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The activity of a novel mithramycin analog is related to its binding to DNA, cellular accumulation, and inhibition of Sp1-driven gene transcription.
Fernández-Guizán A, Mansilla S, Barceló F, Vizcaíno C, Núñez LE, Morís F, González S, Portugal J. Fernández-Guizán A, et al. Among authors: vizcaino c. Chem Biol Interact. 2014 Aug 5;219:123-32. doi: 10.1016/j.cbi.2014.05.019. Epub 2014 Jun 4. Chem Biol Interact. 2014. PMID: 24907531 Free article.
In vitro and in vivo studies for assessing the immune response and protection-inducing ability conferred by Fasciola hepatica-derived synthetic peptides containing B- and T-cell epitopes.
Rojas-Caraballo J, López-Abán J, Pérez del Villar L, Vizcaíno C, Vicente B, Fernández-Soto P, del Olmo E, Patarroyo MA, Muro A. Rojas-Caraballo J, et al. Among authors: vizcaino c. PLoS One. 2014 Aug 14;9(8):e105323. doi: 10.1371/journal.pone.0105323. eCollection 2014. PLoS One. 2014. PMID: 25122166 Free PMC article.
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