bakker B, Boeckx B, Moyett J, Lu J, Vitre B, Spierings DC, Lansdorp PM, Cleveland DW, Lambrechts D, Foijer F, Holland AJ. Levine MS, et al. Among authors: vitre b. Dev Cell. 2017 Feb 6;40(3):313-322.e5. doi: 10.1016/j.devcel.2016.12.022. Epub 2017 Jan 26. Dev Cell. 2017. PMID: 28132847 Free PMC article.
Transient genomic instability drives tumorigenesis through accelerated clonal evolution.
Shoshani O, Bakker B, de Haan L, Tijhuis AE, Wang Y, Kim DH, Maldonado M, Demarest MA, Artates J, Zhengyu O, Mark A, Wardenaar R, Sasik R, Spierings DCJ, Vitre B, Fisch K, Foijer F, Cleveland DW. Shoshani O, et al. Among authors: vitre b. Genes Dev. 2021 Aug 1;35(15-16):1093-1108. doi: 10.1101/gad.348319.121. Epub 2021 Jul 15. Genes Dev. 2021. PMID: 34266887 Free PMC article.
19 results