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CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells.
Vlassis A, Jensen TL, Mohr M, Jedrzejczyk DJ, Meng X, Kovacs G, Morera-Gómez M, Barghetti A, Muyo Abad S, Baumgartner RF, Natarajan KN, Nielsen LK, Warnecke T, Gill RT. Vlassis A, et al. iScience. 2023 Oct 27;26(12):108287. doi: 10.1016/j.isci.2023.108287. eCollection 2023 Dec 15. iScience. 2023. PMID: 38034357 Free PMC article.
The CRISPR-Cas12a Platform for Accurate Genome Editing, Gene Disruption, and Efficient Transgene Integration in Human Immune Cells.
Mohr M, Damas N, Gudmand-Høyer J, Zeeberg K, Jedrzejczyk D, Vlassis A, Morera-Gómez M, Pereira-Schoning S, Puš U, Oliver-Almirall A, Lyholm Jensen T, Baumgartner R, Tate Weinert B, Gill RT, Warnecke T. Mohr M, et al. Among authors: vlassis a. ACS Synth Biol. 2023 Feb 17;12(2):375-389. doi: 10.1021/acssynbio.2c00179. Epub 2023 Feb 7. ACS Synth Biol. 2023. PMID: 36750230 Free PMC article.
BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation.
Feng Y, Vlassis A, Roques C, Lalonde ME, González-Aguilera C, Lambert JP, Lee SB, Zhao X, Alabert C, Johansen JV, Paquet E, Yang XJ, Gingras AC, Côté J, Groth A. Feng Y, et al. Among authors: vlassis a. EMBO J. 2016 Jan 18;35(2):176-92. doi: 10.15252/embj.201591293. Epub 2015 Nov 30. EMBO J. 2016. PMID: 26620551 Free PMC article.