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Protein UFMylation regulates early events during ribosomal DNA-damage response.
Panichnantakul P, Aguilar LC, Daynard E, Guest M, Peters C, Vogel J, Oeffinger M. Panichnantakul P, et al. Among authors: vogel j. Cell Rep. 2024 Sep 24;43(9):114738. doi: 10.1016/j.celrep.2024.114738. Epub 2024 Sep 14. Cell Rep. 2024. PMID: 39277864 Free article.
Here, we identify protein UFMylation as essential for rDNA-damage response in human cells. We further show the only ubiquitin-fold modifier 1 (UFM1)-E3 ligase UFL1 and its binding partner DDRGK1 localize to nucleolar caps upon rDNA damage and that UFL1 loss impairs ATM act …
Here, we identify protein UFMylation as essential for rDNA-damage response in human cells. We further show the only ubiquitin-fold mo …
Control at the cell center: the role of spindle poles in cytoskeletal organization and cell cycle regulation.
Cuschieri L, Nguyen T, Vogel J. Cuschieri L, et al. Among authors: vogel j. Cell Cycle. 2007 Nov 15;6(22):2788-94. doi: 10.4161/cc.6.22.4941. Epub 2007 Aug 27. Cell Cycle. 2007. PMID: 17986861 Review.
However, recent studies propose that the function of MTOC components extends far beyond these established roles. Numerous cell cycle regulators, checkpoint proteins and microtubule plus tip binding proteins localize to MTOCs during the cell cycle, suggesting that th …
However, recent studies propose that the function of MTOC components extends far beyond these established roles. Numerous cell cycle …
Analysis of microtubules in budding yeast.
Rauch A, Nazarova E, Vogel J. Rauch A, et al. Among authors: vogel j. Methods Cell Biol. 2010;97:277-306. doi: 10.1016/S0091-679X(10)97016-7. Methods Cell Biol. 2010. PMID: 20719277 Review. No abstract available.
Kar9 symmetry breaking alone is insufficient to ensure spindle alignment.
Meziane M, Genthial R, Vogel J. Meziane M, et al. Among authors: vogel j. Sci Rep. 2021 Feb 19;11(1):4227. doi: 10.1038/s41598-021-83136-w. Sci Rep. 2021. PMID: 33608583 Free PMC article.
Spindle positioning must be tightly regulated to ensure asymmetric cell divisions are successful. In budding yeast, spindle positioning is mediated by the asymmetric localization of microtubule + end tracking protein Kar9. ...We report the spindles are not aligned in the m …
Spindle positioning must be tightly regulated to ensure asymmetric cell divisions are successful. In budding yeast, spindle positioni …
Dissection of Cdk1-cyclin complexes in vivo.
Ear PH, Booth MJ, Abd-Rabbo D, Kowarzyk Moreno J, Hall C, Chen D, Vogel J, Michnick SW. Ear PH, et al. Among authors: vogel j. Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15716-21. doi: 10.1073/pnas.1305420110. Epub 2013 Sep 9. Proc Natl Acad Sci U S A. 2013. PMID: 24019491 Free PMC article.
Cyclin-dependent kinases (Cdks) are regulatory enzymes with temporal and spatial selectivity for their protein substrates that are governed by cell cycle-regulated cyclin subunits. Specific cyclin-Cdk complexes bind to and phosphorylate target proteins, coupling their acti …
Cyclin-dependent kinases (Cdks) are regulatory enzymes with temporal and spatial selectivity for their protein substrates that are governed …
SAD kinase keeps centrosomes lonely.
Chen D, Vogel J. Chen D, et al. Among authors: vogel j. Nat Cell Biol. 2009 Sep;11(9):1047-8. doi: 10.1038/ncb0909-1047. Nat Cell Biol. 2009. PMID: 19724257
Centrosome duplication is under strict control such that it occurs only once per cell cycle. New insights into the molecular mechanisms that control centrosome number come from the discovery of a role for SADB kinase in centrosome biogenesis....
Centrosome duplication is under strict control such that it occurs only once per cell cycle. New insights into the molecular mechanis …
Inferring time derivatives including cell growth rates using Gaussian processes.
Swain PS, Stevenson K, Leary A, Montano-Gutierrez LF, Clark IB, Vogel J, Pilizota T. Swain PS, et al. Among authors: vogel j. Nat Commun. 2016 Dec 12;7:13766. doi: 10.1038/ncomms13766. Nat Commun. 2016. PMID: 27941811 Free PMC article.
Often the time derivative of a measured variable is of as much interest as the variable itself. For a growing population of biological cells, for example, the population's growth rate is typically more important than its size. ...As illustrations, we infer growth rates of …
Often the time derivative of a measured variable is of as much interest as the variable itself. For a growing population of biological ce
A cell cycle phosphoproteome of the yeast centrosome.
Keck JM, Jones MH, Wong CC, Binkley J, Chen D, Jaspersen SL, Holinger EP, Xu T, Niepel M, Rout MP, Vogel J, Sidow A, Yates JR 3rd, Winey M. Keck JM, et al. Among authors: vogel j. Science. 2011 Jun 24;332(6037):1557-61. doi: 10.1126/science.1205193. Science. 2011. PMID: 21700874 Free PMC article.
Mass spectrometry was used to identify 297 phosphorylation sites on centrosomes from different cell cycle stages. We observed different modes of phosphoregulation via specific protein kinases, phosphorylation site clustering, and conserved phosphorylated residues. ...
Mass spectrometry was used to identify 297 phosphorylation sites on centrosomes from different cell cycle stages. We observed differe …
29 results