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Hemopexin deficiency promotes acute kidney injury in sickle cell disease.

Ofori-Acquah SF, Hazra R, Orikogbo OO, Crosby D, Flage B, Ackah EB, Lenhart D, Tan RJ, Vitturi DA, Paintsil V, Owusu-Dabo E, Ghosh S; SickleGenAfrica Network. Ofori-Acquah SF, et al. Among authors: vitturi da. Blood. 2020 Mar 26;135(13):1044-1048. doi: 10.1182/blood.2019002653. Blood. 2020. PMID: 32043112

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Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus.

Jobbagy S, Vitturi DA, Salvatore SR, Pires MF, Rowart P, Emlet DR, Ross M, Hahn S, St Croix C, Wendell SG, Subramanya AR, Straub AC, Tan RJ, Schopfer FJ. Jobbagy S, et al. Among authors: vitturi da. JCI Insight. 2020 Jan 16;5(1):e128578. doi: 10.1172/jci.insight.128578. JCI Insight. 2020. PMID: 31941842 Free PMC article.

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Nitro-fatty acids as activators of hSIRT6 deacetylase activity.

Carreño M, Bresque M, Machado MR, Santos L, Durán R, Vitturi DA, Escande C, Denicola A. Carreño M, et al. Among authors: vitturi da. J Biol Chem. 2020 Dec 25;295(52):18355-18366. doi: 10.1074/jbc.RA120.014883. Epub 2020 Oct 29. J Biol Chem. 2020. PMID: 33122195

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Xanthine Oxidase Drives Hemolysis and Vascular Malfunction in Sickle Cell Disease.

Schmidt HM, Wood KC, Lewis SE, Hahn SA, Williams XM, McMahon B, Baust JJ, Yuan S, Bachman TN, Wang Y, Oh JY, Ghosh S, Ofori-Acquah SF, Lebensburger JD, Patel RP, Du J, Vitturi DA, Kelley EE, Straub AC. Schmidt HM, et al. Among authors: vitturi da. Arterioscler Thromb Vasc Biol. 2020 Dec 3:ATVBAHA120315081. doi: 10.1161/ATVBAHA.120.315081. Online ahead of print. Arterioscler Thromb Vasc Biol. 2020. PMID: 33267657

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Nitro-fatty acids: New drug candidates for chronic inflammatory and fibrotic diseases.

Schopfer FJ, Vitturi DA, Jorkasky DK, Freeman BA. Schopfer FJ, et al. Among authors: vitturi da. Nitric Oxide. 2018 Sep 1;79:31-37. doi: 10.1016/j.niox.2018.06.006. Epub 2018 Jun 23. Nitric Oxide. 2018. PMID: 29944935 Free PMC article. Review.

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Nitrite elicits divergent NO-dependent signaling that associates with outcome in out of hospital cardiac arrest.

Vitturi DA, Maynard C, Olsufka M, Straub AC, Krehel N, Kudenchuk PJ, Nichol G, Sayre M, Kim F, Dezfulian C. Vitturi DA, et al. Redox Biol. 2020 May;32:101463. doi: 10.1016/j.redox.2020.101463. Epub 2020 Feb 14. Redox Biol. 2020. PMID: 32087553 Free PMC article.

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Smooth muscle cytochrome b5 reductase 3 deficiency accelerates pulmonary hypertension development in sickle cell mice.

Wood KC, Durgin BG, Schmidt HM, Hahn SA, Baust JJ, Bachman T, Vitturi DA, Ghosh S, Ofori-Acquah SF, Mora AL, Gladwin MT, Straub AC. Wood KC, et al. Among authors: vitturi da. Blood Adv. 2019 Dec 10;3(23):4104-4116. doi: 10.1182/bloodadvances.2019000621. Blood Adv. 2019. PMID: 31821458 Free PMC article.

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Hemoglobin alters vitamin carrier uptake and vitamin D metabolism in proximal tubule cells: implications for sickle cell disease.

Gliozzi ML, Rbaibi Y, Long KR, Vitturi DA, Weisz OA. Gliozzi ML, et al. Among authors: vitturi da. Am J Physiol Cell Physiol. 2019 Nov 1;317(5):C993-C1000. doi: 10.1152/ajpcell.00287.2019. Epub 2019 Sep 11. Am J Physiol Cell Physiol. 2019. PMID: 31509446 Free PMC article.

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Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis.

Jobbagy S, Vitturi DA, Salvatore SR, Turell L, Pires MF, Kansanen E, Batthyany C, Lancaster JR Jr, Freeman BA, Schopfer FJ. Jobbagy S, et al. Among authors: vitturi da. Redox Biol. 2019 Feb;21:101050. doi: 10.1016/j.redox.2018.11.008. Epub 2018 Nov 22. Redox Biol. 2019. PMID: 30654300 Free PMC article.

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Evaluation of 10-Nitro Oleic Acid Bio-Elimination in Rats and Humans.

Salvatore SR, Vitturi DA, Fazzari M, Jorkasky DK, Schopfer FJ. Salvatore SR, et al. Among authors: vitturi da. Sci Rep. 2017 Jan 5;7:39900. doi: 10.1038/srep39900. Sci Rep. 2017. PMID: 28054588 Free PMC article.

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